Abstract: The present invention relates to a compound according to general formula (I) wherein X represents N or CH; R1 is —CN, (C1-C6)alkyl, (C3-C7)cycloalkyl, (3-7 membered)heterocycloalkyl, (5-6 membered)heteroaryl, (C3-C7)cycloalkyl(C1-C4)alkyl, (3-7 membered)heterocycloalkyl-(C1-C4)alkyl or (5-6 membered)heteroaryl-(C1-C4)alkyl; R2 is halogen, cyano, (C1-C4)alkyl or (C3-C7)cycloalkyl; R3 is halogen, cyano, (C1-C4)alkyl, (C1-C4)haloalkyl or (C3-C7)cycloalkyl; R4 is (C1-C4)alkyl or (C1-C4)haloalkyl; R5 is (C1-C6)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkyl-(C3-C7)cycloalkyl, (C3-C7)cycloalkyl-(C1-C6)alkyl, (3-7 membered)heterocycloalkyl, phenyl, (5-6 membered)heteroaryl or —ORa. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds and to intermediates for preparation of said compounds.

Abstract: Transfer films, articles made therewith, and methods of making and using transfer films to form an electrical stack are disclosed. The transfer films (100) may include a plurality of co-extensive electrical protolayers (22, 23, 24) forming an electrical protolayer stack (20), at least selected or each electrical protolayer independently comprising at least 25 wt % sacrificial material and a thermally stable material and having a uniform thickness of less than 25 micrometers. The transfer films may include a plurality of co-extensive electrical protolayers forming an electrical protolayer stack, at least selected or each protolayer independently exhibiting a complex viscosity of between 103 and 104 Poise at a shear rate of 100/s when heated to a temperature between its Tg and Tdec.

Abstract: Multilayered polymer films are configured so that successive constituent layer packets can be delaminated in continuous sheet form from the remaining film. The new films are compatible with known coextrusion manufacturing techniques, and can also be made without the use of adhesive layers between layer packets that are tailored to be individually peelable from the remainder of the film. Instead, combinations of polymer compositions are used to allow non-adhesive polymer layers to be combined in such a way that delamination of the film is likely to occur along a plurality of delamination surfaces corresponding to interfaces between particular pairs of layers for which the peel strength is reduced relative to the peel strength at other layer interfaces within the film. The absence of an adhesive between peelable layer packets results in the delamination being irreversible.

Abstract: Multilayered polymer films are configured so that successive constituent layer packets can be delaminated in continuous sheet form from the remaining film. The films are compatible with known coextrusion manufacturing techniques, and can be made without adhesive layers between layer packets that are tailored to be individually peelable from the film. Instead, combinations of polymer compositions are used to allow non-adhesive polymer layers to be combined such that irreversible delamination of the film is likely to occur at interfaces between layer packet pairs. Some polymer layers, including at least one embedded layer, may include an ultraviolet (UV) light stabilizer such as a UV absorber, antioxidant, or hindered amine light stabilizer (HALS), and these layers may be positioned at the front of each layer packet. After the UV-stabilized layer of one packet has been used, the packet can be peeled away to expose a new UV-stabilized layer of the next layer packet.

Abstract: Methods and apparatus for smoothly and efficiently upgrading set top boxes, e.g., personal video recorders, which have customer selected content stored thereon are described. The described methods allow content stored on a set top box to be uploaded to a network storage device, e.g., automatically at a predetermined time prior to a scheduled upgrade, or in some cases, via manual control of the set top box to be upgraded. After stored content is uploaded to the network storage device, the set top box is replaced with a new set top box. The new set top box can be preloaded with the previously uploaded content or a content download can be triggered, e.g., by activating a hidden application and by supplying information identifying the set top box being replaced as part of the upgrade process.

Abstract: A multilayer optical film has a packet of microlayers that selectively reflect light by constructive or destructive interference to provide a first reflective characteristic. At least some of the microlayers are birefringent. A stabilizing layer attaches to and covers the microlayer packet proximate an outer exposed surface of the film. Heating element(s) can physically contact the film to deliver heat to the packet through the stabilizing layer by thermal conduction, at altered region(s) of the film, such that the first reflective characteristic changes to an altered reflective characteristic in the altered region(s) to pattern the film. The stabilizing layer provides sufficient heat conduction to allow heat from the heating elements to change (e.g.

Abstract: A self-adhering tape is described comprising a substrate layer having a first major surface and opposing major surface; an adhesive layer disposed on the first major surface of the polyolefin substrate, the adhesive layer comprising a polyolefin polymer and optionally further comprising a tackifying resin; an outer layer disposed on the opposing major surface of the polyolefin substrate, the outer layer comprising a polymer comprising at least 50 wt-% C2-C3 alkylene and at least 20 wt-% C4-C20 ?-olefin. The self-adhering tape is suitable for use as a grip tape or an electrical tape. Methods of making and using the tape are also described.

Abstract: An intelligent receptacle (or receptacle device) enables individually monitoring and/or controlling consumption of utility service by one or more loads through a supply outlet that is associated with the receptacle device. A client device may enable a user to remotely control a provision of the utility service from the supply outlet through the receptacle device. Furthermore, a utility metering device may include a virtual metering device instance that is configured to collect utility consumption data associated with the supply outlet from the receptacle device and help calibration or synchronization of utility consumption readings of the receptacle device.

Abstract: Devices and systems for use in soft tissue repair are provided, as are methods of manufacturing the same. In one exemplary embodiment, an implantable surgical construct includes an implant and a continuous braided closed filament loop that is attached to the implant. The continuous loop can be formed from a single strand of filament such that portions of the filament, sometimes referred to as tails, can be arranged with respect to each other to form a braided configuration. A related method of manufacture can involve passing portions of a single strand of filament around different sets of posts and selectively over and under each other to create the braided configuration. Other devices, systems, and methods of manufacturing are also provided, including some that involve using multiple strands of suture to form a continuous braided closed filament loop.

