Patents by Inventor Stephen John Clifford Taylor

Stephen John Clifford Taylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme-mediated synthesis of peptidomimetics
    Patent number: 6436697
    Abstract: A process for the preparation of a compound of formula (1) comprises reacting compounds of formulae (2) and (3) in the presence of an enzyme, wherein A is a thiol-protecting group, B, C and D are each the same or different organic groups of up to 30 C atoms, optionally functionalized at any position, provided that neither a primary amine nor a primary amide is present, and X is a group that can be displaced by NH2.
    Type: Grant
    Filed: October 22, 1999
    Date of Patent: August 20, 2002
    Assignee: Darwin Discovery, Ltd.
    Inventors: Karen Holt, Stephen John Clifford Taylor, Peter David Tiffin
  • Cyclisation process
    Patent number: 6333418
    Abstract: There is provided a process for the cyclisation of 4-amino-2-halobutyric acid to azetidine-2-carboxylic acid wherein more than 20 g of 4-amino-2-halobutyric acid is cyclised per liter of reaction mixture.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: December 25, 2001
    Assignee: AstraZeneca AB
    Inventors: Julian Simon Parratt, Stephen John Clifford Taylor
  • Preparation of chiral cycloalkanols such as endo-5-norbornen-2-ol
    Patent number: 6075156
    Abstract: A cycloalkanol is prepared by cycloaddition between a diene and a vinyl ester, wherein the ester is derived from a carboxylic acid of sufficient molecular weight to enable the reaction to be carried out at atmospheric pressure while above 150.degree. C., and the corresponding reaction between the diene and vinyl acetate generates a pressure above 4 atmospheres.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: June 13, 2000
    Assignee: Chirotech Technology Limited
    Inventors: Stephen John Clifford Taylor, Raymond McCague, Derek Thomas Edward Jones
  • Process for the separation of the enantiomers of a bicyclic lactam
    Patent number: 5898075
    Abstract: A process is described for obtaining a single enantiomer from a racemic mixture of the bicyclic lactam 2-azabicyclo?2.2. 1! hept-5-en-one by seeding a supersaturated solution of the lactam and a solvent with a single enantiomer of the lactam.
    Type: Grant
    Filed: March 13, 1997
    Date of Patent: April 27, 1999
    Assignee: Chirotech Technology Limited
    Inventors: Raymond McCague, Gerard Andrew Potter, Stephen John Clifford Taylor, Brian Michael Adger
  • Chiral compounds and their resolution synthesis using enantioselective esterases
    Patent number: 5661014
    Abstract: Enantiomeric glutarimides such as aminoglutethimide and rogletimide are prepared by cyclisation of a corresponding ester-nitrile which is a good substrate for biotransformation with an enantiospecific esterase.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: August 26, 1997
    Assignee: Chiroscience Limited
    Inventors: Christopher Thomas Evans, Raymond McCague, Stephen John Clifford Taylor