Abstract: Provided are methods for selecting parameters of an electrical pulse for electroporation to induce apoptosis in a tissue in need of therapeutic removal in a patient. Also provided are methods and apparatuses for treating a disease by inducing apoptosis in a tissue in need of therapeutic removal in a patient. Further provided are computer-readable media having instructions for selecting parameters of an electrical pulse for electroporation to induce apoptosis in a tissue in need of therapeutic removal in a patient.

Abstract: An attachment for a weight stack type exercise machine to pull the weight stack down while it is being lowered, (or to pull on a weight stack lifting means so as to add to the force applied to the lifting means by the weight stack) so that the eccentric exercise force required to lower the stack is greater than the concentric exercise force required to raise it. Such asymmetric exercise forces more closely match muscle strengths, which are normally greater for eccentric exercise than for concentric exercise. The attachment has an electric motor and a control unit including a keypad, a display and a microcontroller. The motor is coupled to the weight stack by an eccentric force control cable or a toothed belt or alternatively is operatively connected so as to apply additional force to the lifting arrangement. The keypad allows the user to select the amount of force added during the eccentric phase of exercise, when the weight stack is moving down.

Abstract: An attachment for a weight stack type exercise machine to pull the weight stack down while it is being lowered, so that the eccentric exercise force required to lower the stack is greater than the concentric exercise force required to raise it. Such asymmetric exercise forces more closely match muscle strengths, which are normally greater for eccentric exercise than for concentric exercise. The attachment has an electric motor and a control unit including a keypad, a display and a microcontroller. The motor is coupled to the weight stack by an eccentric force control cable. The keypad allows the user to select the amount of force added during the eccentric phase of exercise, when the weight stack is moving down and part of a lifting cable connected to a handle or engageable member on the weight stack type machine is moving in. A sensor enables the controller to determine whether the weight stack is moving up or down.

Abstract: A motor-driven treadmill includes a stationary ultrasonic range finder which continuously measures the distance to the torso of a person walking or running on the moving tread of the treadmill. When the person approaches too closely to the front of the treadmill, the treadmill speed and/or the treadmill slope are increased; and when the person retreats too far away from the front of the treadmill, the treadmill speed and/or the treadmill slope are decreased. The response of the treadmill speed and/or slope control system may be improved by making the controller responsive to the rate of change of the distance between the person using the treadmill and the front of the treadmill, so as to provide anticipation of the distances which will be traversed by the user of the treadmill.

Abstract: A probe adapted for insertion in living tissue for measuring oxygen partial pressure and temperature at a plurality of sites in living tissue is provided. A temperature sensitive resistor is positioned adjacent each of a plurality of oxygen sensors so that the oxygen partial pressure measured can be adjusted for tissue temperature. The probe substrate has thermal properties similar to living tissue and the resistors are formed of a material having a temperature sensitive resistance. Temperature at each temperature sensitive resistor is obtained by measuring resistance with a four point measurement and correlating the resistance to temperature.

Abstract: Malfunctions of the cardiovascular control system may be diagnosed by examination of a patient's heart rate fluctuation power spectra. Particularly indicative of cardiovascular stress are: a level below about 0.1 (beats/min.).sup.2 in the power spectrum of heart rate fluctuations at a frequency between about 0.04 and about 0.10 Hz; a marked increase to above about 10 (beats/min.).sup.2 in a peak in the heart rate fluctuation power spectrum between about 0.04 to 0.10 Hz; and a ratio of the area under a heart rate power spectrum peak at a frequency between about 0.04 and 0.10 Hz to the area under a peak in the respiratory heart rate fluctuation power spectrum centered at the mean respiratory rate about about 0.10 Hz as having an absolute value less than 2.0 for longer than or equal to about one hour or as having an absolute value greater than about 50.

Abstract: Oxygen partial pressure and temperature are measured in living tissue by inserting a thin probe into living tissue. The probe includes a plurality of spatially separated thermal sensors secured to the probe substrate. A plurality of oxygen sensors is positioned along the length of the probe substrate and each oxygen sensor is associated with and positioned adjacent to or is an integral part of one of the thermal sensors. Electrical parameters of the sensors located on the probe are measured and used to determine oxygen partial pressure and to determine temperature at each of a plurality of sites along the probe.