Patents by Inventor Stephen James Russell

Stephen James Russell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treating type I and type II diabetes
    Patent number: 10947291
    Abstract: This document provides methods and materials for treating diabetes. For example, methods and materials for using nucleic acid encoding human preproinsulin to treat diabetes (e.g., type I or type II diabetes) are provided.
    Type: Grant
    Filed: February 14, 2018
    Date of Patent: March 16, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Stephen James Russell
  • FOAMY VIRUSES AND METHODS OF USE
    Publication number: 20210046134
    Abstract: This document provides methods and materials for treating cancer. For example, foamy viruses (e.g., simian foamy viruses) are provided as well as methods and materials for treating cancer using foamy viruses as an oncolytic agent.
    Type: Application
    Filed: April 12, 2019
    Publication date: February 18, 2021
    Inventors: Yasuhiro Ikeda, Karol M. Budzik, Stephen James Russell
  • Treating cancer with viral nucleic acid
    Patent number: 10913775
    Abstract: This document provides methods and materials related to the use of nucleic acid coding for viruses to reduce the number of viable cancer cells within a mammal. For example, methods for using infectious nucleic acid to treat cancer, engineered viral nucleic acid, methods for making engineered viral nucleic acid, methods for identifying infectious nucleic acid for treating cancer, methods and materials for controlling virus-mediated cell lysis, and methods and materials for assessing the control of virus-mediated cell lysis are provided.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: February 9, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Elizabeth J. Kelly, Elizabeth M. Hadac
  • USING INFECTIOUS NUCLEIC ACID TO TREAT CANCER
    Publication number: 20200405791
    Abstract: This document provides methods and materials related to using infectious nucleic acid encoding viruses to reduce the number of viable cancer cells within a mammal. For example, methods for using infectious nucleic acid to treat cancer, engineered viral nucleic acid, and methods for making engineered viral nucleic acid are provided.
    Type: Application
    Filed: March 12, 2019
    Publication date: December 31, 2020
    Inventors: Autumn J. SCHULZE, Stephen James RUSSELL, Noura B. ELSEDAWY
  • VESICULAR STOMATITIS VIRUSES
    Publication number: 20200325204
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, vesicular stomatitis viruses, nucleic acid molecules encoding VSV polypeptides, methods for making vesicular stomatitis viruses, and methods for using vesicular stomatitis viruses to treat cancer are provided.
    Type: Application
    Filed: June 30, 2020
    Publication date: October 15, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Shruthi Naik
  • Vesicular stomatitis viruses
    Patent number: 10752666
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, vesicular stomatitis viruses, nucleic acid molecules encoding VSV polypeptides, methods for making vesicular stomatitis viruses, and methods for using vesicular stomatitis viruses to treat cancer are provided.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: August 25, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Shruthi Naik
  • MUMPS VIRUS AS A POTENTIAL ONCOLYTIC AGENT
    Publication number: 20200224175
    Abstract: This document relates to methods and materials for virotherapy. For example, this document provides methods and materials for treating cancer using a recombinant mumps virus as an oncolytic agent.
    Type: Application
    Filed: January 21, 2020
    Publication date: July 16, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Mark J. Federspiel, Arun Ammayappan, Gennett Pike, Stephen James Russell
  • REPLICATION-COMPETENT VESICULAR STOMATITIS VIRUSES
    Publication number: 20200206286
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Application
    Filed: March 3, 2020
    Publication date: July 2, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • MODIFIED VIRUSES
    Publication number: 20200147204
    Abstract: This document relates to methods and materials for making and using viruses (e.g., measles viruses or adenoviruses) having a reduced susceptibility to antibody neutralization (e.g., antibody neutralization by serum from measles virus vaccines). For example, recombinant morbilliviruses (e.g., recombinant measles viruses) having a modified H gene and a modified F gene, as well as methods of using a recombinant virus are provided.
