Patents by Inventor Stephen Hendricks

Stephen Hendricks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11760997
    Abstract: Compositions, systems, and methods for the display of analytes such as biomolecules are described. Display of analytes is achieved by coupling of the analytes to displaying molecules that are configured to associate with surfaces or interfaces. Arrays of analytes may be formed from the described systems for utilization in assays and other methods.
    Type: Grant
    Filed: October 28, 2022
    Date of Patent: September 19, 2023
    Assignee: Nautilus Subsidiary, Inc.
    Inventors: Tural Aksel, Stephen Hendricks, Elvis Ikwa, Pierre Indermuhle, Sadie Ingle, Christina Inman, Parag Mallick, Torri Elise Rinker, Steven Tan
  • Publication number: 20230272459
    Abstract: An affinity reagent, having: (a) a retaining component such as a structured nucleic acid particle; and (b) one or both of (i) one or more label components attached to the retaining component, and (ii) one or more binding components attached to the retaining component.
    Type: Application
    Filed: March 7, 2023
    Publication date: August 31, 2023
    Inventors: Tural AKSEL, Torri RINKER, Markus BURNS, Michael DORWART, Rachel GALIMIDI, Dmitriy GREMYACHINSKIY, Stephen HENDRICKS, Elvis IKWA, Gregory KAPP, Joshua Simon KLEIN, Julia ROBINSON, Cassandra STAWICKI, Sonal TONAPI, Parag MALLICK
  • Patent number: 11692217
    Abstract: An affinity reagent, having: (a) a retaining component such as a structured nucleic acid particle; and (b) one or both of (i) one or more label components attached to the retaining component, and (ii) one or more binding components attached to the retaining component.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: July 4, 2023
    Assignee: Nautilus Subsidiary, Inc.
    Inventors: Tural Aksel, Torri Rinker, Markus Burns, Michael Dorwart, Rachel Galimidi, Dmitriy Gremyachinskiy, Stephen Hendricks, Elvis Ikwa, Gregory Kapp, Joshua Simon Klein, Julia Robinson, Cassandra Stawicki, Sonal Tonapi, Parag Mallick
  • Patent number: 11661629
    Abstract: Methods, assays, compositions and kits for the ligation of short polynucleotides are presented herein. The short polynucleotides are optionally no more than 7 nucleotides in length, and can be as short as 3 or 4 nucleotides in length. The ligation is optionally performed by CV ligase.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: May 30, 2023
    Assignee: Life Technologies Corporation
    Inventors: Stephen Hendricks, David J. King
  • Publication number: 20230112919
    Abstract: Compositions, systems, and methods for the display of analytes such as biomolecules are described. Display of analytes is achieved by coupling of the analytes to displaying molecules that are configured to associate with surfaces or interfaces. Arrays of analytes may be formed from the described systems for utilization in assays and other methods.
    Type: Application
    Filed: October 28, 2022
    Publication date: April 13, 2023
    Inventors: Tural AKSEL, Stephen HENDRICKS, Elvis IKWA, Pierre INDERMUHLE, Sadie INGLE, Christina INMAN, Parag MALLICK, Torri Elise RINKER, Steven TAN
  • Patent number: 11505796
    Abstract: Compositions, systems, and methods for the display of analytes such as biomolecules are described. Display of analytes is achieved by coupling of the analytes to displaying molecules that are configured to associate with surfaces or interfaces. Arrays of analytes may be formed from the described systems for utilization in assays and other methods.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: November 22, 2022
    Assignee: Nautilus Biotechnology, Inc.
