Patents by Inventor Stephen Hoffman
Stephen Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11503819Abstract: Systems and methods for providing a combined mosquito staging and dissection system are disclosed. The system can include a mosquito staging subsystem; a robotic pick-and-place station; and a dissection, extrusion, collection, and disposal subsystem. The subsystems can include one or more stations to provide orientation, decapitation, extrusion of salivary glands, and disposal of carcasses of the mosquitoes. The resident live sporozoites from the salivary glands can be used to produce Plasmodium SPZ-based vaccines.Type: GrantFiled: August 17, 2020Date of Patent: November 22, 2022Assignees: Sanaria Inc., The Johns Hopkins UniversityInventors: Russell H. Taylor, Gregory Chirikjian, Iulian Iordachita, Henry Phalen, Hongtao Wu, Mengdi Xu, Shengnan Lu, Michael Aaron Pozin, Jin Seob Kim, Can Kocabalkanli, Balazs Vagvolgyi, Brian K. Chirikjian, Joshua Davis, Ting Da, John S. Chirikjian, Sumana Chakravarty, Stephen Hoffman
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Publication number: 20210253683Abstract: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.Type: ApplicationFiled: April 28, 2021Publication date: August 19, 2021Applicants: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC, Sanaria Inc.Inventors: Robert Seder, Neville Kisalu, Azza Idris, Barbara Flynn, Stephen Hoffman
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Patent number: 11021535Abstract: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.Type: GrantFiled: February 12, 2018Date of Patent: June 1, 2021Assignees: The United States of America as represented by the Secretary, Department of Health and Human Services, Sanaria Inc.Inventors: Robert Seder, Neville Kisalu, Azza Idris, Barbara Flynn, Stephen Hoffman
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Publication number: 20210045375Abstract: Systems and methods for providing a combined mosquito staging and dissection system are disclosed. The system can include a mosquito staging subsystem; a robotic pick-and-place station; and a dissection, extrusion, collection, and disposal subsystem. The subsystems can include one or more stations to provide orientation, decapitation, extrusion of salivary glands, and disposal of carcasses of the mosquitoes. The resident live sporozoites from the salivary glands can be used to produce Plasmodium SPZ-based vaccines.Type: ApplicationFiled: August 17, 2020Publication date: February 18, 2021Inventors: Russell H. TAYLOR, Gregory CHIRIKJIAN, Iulian IORDACHITA, Henry PHALEN, Hongtao WU, Mengdi XU, Shengnan LU, Michael Aaron POZIN, Jin Seob KIM, Can KOCABALKANLI, Balazs VAGVOLGYI, Brian K. CHIRIKJIAN, Joshua DAVIS, Ting DA, John S. CHIRIKJIAN, Sumana CHAKRAVARTY, Stephen HOFFMAN
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Publication number: 20200380482Abstract: The invention relates to an electronic exchange for bill pay transactions via an interbank information network (IIN) architecture. An embodiment of the present invention provides a marketplace for secure collection, assignment and distribution of payments and data from Bill Pay to Lockbox providers. This eliminates paper checks, resulting in faster deposit into client accounts, better management of payment exceptions, and reduction in overall operating costs. The IIN architecture provides a global platform using Blockchain technology for real-time interconnected flow of information that address immediate pain points across the financial industry and enable new services. With an embodiment of the present invention, a distributed network may streamline process for resolving compliance based inquiries and provide global beneficiary account validations.Type: ApplicationFiled: May 29, 2020Publication date: December 3, 2020Inventors: Stephen HOFFMAN, Sejdo Radoncic, Tiffany Ashley Wan, Amy M. Leslie, John L. Biloz, Raghvendra Singh
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Patent number: 10781419Abstract: A device and method of use for augmenting the extraction of salivary glands from Plasmodium-infected mosquitoes, where the sporozoite stage of Plasmodium primarily resides. Sporozoites are useful for research as well as for the immunogen in whole parasite vaccines for the prevention of malaria. The device and methods of use disclosed herein greatly increase the rate at which sporozoites can be harvested.Type: GrantFiled: June 13, 2017Date of Patent: September 22, 2020Assignees: Sanaria Inc., Johns Hopkins UniversityInventors: Russell H. Taylor, Amanda Canezin, Mariah Schrum, Iulian Iordachita, Gregory Chirikjian, Michelle Laskowski, Sumana Chakravarty, Stephen Hoffman
