Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: A fragrance system for a room, building or other environment, the system including (a) a stand or other form of base and (b) one or more portable fragrance objects, each portable fragrance object providing a fragrance and configured to rest on the stand or base. The stand or base includes one or more fans or other air movement system arranged to release fragrance from one or more of the fragrance objects.

Abstract: Disclosed are systems and methods for improving condensate recovery. A first stripping vapor is injected into a condensate fractionator tower. Introducing the first stripping vapor into the condensate fractionator tower allows for an operating temperature of the condensate fractionator tower to be decrease while achieve a required condensate recovery rate. The condensate fractionator tower further separates a condensate product from a light oil product and directs the condensate product and light oil product to storage.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: The present invention relates to an electrical nerve stimulator configured to deliver an electrical signal to a user to entrain Mu-band neural oscillations and/or Beta-band neural oscillations. The electrical nerve stimulator may be used in the treatment of neurological conditions associated with desynchronization of neural oscillations, such as Tourette's syndrome. The electrical nerve stimulator may be wearable on a wrist of a user, and may be configured to deliver rhythmic stimulation at a frequency falling within the same frequency range of Mu-band or Beta-band neural oscillations. The invention provides a convenient means of treating conditions such as Tourette's syndrome without the need for specialist medical equipment or facilities. Also disclosed is a method of delivering an electrical signal to a user to entrain Mu-band neural oscillations and/or Beta-band neural oscillations.

Abstract: An article and related apparatus and methods for an aerosol provision system, including: a storage area for aerosol-generating material; an inlet orifice in fluid communication with an interior of the storage area by which aerosol-generating material can be added into the storage area; a first capacitive sensor including a first pair of capacitor plates arranged to measure a capacitance of the storage area; a second capacitive sensor including a second pair of capacitor plates arranged to measure a capacitance of the storage area; and electrical contacts by which capacitance measurements made by the first capacitive sensor and the second capacitive sensor can be separately ascertained externally to the article.

Abstract: In some implementations, the techniques may include at a first time: performing, using a first sensor, a first ranging measurement with a second device to obtain a first distance; and performing, using a second sensor, a first altitude measurement to obtain a first altitude. In addition, the techniques may include at a second time: performing, using the first sensor, a second ranging measurement with the second device to obtain a second distance; and performing, using the second sensor, a second altitude measurement to obtain a second altitude. The techniques may include determining a ranging difference between the first distance and the second distance. Moreover, the techniques may include determining an altitude difference between the first altitude and the second altitude. Also, the techniques may include determining whether the second device is on a different floor of a building than the first device.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: A vaping system includes: (a) a disposable vaping device that includes the following non user-replaceable items: (i) a heating element; (ii) a rechargeable battery, and (iii) a liquid reservoir that provides liquid to the heating element; and (b) an automatic liquid filling device, including (i) a first aperture or port configured to receive a liquid bottle or container containing atomisable liquid; (ii) a second aperture or port configured to receive the vaping device; (iii) an electronic liquid level sensing sub-system; (iv) a liquid filling sub-system configured to pump liquid from the liquid bottle or container to the liquid reservoir in the vaping device and (v) a battery charging sub-system.

Abstract: The present invention relates to an electrical nerve stimulator configured to deliver an electrical signal to a user to entrain Mu-band neural oscillations and/or Beta-band neural oscillations. The electrical nerve stimulator may be used in the treatment of neurological conditions associated with desynchronization of neural oscillations, such as Tourette's syndrome. The electrical nerve stimulator may be wearable on a wrist of a user, and may be configured to deliver rhythmic stimulation at a frequency falling within the same frequency range of Mu-band or Beta-band neural oscillations. The invention provides a convenient means of treating conditions such as Tourette's syndrome without the need for specialist medical equipment or facilities. Also disclosed is a method of delivering an electrical signal to a user to entrain Mu-band neural oscillations and/or Beta-band neural oscillations.

Abstract: A reservoir for use in a refilling device includes a fluid storage volume bounded by one or more side walls and an end wall; an outlet orifice in or near the end wall, configured to form, or engage with, a fluid conduit engagable with an inlet orifice of an article of an aerosol provision system to provide a fluid flow path from the fluid storage volume to a storage area in the article when the reservoir and the article are installed in the refilling device; and a moveable wall disposed opposite to the end wall to close the fluid storage volume, the movable wall configured to slide towards the end wall, and engagable with a pushing element of the refilling device operable to push the moveable wall towards the end wall in order to reduce a capacity of the fluid storage volume such that fluid in the fluid storage volume is moved through the outlet orifice to the fluid flow path in order to fill the storage area of the article.

Abstract: The present invention relates to the recognition that inhibition of the base excision repair pathway is selectively lethal in cells which are deficient in HR dependent DNA DSB repair. Methods and means relating to the treatment of cancers which are deficient in HR dependent DNA DSB repair using inhibitors which target base excision repair components, such as PARP, is provided herein.

Abstract: The present invention provides compounds of formula (I) wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.

Abstract: The present invention provides compounds of formula (I) wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.

Abstract: A computer implemented system and method for quantifying a risk associated with medical and health care, the steps of which have; calculating, via a processor, a first value; the first value equal to the medications prescribed to a plurality of individuals in a specified population; calculating, via a processor, a second value; the second value equal to the prescribers of the first value of the plurality of individuals in a specified population; calculating, via a processor, a third value; the third value equal to the associated therapeutic classifications of the first value of the plurality of individuals in a specified population; calculating, via a processor, an average value of each first, second and third value; comparing, via a processor, the average value of each first, second and third value against a fourth value; the fourth value equal to a single individual of the first, second and third value; transforming, via a processor, the first, second, third and fourth values into a fifth value, calculating

Abstract: The present invention provides compounds of formula (I) wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as medicaments for the treatment of diseases and infections caused by Acinetobacter baumannii.