Abstract: A fingerprint imaging system is described comprising a film including an optically transparent self-wetting adhesive layer adhered to an imaging surface of an electronic optical image sensor. Also described is a method of use of an optical imaging system, and a film and multilayer film suitable for use with a fingerprint imaging system.

Abstract: Substrates suitable for use in a touch sensor are described. In some cases, the substrates include an inner layer and first and second heat-set polymeric outer layers. The first and second outer layers each have an in-plane birefringence of less than 0.1. The inner layer is substantially uniaxially birefringent and has an in-plane birefringence greater than 0.01. In some cases, a substrate includes a block copolymer which includes a first polyester and second polyester. The first polyester has a melting point greater than 200 ° C., and the second polyester having a melting point less than 200° C. The block copolymer includes the second polyester at 50 to 80 percent by weight. The substrate is substantially uniaxially birefringent and has an in-plane birefringence between 0.001 and 0.1.

Abstract: A multilayer optical film has a packet of microlayers that selectively reflect light by constructive or destructive interference to provide a first reflective characteristic. At least some of the microlayers are birefringent. A stabilizing layer attaches to and covers the microlayer packet proximate an outer exposed surface of the film. Heating element(s) can physically contact the film to deliver heat to the packet through the stabilizing layer by thermal conduction, at altered region(s) of the film, such that the first reflective characteristic changes to an altered reflective characteristic in the altered region(s) to pattern the film. The stabilizing layer provides sufficient heat conduction to allow heat from the heating elements to change (e.g.

Abstract: A method of operating an interconnect server for a roaming network, the roaming network having a plurality of cellular networks and a plurality of hotspot networks formed of wireless access points, the interconnect server being connectable to a routing server within each of the plurality of cellular networks and to a routing server within each of the plurality of hotspot networks, wherein the plurality of hotspot networks are operable to allow subscriber devices of the plurality of cellular networks to connect to a wireless access point forming part of the hotspot network and access the device's subscriber cellular network, is disclosed.

Abstract: A method and arrangement for the coordinated, distributed, and linearly ordered collection and publication of event streams (i.e. time series data) includes features that harden it against internal errors, network partitions, data loss/corruption, and adversaries who wish to tamper with or interrupt its operation. Two modes of operation are described, one in which events are processed in aggregate (batching), and another in which updates occur continuously across the system.

Abstract: A method of operating a linear friction welding system in one embodiment includes positioning a phase change assembly driven by a motor in different configurations to establish different phase relationships between two eccentrically engaged power shafts while one of the power shafts is driven by the motor and the other power shaft is driven by the phase change assembly. In one phase change assembly configuration a ram operably connected to one of two components to be welded does not vibrate when the first power shaft and the second power shaft rotate while in another phase change assembly configuration the ram vibrates. Pressure between the two components is controlled to provide scrub pressure when the ram vibrates and forge pressure when the ram is no longer vibrating.

Abstract: A first server comprises at least one processor configured to establish a connection between a terminal and a second server in a communications network. A connection is established between the terminal and the server by associating credentials with a user of the terminal; receiving from the second server over a non-WebRTC communications channel, a connection request comprising the CLI or the URI; identifying from the CLI or the URI comprised in the connection request, an address for the terminal; setting up the connection between the second server and the terminal; in which the connection comprises a WebRTC channel extending to the terminal and a non-WebRTC channel extending to the second server; in which the WebRTC channel and the non-WebRTC channel are interconnected for communication at an intermediate point of the connection; and disassociating the credentials from the user at a time at which it is determined that the user no longer requires the credentials.

Abstract: Processing tapes for use in preparing optical articles include a thermally stable tape backing and a low tack adhesive layer at least partially coated on tape backing. The low tack adhesive layer includes a crosslinked, polyester-containing (meth)acrylate-based polymer that is essentially free of volatile components, is unchanged after heat aging of 150 C for 1 hour under a pressure of 4.31 kiloPascals, and is able to removably adhere to the anti-reflective, nanostructured surface coating of an optical construction.

Abstract: Barrier assemblies including ultrathin barrier laminates and methods of making the barrier assemblies are provided. A barrier assembly includes a thermoplastic polymer skin layer having opposite first and second major surfaces, and a barrier stack coated on the first major surface of the thermoplastic polymer skin layer to form an integral protective layer having a thickness no greater than about 0.5 mil (about 12.7 microns). The removable carrier film has a major surface releasably attached to the second major surface of the thermoplastic polymer skin layer. In some cases, the removal of the carrier film results in ultrathin barrier laminates.

Abstract: A double suction impeller features an impeller main body and an impeller suction eye. The impeller main body may include a suction eye adapter coupling member. The impeller suction eye may include a removable suction eye adapter having a corresponding suction eye adapter coupling member configured to couple detachably to the suction eye adapter coupling member of the impeller main body, whereby the removable suction eye adapter can be removed and replaced when wear and erosion occurs and can be a separate cast and/or machined piece.

Abstract: A multilayer optical film has a packet of microlayers that selectively reflect light by constructive or destructive interference to provide a first reflective characteristic. At least some of the microlayers are birefringent. A stabilizing layer attaches to and covers the microlayer packet proximate an outer exposed surface of the film. Heating element(s) can physically contact the film to deliver heat to the packet through the stabilizing layer by thermal conduction, at altered region(s) of the film, such that the first reflective characteristic changes to an altered reflective characteristic in the altered region(s) to pattern the film. The stabilizing layer provides sufficient heat conduction to allow heat from the heating elements to change (e.g.