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Publication number: 20200258062Abstract: The invention relates to a system that implements an electronic exchange for bill pay transactions. The system comprises an electronic exchange network coupled to an electronic input, a memory component and a computer processor configured to perform the steps of: receiving electronic data files and payment files from a plurality of disparate bill payors; distributing data and funds to each participating lockbox provider file; creating an image of each transaction in the form of a non-negotiable check; creating image files for each lockbox provider participant from a plurality of lockbox provider participants, wherein each image file is indexed to each data file; consolidating image files, data files and payment files into an electronic package for each lockbox provider participant; and transmitting the electronic package to a respective lockbox provider participant.Type: ApplicationFiled: February 12, 2020Publication date: August 13, 2020Inventors: Stephen HOFFMAN, Sejdo RADONCIC, Tiffany Ashley WAN, Amy M. LESLIE, John L. BILOZ, Raghvendra SINGH
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Publication number: 20190375831Abstract: Antibodies and antigen binding fragments that specifically bind to P. falciparum circumsporozoite protein and neutralize P. falciparum are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. The disclosed antibodies, antigen binding fragments, nucleic acids and vectors can be used, for example, to inhibit a P. falciparum infection.Type: ApplicationFiled: February 12, 2018Publication date: December 12, 2019Applicants: HUMAN SERVICES, SANARIA INCInventors: Robert Seder, Neville Kisalu, Azza Idris, Barbara Flynn, Stephen Hoffman
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Publication number: 20170355951Abstract: A device and method of use for augmenting the extraction of salivary glands from Plasmodium-infected mosquitoes, where the sporozoite stage of Plasmodium primarily resides. Sporozoites are useful for research as well as for the immunogen in whole parasite vaccines for the prevention of malaria. The device and methods of use disclosed herein greatly increase the rate at which sporozoites can be harvested.Type: ApplicationFiled: June 13, 2017Publication date: December 14, 2017Inventors: Russell H. TAYLOR, Amanda CANEZIN, Mariah SCHRAM, lulian IORDACHITA, Gregory CHIRIKJIAN, Michelle LASKOWSKI, Sumana CHAKRAVARTY, Stephen HOFFMAN
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Patent number: 9642468Abstract: A seating unit having a foldable bed includes: a base with an internal cavity and a rear wall; a foldable bed that includes separate and distinct head, intermediate and seat sections, wherein in a folded position, the intermediate and seat sections are generally horizontally disposed and positioned in vertically stacked relationship, and the head section is generally vertically disposed and positioned adjacent the rear wall of the base, and in an unfolded position, the head, intermediate and seat sections are generally horizontally disposed and in serial alignment with each other; and a bed folding mechanism that is attached to the base and the head, intermediate and seat sections that controls the movement of the bed between the folded and unfolded positions.Type: GrantFiled: June 6, 2016Date of Patent: May 9, 2017Assignee: Ultra-Mek, Inc.Inventors: Marcus L. Murphy, D. Stephen Hoffman
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Patent number: 9603452Abstract: A reclining seating unit includes: a base; a seat having a seat frame; a gliding unit configured to allow the seat to reciprocate relative to the base; a backrest mounted and pivotally interconnected to the seat frame; a footrest unit; a reclining mechanism attached to the seat and the backrest, the reclining mechanism configured to control relative movement of the seat and backrest between upright and reclined positions; a footrest mechanism attached to the seat and the footrest unit, the footrest mechanism configured to control relative movement of the footrest unit and the seat between retracted and extended positions, the footrest mechanism being decoupled from the reclining mechanism; a first linear actuator attached to the reclining mechanism and to the seat configured to move the seat and backrest between the upright and reclined positions; and a second linear actuator attached to the footrest mechanism and to the seat frame configured to move the footrest unit between the retracted and extended positiType: GrantFiled: October 14, 2014Date of Patent: March 28, 2017Assignee: Ultra-Mek, Inc.Inventors: Marcus L. Murphy, D. Stephen Hoffman