    Inventors: Tural Aksel, Stephen Hendricks, Elvis Ikwa, Pierre Indermuhle, Sadie Ingle, Christina Inman, Parag Mallick, Torri Elise Rinker, Steven Tan
  • Publication number: 20220356236
    Abstract: The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 10, 2022
    Inventors: Chad Eric BIGELOW, Ana Maria CARRION, James Edgar CHASTAIN, Kirk Lee CLARK, Bijan Alexandre ETEMAD-GILBERTSON, Joy Gispati GHOSH, Shawn Michael HANKS, Nicole HAUBST, Ganesh Rajan IYER, Nina MOKER, Andrew Anh NGUYEN, Stephen Hendrick POOR, Yubin QIU, Nalini Velamur RANGASWAMY, Michael STEFANIDAKIS, Engin TOKSOZ, Michael Zbigniew TWAROG
  • Publication number: 20220348646
    Abstract: The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 3, 2022
    Inventors: Chad Eric BIGELOW, Ana Maria CARRION, James Edgar CHASTAIN, Kirk Lee CLARK, Bijan Alexandre ETEMAD-GILBERTSON, Joy Gispati GHOSH, Shawn Michael HANKS, Nicole HAUBST, Ganesh Rajan IYER, Nina MOKER, Andrew Anh NGUYEN, Stephen Hendrick POOR, Yubin QIU, Nalini Velamur RANGASWAMY, Michael STEFANIDAKIS, Engin TOKSOZ, Michael Zbigniew TWAROG
  • Publication number: 20220290130
    Abstract: Compositions, systems, and methods for the display of analytes such as biomolecules are described. Display of analytes is achieved by coupling of the analytes to displaying molecules that are configured to associate with surfaces or interfaces. Arrays of analytes may be formed from the described systems for utilization in assays and other methods.
    Type: Application
    Filed: March 10, 2022
    Publication date: September 15, 2022
    Inventors: Tural AKSEL, Stephen HENDRICKS, Elvis IKWA, Pierre INDERMUHLE, Sadie INGLE, Christina INMAN, Parag MALLICK, Torri Elise RINKER, Steven TAN
  • Publication number: 20220290218
    Abstract: Compositions, systems, and methods for the display of analytes such as biomolecules are described. Display of analytes is achieved by coupling of the analytes to displaying molecules that are configured to associate with surfaces or interfaces. Arrays of analytes may be formed from the described systems for utilization in assays and other methods.
    Type: Application
    Filed: March 14, 2022
    Publication date: September 15, 2022
    Inventors: Tural AKSEL, Stephen HENDRICKS, Pierre INDERMUHLE, Christina INMAN, Parag MALLICK, Hongji QIAN, Torri Elise RINKER, Steven TAN
  • Publication number: 20220162684
    Abstract: An affinity reagent, having: (a) a retaining component such as a structured nucleic acid particle; and (b) one or both of (i) one or more label components attached to the retaining component, and (ii) one or more binding components attached to the retaining component.
    Type: Application
    Filed: November 10, 2021
    Publication date: May 26, 2022
    Inventors: Tural AKSEL, Torri RINKER, Markus BURNS, Michael DORWART, Rachel GALIMIDI, Dmitriy GREMYACHINSKIY, Stephen HENDRICKS, Elvis IKWA, Gregory KAPP, Joshua KLEIN, Julia ROBINSON, Cassandra STAWICKI, Sonal TONAPI, Parag MALLICK
  • Publication number: 20220025032
    Abstract: The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.
    Type: Application
    Filed: July 14, 2021
    Publication date: January 27, 2022
    Inventors: Chad Eric BIGELOW, Ana Maria CARRION, James Edgar CHASTAIN, Kirk Lee CLARK, Bijan Alexandre ETEMAD-GILBERTSON, Joy Gispati GHOSH, Shawn Michael HANKS, Nicole HAUBST, Ganesh Rajan IYER, Nina MOKER, Andrew Anh NGUYEN, Stephen Hendrick POOR, Yubin QIU, Nalini Velamur RANGASWAMY, Michael STEFANIDAKIS, Engin TOKSOZ, Michael Zbigniew TWAROG
  • Publication number: 20210324460
    Abstract: This application relates to methods for ligating oligonucleotides having complementarity to a target nucleic acid, and amplifying the ligated oligonucleotides, where ligation and amplification occur in the same reaction mixture.