    Type: Application
    Filed: April 4, 2018
    Publication date: May 14, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Miguel A. Munoz Alia, Stephen James Russell
  • Replication-competent vesicular stomatitis viruses
    Patent number: 10610553
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: April 7, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • Mumps virus as a potential oncolytic agent
    Patent number: 10577591
    Abstract: This document relates to methods and materials for virotherapy. For example, this document provides methods and materials for treating cancer using a recombinant mumps virus as an oncolytic agent.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: March 3, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Mark J. Federspiel, Arun Ammayappan, Gennett Pike, Stephen James Russell
  • METHODS AND MATERIALS FOR TREATING CANCER
    Publication number: 20190328805
    Abstract: This document relates to methods and materials involved in treating cancer. For example, methods and materials for using one or more oncolytic viruses (e.g., one or more replicating oncolytic viruses) to treat cancer in a mammal (e.g., a human) identified as having a cancer likely to respond to oncolytic virotherapy are provided.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 31, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Mitesh J. Borad, Yumei Zhou, Amber C. Miller
  • TARGETING PD-L1 ON TUMOR CELLS
    Publication number: 20190169296
    Abstract: This document relates to materials and methods for treating cancer. For example, this document provides materials and methods for using PD-L1 targeting domains in bispecific chimeric polypeptides, chimeric transmembrane polypeptides, genetically modified viruses, nucleic acid vectors, and/or fusion-inducing cells to treat cancer.
    Type: Application
    Filed: May 18, 2017
    Publication date: June 6, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James RUSSELL, Autumn J. RUIZ, Arun AMMAYAPPAN, Kah-Whye PENG, Camilo Ayala BRETON
  • TREATING CARDIOVASCULAR OR RENAL DISEASES
    Publication number: 20180369338
    Abstract: This document provides methods and materials for treating cardiovascular and/or renal diseases. For example, AAV9 vectors designed to express natriuretic polypeptides, nucleic acid molecules encoding natriuretic polypeptides, methods for making AAV9 vectors, and methods for using such vectors or molecules to treat cardiovascular and/or renal diseases are provided.
    Type: Application
    Filed: September 6, 2018
    Publication date: December 27, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Yasuhiro Ikeda, Stephen James Russell, Alessandro Cataliotti, John C. Burnett, Jr., Jason M. Tonne
  • Treating cardiovascular or renal diseases
    Patent number: 10092628
    Abstract: This document provides methods and materials for treating cardiovascular and/or renal diseases. For example, AAV9 vectors designed to express natriuretic polypeptides, nucleic acid molecules encoding natriuretic polypeptides, methods for making AAV9 vectors, and methods for using such vectors or molecules to treat cardiovascular and/or renal diseases are provided.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: October 9, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Yasuhiro Ikeda, Stephen James Russell, Alessandro Cataliotti, John C. Burnett, Jr., Jason M. Tonne
  • TREATING CARDIOVASCULAR OR RENAL DISEASES
    Publication number: 20180243378
    Abstract: This document provides methods and materials for treating cardiovascular and/or renal diseases. For example, AAV9 vectors designed to express natriuretic polypeptides, nucleic acid molecules encoding natriuretic polypeptides, methods for making AAV9 vectors, and methods for using such vectors or molecules to treat cardiovascular and/or renal diseases are provided.
    Type: Application
    Filed: April 30, 2018
    Publication date: August 30, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Yasuhiro Ikeda, Stephen James Russell, Alessandro Cataliotti, John C. Burnett, Jr., Jason M. Tonne
  • VESICULAR STOMATITIS VIRUSES
    Publication number: 20180237492
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, vesicular stomatitis viruses, nucleic acid molecules encoding VSV polypeptides, methods for making vesicular stomatitis viruses, and methods for using vesicular stomatitis viruses to treat cancer are provided.
    Type: Application
    Filed: March 19, 2018
    Publication date: August 23, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Shruthi Naik
  • TREATING CANCER WITH VIRAL NUCLEIC ACID
    Publication number: 20180215794
    Abstract: This document provides methods and materials related to the use of nucleic acid coding for viruses to reduce the number of viable cancer cells within a mammal. For example, methods for using infectious nucleic acid to treat cancer, engineered viral nucleic acid, methods for making engineered viral nucleic acid, methods for identifying infectious nucleic acid for treating cancer, methods and materials for controlling virus-mediated cell lysis, and methods and materials for assessing the control of virus-mediated cell lysis are provided.
    Type: Application
    Filed: March 27, 2018
    Publication date: August 2, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Elizabeth J. Kelly, Elizabeth M. Hadac
  • REPLICATION-COMPETENT VESICULAR STOMATITIS VIRUSES
    Publication number: 20180214497
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Application
    Filed: January 8, 2018
    Publication date: August 2, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • TREATING TYPE I AND TYPE II DIABETES
    Publication number: 20180186854
    Abstract: This document provides methods and materials for treating diabetes. For example, methods and materials for using nucleic acid encoding human preproinsulin to treat diabetes (e.g., type I or type II diabetes) are provided.
    Type: Application
    Filed: February 14, 2018
    Publication date: July 5, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Stephen James Russell