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Patent number: 9603453Abstract: A reclining health-care chair includes: a base configured to rest on an underlying surface; a frame including a pair of opposed arms; a seat; a backrest; a footrest; a tilting mechanism comprising a plurality of pivotally interconnected links, the tilting mechanism attached to the base and to the seat and configured to control movement of the seat relative to the base; a reclining mechanism comprising a plurality of pivotally interconnected links, the reclining mechanism attached to the backrest, footrest, seat, frame and tilting mechanism to control relative movement of the backrest, footrest, frame and seat relative to the base; and a power actuating unit attached to the seat and to the tilting mechanism.Type: GrantFiled: December 28, 2011Date of Patent: March 28, 2017Assignee: Ultra-Mek, Inc.Inventors: D. Stephen Hoffman, Marcus L. Murphy
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Publication number: 20160353897Abstract: A seating unit having a foldable bed includes: a base with an internal cavity and a rear wall; a foldable bed that includes separate and distinct head, intermediate and seat sections, wherein in a folded position, the intermediate and seat sections are generally horizontally disposed and positioned in vertically stacked relationship, and the head section is generally vertically disposed and positioned adjacent the rear wall of the base, and in an unfolded position, the head, intermediate and seat sections are generally horizontally disposed and in serial alignment with each other; and a bed folding mechanism that is attached to the base and the head, intermediate and seat sections that controls the movement of the bed between the folded and unfolded positions.Type: ApplicationFiled: June 6, 2016Publication date: December 8, 2016Inventors: Marcus L. Murphy, D. Stephen Hoffman
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Patent number: 9357850Abstract: A seating unit having a foldable bed includes: a base with an internal cavity and a rear wall; a foldable bed that includes separate and distinct head, intermediate and seat sections, wherein in a folded position, the intermediate and seat sections are generally horizontally disposed and positioned in vertically stacked relationship, and the head section is generally vertically disposed and positioned adjacent the rear wall of the base, and in an unfolded position, the head, intermediate and seat sections are generally horizontally disposed and in serial alignment with each other; and a bed folding mechanism that is attached to the base and the head, intermediate and seat sections that controls the movement of the bed between the folded and unfolded positions.Type: GrantFiled: August 20, 2015Date of Patent: June 7, 2016Assignee: Ultra-Mek, Inc.Inventors: Marcus L. Murphy, D. Stephen Hoffman
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Publication number: 20160100687Abstract: A reclining seating unit includes: a base; a seat having a seat frame; a gliding unit configured to allow the seat to reciprocate relative to the base; a backrest mounted and pivotally interconnected to the seat frame; a footrest unit; a reclining mechanism attached to the seat and the backrest, the reclining mechanism configured to control relative movement of the seat and backrest between upright and reclined positions; a footrest mechanism attached to the seat and the footrest unit, the footrest mechanism configured to control relative movement of the footrest unit and the seat between retracted and extended positions, the footrest mechanism being decoupled from the reclining mechanism; a first linear actuator attached to the reclining mechanism and to the seat configured to move the seat and backrest between the upright and reclined positions; and a second linear actuator attached to the footrest mechanism and to the seat frame configured to move the footrest unit between the retracted and extended positiType: ApplicationFiled: October 14, 2014Publication date: April 14, 2016Inventors: Marcus L. Murphy, D. Stephen Hoffman
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Publication number: 20150351554Abstract: A seating unit having a foldable bed includes: a base with an internal cavity and a rear wall; a foldable bed that includes separate and distinct head, intermediate and seat sections, wherein in a folded position, the intermediate and seat sections are generally horizontally disposed and positioned in vertically stacked relationship, and the head section is generally vertically disposed and positioned adjacent the rear wall of the base, and in an unfolded position, the head, intermediate and seat sections are generally horizontally disposed and in serial alignment with each other; and a bed folding mechanism that is attached to the base and the head, intermediate and seat sections that controls the movement of the bed between the folded and unfolded positions.Type: ApplicationFiled: August 20, 2015Publication date: December 10, 2015Inventors: Marcus L. Murphy, D. Stephen Hoffman