    Type: Application
    Filed: July 1, 2021
    Publication date: October 21, 2021
    Inventors: Shiaw-Min CHEN, Elana SWARTZMAN, David RUFF, Mark SHANNON, Julia LU, Stephen HENDRICKS
  • Patent number: 11072824
    Abstract: This application relates to methods for ligating oligonucleotides having complementarity to a target nucleic acid, and amplifying the ligated oligonucleotides, where ligation and amplification occur in the same reaction mixture.
    Type: Grant
    Filed: October 18, 2019
    Date of Patent: July 27, 2021
    Assignee: Life Technologies Corporation
    Inventors: Shiaw-Min Chen, Elana Swartzman, David Ruff, Mark Shannon, Julia Lu, Stephen Hendricks
  • Patent number: 10597705
    Abstract: In some embodiments, methods for ligating nucleic acid ends comprise: conducting a nucleic acid ligation reaction in the presence of at least one agent that generates a ligatable terminal 5? phosphate group by removing an adenylate group from a terminal 5? phosphate of a nucleic acid. In some embodiments, an aprataxin enzyme can catalyze removal of an adenylate group from a terminal 5? phosphate of a nucleic acid. In some embodiments, methods for ligating nucleic acid ends comprise: conducting a nucleic acid ligation reaction in the presence of an aprataxin enzyme under conditions suitable for ligating nucleic acid ends.
    Type: Grant
    Filed: October 8, 2018
    Date of Patent: March 24, 2020
    Assignee: Life Technologies Corporation
    Inventors: Stephen Hendricks, David King, Lei Xi, Marian Peris
  • Publication number: 20200048695
    Abstract: This application relates to methods for ligating oligonucleotides having complementarity to a target nucleic acid, and amplifying the ligated oligonucleotides, where ligation and amplification occur in the same reaction mixture.
    Type: Application
    Filed: October 18, 2019
    Publication date: February 13, 2020
    Inventors: Shiaw-Min CHEN, Elana SWARTZMAN, David RUFF, Mark SHANNON, Julia LU, Stephen HENDRICKS
  • Publication number: 20200048708
    Abstract: Methods, assays, compositions and kits for the ligation of short polynucleotides are presented herein. The short polynucleotides are optionally no more than 7 nucleotides in length, and can be as short as 3 or 4 nucleotides in length. The ligation is optionally performed by CV ligase.
    Type: Application
    Filed: October 28, 2019
    Publication date: February 13, 2020
    Inventors: Stephen HENDRICKS, David J. KING
  • Patent number: 10494671
    Abstract: Methods, assays, compositions and kits for the ligation of short polynucleotides are presented herein. The short polynucleotides are optionally no more than 7 nucleotides in length, and can be as short as 3 or 4 nucleotides in length. The ligation is optionally performed by CV ligase.
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: December 3, 2019
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Stephen Hendricks, David King
  • Patent number: 10472671
    Abstract: This application relates to methods for ligating oligonucleotides having complementarity to a target nucleic acid, and amplifying the ligated oligonucleotides, where ligation and amplification occur in the same reaction mixture.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: November 12, 2019
    Assignee: Life Technologies Corporation
    Inventors: Shiaw-Min Chen, Elana Swartzman, David Ruff, Mark Shannon, Julia Lu, Stephen Hendricks
  • Patent number: 10336991
    Abstract: Provided herein are mutant DNA-dependent polymerases which are derived from, or otherwise related to, wild type RB69 DNA polymerase. These mutant polymerases are capable of selectively binding labeled nucleotides. These mutant polymerases are also capable of incorporating a variety of naturally occurring and modified nucleotides, including, for example, terminator nucleotides.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: July 2, 2019
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Marian Peris, Michael Phelan, Barnett Rosenblum, Stephen Hendricks