Patents by Inventor Stephen J Brand

Stephen J Brand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment for diabetes using a gastrin/CCK receptor ligand and an EGF receptor ligand
    Patent number: 5885956
    Abstract: A method for treating diabetes mellitus by administering composition providing a gastrin/CCK receptor ligand, e.g. a gastrin, and an EGF receptor ligand, e.g. TGF.alpha., in an amount sufficient to effect differentiation of pancreatic islet precursor cells to mature insulin-secreting cells. The composition can be administered systemically or expressed in situ by cells transgenically supplemented with one or both of a gastrin/CCK receptor ligand gene, e.g. a preprogastrin peptide precursor gene and an EGF receptor ligand gene, e.g. a TGF.alpha. gene.
    Type: Grant
    Filed: December 14, 1992
    Date of Patent: March 23, 1999
    Assignees: Research Triangle Pharmaceuticals, The General Hospital Corporation
    Inventors: Ronald V. Nardi, Stephen J. Brand