Patents by Inventor Stephen John Freese

Stephen John Freese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for preparing serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
    Patent number: 9623100
    Abstract: The present invention relates to immunogenic conjugates comprising S. aureus serotype 5 and 8 capsular polysaccharides conjugated to carrier proteins and methods for their preparation and use. Methods for making the immunogenic conjugates of the invention involve covalent conjugation of the capsular polysaccharides with the carrier proteins using conjugation chemistry involving either 1,1-carbonyl-di-1,2,4-triazole (CDT) or 3-(2-pyridyldithio)-propionyl hydrazide (PDPH).
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: April 18, 2017
    Assignee: Wyeth LLC
    Inventors: Stephen John Freese, Annaliesa Anderson, Viliam Pavliak, Kathrin Ute Jansen, Ingrid Lea Scully, Tracy Dee Scott, Jasdeep Singh Nanra, A. Krishna Prasad, Bruce Arthur Green
  • COMPOSITIONS AND METHODS FOR PREPARING STAPHYLOCOCCUS AUREUS SEROTYPE 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE IMMUNOGENIC COMPOSITIONS
    Publication number: 20160022798
    Abstract: The present invention relates to immunogenic conjugates comprising S. auerus serotype 5 and 8 capsular polysaccharides conjugated to carrier proteins and methods for their preparation and use. Methods for making the immunogenic conjugates of the invention involve covalent conjugation of the capsular polysaccharides with the carrier proteins using conjugation chemistry involving either 1,1-carboyl-di-1,2,4-triazole (CDT) or 3-(2-pyridyldithio)-propionyl hydrazide (PDPH).
    Type: Application
    Filed: July 28, 2015
    Publication date: January 28, 2016
    Inventors: Stephen John Freese, Annaliesa Anderson, Viliam Pavliak, Kathrin Ute Jansen, Ingrid Lea Scully, Tracy Dee Scott, Jasdeep Singh Nanra, A. Krishna Prasad, Bruce Arthur Green
  • Compositions and methods for preparing serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
    Patent number: 9125951
    Abstract: The present invention relates to immunogenic conjugates comprising S. aureus serotype 5 and 8 capsular polysaccharides conjugated to carrier proteins and methods for their preparation and use. Methods for making the immunogenic conjugates of the invention involve covalent conjugation of the capsular polysaccharides with the carrier proteins using conjugation chemistry involving either 1,1-carboyl-di-1,2,4-triazole (CDT) or 3-(2-pyridyldithio)-propionyl hydrazide (PDPH).
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: September 8, 2015
    Assignee: Wyeth LLC
    Inventors: Stephen John Freese, Annaliesa Anderson, Viliam Pavliak, Kathrin Ute Jansen, Ingrid Lea Scully, Tracy Dee Scott, Jasdeep Singh Nanra, A. Krishna Prasad, Bruce Arthur Green
  • COMPOSITIONS AND METHODS FOR PREPARING STAPHYLOCOCCUS AUREUS SEROTYPE 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE IMMUNOGENIC COMPOSITIONS
    Publication number: 20120276137
    Abstract: The present invention relates to immunogenic conjugates comprising S. aureus serotype 5 and 8 capsular polysaccharides conjugated to carrier proteins and methods for their preparation and use. Methods for making the immunogenic conjugates of the invention involve covalent conjugation of the capsular polysaccharides with the carrier proteins using conjugation chemistry involving either 1,1-carboyl-di-1,2,4-triazole (CDT) or 3-(2-pyridyldithio)-propionyl hydrazide (PDPH).
    Type: Application
    Filed: June 22, 2010
    Publication date: November 1, 2012
    Applicant: Wyeth LLC
    Inventors: Stephen John Freese, Annaliesa Anderson, Viliam Pavliak, Kathrin Ute Jansen, Ingrid Lea Scully, Tracy Dee Scott, Jasdeep Singh Nanra, A. Krishna Prasad, Bruce Arthur Green