Abstract: Methods and systems are described for providing deep brain stimulation (DBS) of the subcallosal cingulate region (SCC) to provide symptom relief in patients with treatment-resistant depression (TRD). The DBS devices may enable chronic electrophysiology recording to deliver SCC DBS therapy. One or more machine-learning models may identify SCC LFP changes that indicate the patient's current clinical state. The clinical state is distinct from acute transient stimulation effects, is sensitive to DBS stimulation adjustments, and accurately captures individual differences in recovery trajectory.

Abstract: In a computer system containing an object server, a method and apparatus for providing access to objects and methods via arbitrary remote protocols is disclosed. This includes a mechanism known as the protocol adapter framework that allows protocol adapters to manage remote socket sessions, encrypt communication on this session, translate text to the local character set, perform security validation of the remote user, log incoming work requests, classify the incoming work request for differentiated service purposes, and queue the work for execution. Also, included is a mechanism to invoke the protocol adapter in order to manipulate output from the execution of a method on a server object and send it back to the original requester. This allows the implementers of objects and methods that reside in the object server rather than the owner of the object server to provide a protocol adapter that allows communication with remote clients using any arbitrary protocol that the object implementer deems appropriate.

Abstract: In a heterogeneuos work environment a method and apparatus for managing isochronous streaming servers is disclosed. This includes a mechanism for allocating processor resource to streaming servers at admission control time with respect to the business importance of work they will be running. This mechanism includes a provision to preempt currently running streaming work of lesser business importance in order to allocate its share of the processor to the new higher importance work. Also included is a mechanism to resume the server when a running stream terminated and processor becomes available. In the case of the variable bit rate multiple peak problem a mechanism is presented to preempt running streaming work at the lowest business importance so that higher priority work can continue to run unaffected. The mechanism to resume paused streams at the termination of a stream also restarts this work.

Abstract: In a computer system containing an object server, a method and apparatus for providing access to objects and methods via arbitrary remote protocols is disclosed. This includes a mechanism known as the protocol adapter framework that allows protocol adapters to manage remote socket sessions, encrypt communication on this session, translate text to the local character set, perform security validation of the remote user, log incoming work requests, classify the incoming work request for differentiated service purposes, and queue the work for execution. Also, included is a mechanism to invoke the protocol adapter in order to manipulate output from the execution of a method on a server object and send it back to the original requester. This allows the implementers of objects and methods that reside in the object server rather than the owner of the object server to provide a protocol adapter that allows communication with remote clients using any arbitrary protocol that the object implementer deems appropriate.