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Patent number: 9149121Abstract: A gliding reclining seating unit includes: a base; a frame with opposed arms; a gliding mechanism attached to the frame and the base, the gliding mechanism configured to enable the frame to glide longitudinally relative to the base; a seat; a backrest; an ottoman; a reclining mechanism comprising a plurality of pivotally interconnected links and attached to the frame, seat, backrest and ottoman, the reclining mechanism being configured to move the seating unit between an upright position, an intermediate TV position, and (c) a fully reclined position; and a glide stop unit that prevents the frame from gliding rearwardly relative to the base when the seating unit is in the TV and fully reclined positions. The seating unit is actuated for movement from the upright position to the TV position via an occupant of the chair pushing on the arms of the frame.Type: GrantFiled: February 6, 2012Date of Patent: October 6, 2015Assignee: Ultra-Mek, Inc.Inventors: D. Stephen Hoffman, Marcus L. Murphy
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Patent number: 9144319Abstract: A seating unit having a foldable bed includes: a base with an internal cavity and a rear wall; a foldable bed that includes separate and distinct head, intermediate and seat sections, wherein in a folded position, the intermediate and seat sections are generally horizontally disposed and positioned in vertically stacked relationship, and the head section is generally vertically disposed and positioned adjacent the rear wall of the base, and in an unfolded position, the head, intermediate and seat sections are generally horizontally disposed and in serial alignment with each other; and a bed folding mechanism that is attached to the base and the head, intermediate and seat sections that controls the movement of the bed between the folded and unfolded positions.Type: GrantFiled: February 5, 2014Date of Patent: September 29, 2015Assignee: Ultra-Mek, Inc.Inventors: Marcus L. Murphy, D. Stephen Hoffman
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Publication number: 20150135432Abstract: A seating unit having a foldable bed includes: a base with an internal cavity and a rear wall; a foldable bed that includes separate and distinct head, intermediate and seat sections, wherein in a folded position, the intermediate and seat sections are generally horizontally disposed and positioned in vertically stacked relationship, and the head section is generally vertically disposed and positioned adjacent the rear wall of the base, and in an unfolded position, the head, intermediate and seat sections are generally horizontally disposed and in serial alignment with each other; and a bed folding mechanism that is attached to the base and the head, intermediate and seat sections that controls the movement of the bed between the folded and unfolded positions.Type: ApplicationFiled: February 5, 2014Publication date: May 21, 2015Applicant: ULTRA-MEK, INC.Inventors: Marcus L. Murphy, D. STEPHEN HOFFMAN
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Patent number: 8997273Abstract: A seating unit that includes a foldable bed includes: a base with an internal cavity; a foldable bed that includes a plurality of sections, wherein in a folded position, the bed sections are folded relative to each other and stored within the base cavity, and in an unfolded position, the bed sections are generally horizontally disposed and in serial alignment with each other, with a first bed section being positioned forwardly of the base; a bed folding mechanism that is attached to the base and the bed sections that controls the movement of the bed between the folded and unfolded positions; a foldable leg attached to the first bed section, and a leg folding mechanism attached to the leg and the first bed section configured to extend the leg downwardly from the first bed section when the bed is in the unfolded position, and to fold the leg under the first bed section when the bed is in the folded position, the leg being pivotable about an axis that is parallel with the forward direction.Type: GrantFiled: May 22, 2013Date of Patent: April 7, 2015Assignee: Ultra-Mek, Inc.Inventors: Marcus L. Murphy, D. Stephen Hoffman