Patents by Inventor Stephen J. Libby

Stephen J. Libby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and host cells for recombinant protein expression
    Patent number: 8247195
    Abstract: Methods for expressing recombinant polypeptides in host cells and host cells for polypeptide expression are provided.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: August 21, 2012
    Assignee: The University of Washington
    Inventors: Ferric C. Fang, William Wiley Navarre, Stephen J. Libby
  • METHODS AND HOST CELLS FOR RECOMBINANT PROTEIN EXPRESSION
    Publication number: 20080299617
    Abstract: Methods for expressing recombinant polypeptides in host cells and host cells for polypeptide expression are provided.
    Type: Application
    Filed: January 16, 2008
    Publication date: December 4, 2008
    Inventors: Ferric C. Fang, William Wiley Navarre, Stephen J. Libby
  • Cytolysin gene and gene product
    Patent number: 5525504
    Abstract: A Salmonella gene, encoding a cytolysin, has been identified by screening for hemolysis on blood agar. The gene (slyA) is present in every strain of Salmonella examined in Shigella, and enteroinvasive Escherichia coli (EIEC) but not in other enterobacteriaceae. It is encoded near 28.5 minutes on the chromosome. A SlyA (salmolysin) has hemolytic and cytolytic activity and has a molecular weight predicted by the DNA sequence. LD.sub.50 and infection kinetics data in mice indicate that the toxin is required for virulence and facilitates Salmonella survival within peritoneal macrophages.
    Type: Grant
    Filed: April 30, 1993
    Date of Patent: June 11, 1996
    Assignee: Merck Patent Gesellschaft mit beschrankter Haftung
    Inventors: Werner Goebel, Stephen J. Libby, Fred Heffron