Patents by Inventor Stephen Jolles

Stephen Jolles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL USES
    Publication number: 20210236513
    Abstract: This invention relates to the compound clozapine and its major metabolite norclozapine and prodrugs thereof and pharmaceutically acceptable salts and solvates thereof for use in the treatment or prevention of a pathogenic immunoglobulin driven B cell disease. The invention also provides pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: January 31, 2019
    Publication date: August 5, 2021
    Applicant: ZARODEX THERAPEUTICS LIMITED
    Inventors: Stephen JOLLES, Houman ASHRAFIAN, Duncan MCHALE
  • CLOZAPINE FOR THE TREATMENT OF A IMMUNOGLOBULIN DRIVEN B CELL DISEASE
    Publication number: 20210236512
    Abstract: This invention relates to the compound clozapine and its major metabolite norclozapine and prodrugs thereof and pharmaceutically acceptable salts and solvates thereof for use in the treatment or prevention of a pathogenic immunoglobulin driven B cell disease with a T cell component. The invention also provides pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: January 31, 2019
    Publication date: August 5, 2021
    Applicant: ZARODEX THERAPEUTICS LIMITED
    Inventors: Stephen JOLLES, Houman ASHRAFIAN, Duncan MCHALE
  • CLOZAPINE FOR THE TREATMENT OF IG-E DRIVEN B CELL DISEASES
    Publication number: 20210137941
    Abstract: This invention relates to the compound clozapine and its major metabolite norclozapine and prodrugs thereof and pharmaceutically acceptable salts and solvates thereof for use in the treatment or prevention of a pathogenic IgE driven B cell disease. The invention also provides pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: January 31, 2019
    Publication date: May 13, 2021
    Applicant: ZARODEX THERAPEUTICS LIMITED
    Inventors: Stephen JOLLES, Houman ASHRAFIAN, Duncan MCHALE
  • Method for the treatment or prophylaxis of tuberculosis
    Patent number: 7687060
    Abstract: The invention provides the use of intravenous immunoglobulin (IVIg) in the preparation of a medicament for the treatment and/or prophylaxis of mycobacterial infection.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: March 30, 2010
    Assignee: Medical Research Council
    Inventors: Stephen Jolles, Ricardo Tascon, Douglas Lowrie, Vangelis Stavropoulos
  • Method for the treatment or prophylaxis of tuberculosis
    Publication number: 20060275311
    Abstract: The invention provides the use of intravenous immunoglobulin (IVIg) in the preparation of a medicament for the treatment and/or prophylaxis of mycobacterial infection.
    Type: Application
    Filed: March 8, 2006
    Publication date: December 7, 2006
    Inventors: Stephen Jolles, Ricardo Tascon, Douglas Lowrie, Vangelis Stavropoulos