Patents by Inventor Stephen J. Shimshock

Stephen J. Shimshock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXCR2 inhibitors
    Patent number: 8283479
    Abstract: The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
    Type: Grant
    Filed: April 4, 2011
    Date of Patent: October 9, 2012
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Stephanie Hachtel, Juergen Dedio, Holger Heitsch, Werngard Czechtizky, Sven Grueneberg, Stephen J. Shimshock, Raymond W. Kosley, Jr., Carolina L. Lanter, Hui Li, Rosy Sher, Aleksandra Weichsel
  • CXCR2 INHIBITORS
    Publication number: 20110184177
    Abstract: The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
    Type: Application
    Filed: April 4, 2011
    Publication date: July 28, 2011
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Stephanie Hachtel, Juergen Dedio, Holger Heitsch, Werngard Czechtizky, Sven Grueneberg, Stephen J. Shimshock, Raymond W. Kosley, JR., Carolina L. Lanter, Hui Li, Rosy Sher, Aleksandra Weichsel
  • CXCR2 inhibitors
    Patent number: 7919628
    Abstract: The invention relates to compounds of the formula I: in which R1, R2, X, A, B, D and Y1 to Y4 have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: April 5, 2011
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Stephanie Hachtel, Juergen Dedio, Holger Heitsch, Werngard Czechtizky, Sven Grueneberg, Stephen J. Shimshock, Raymond W. Kosley, Jr., Carolina L. Lanter, Hui Li, Rosy Sher, Aleksandra Weichsel
  • N-sulfonylpipecolic acid derivative FKBP binding composition and pharmaceutical use thereof
    Patent number: 7777042
    Abstract: A composition for binding FKBP proteins is disclosed, along with a method of treating conditions associated with neuronal degeneration, wherein said composition comprises a compound of formula I, wherein, R, R1, R2, R3 and X are as defined herein.
    Type: Grant
    Filed: December 6, 2006
    Date of Patent: August 17, 2010
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Bruce Baron, Patrick Jimonet, John G. Jurcak, Stephen J. Shimshock, Xu-Yang Zhao, Rosy Sher, Paul J. Mueller, Jennifer Beall, Matthieu Barrague, Joseph W. Guiles
  • FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF
    Publication number: 20080139556
    Abstract: A composition for binding FKBP proteins is disclosed, along with a method of treating conditions associated with neuronal degeneration, wherein said composition comprises a compound of formula I, wherein, R, R1, R2, R3 and X are as defined herein.
    Type: Application
    Filed: December 6, 2006
    Publication date: June 12, 2008
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: Raymond W. KOSLEY, Bruce Baron, Patrick Jimonet, John G. Jurcak, Stephen J. Shimshock, Xu-yang Zhao, Rosy Sher, Paul J. Mueller, Jennifer Beall, Matthieu Barrague, Joseph W. Guiles
  • Substituted amides, sulfonamides and ureas useful for inhibiting kinase activity
    Publication number: 20030087832
    Abstract: Amide, sulfonamide and urea compounds having an inhibitory effect on Src kinase including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formulae I and II: 1
    Type: Application
    Filed: July 9, 2002
    Publication date: May 8, 2003
    Inventors: Pavel Safar, Armin Walser, Stephen J. Shimshock
  • Aminoalkylphenol derivatives and related compounds
    Patent number: 6479495
    Abstract: Novel aminoalkylphenols, intermediates and processes for the preparation thereof, and methods of relieving memory dysfunction utilizing the aminoalkylphenols or compositions thereof are disclosed.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: November 12, 2002
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Raymond W. Kosley, Jr., Mark G. Palermo, Stephen J. Shimshock, Veronica Wolf
  • Isatin derivatives as acetylcholinesterase inhibitors and analgesics
    Patent number: 6100276
    Abstract: This application relates to compounds of the formula ##STR1## wherein R, X and Y are defined within, which compounds are useful for the treatment of memory dysfunction characterized by decreased cholinergic function, and for analgesia, pharmaceutical compositions containing the compounds and methods for making and using the compounds.
    Type: Grant
    Filed: February 24, 1997
    Date of Patent: August 8, 2000
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Stephen J. Shimshock, Susan M. Chesson, Abdul E. Mutlib