Patents by Inventor Stephen K. Picataggio

Stephen K. Picataggio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040077068
    Abstract: A method for the production of carotenoid compounds is disclosed. The method relies on the use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds in high yields.
    Type: Application
    Filed: September 4, 2003
    Publication date: April 22, 2004
    Inventors: Patricia C. Brzostowicz, Qiong Cheng, Deana J. Dicosimo, Mattheos Koffas, Edward S. Miller, James Martin Odom, Stephen K. Picataggio, Pierre E. Rouviere
  • Publication number: 20040063143
    Abstract: Genes have been isolated from Methylomonas 16a sp. encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Methylomonas strain that is capable of utilizing single carbon (C1) substrates as energy sources. The genes and gene products of the present invention may be used in a variety of ways for the production of isoprenoid compounds in a variety of organisms.
    Type: Application
    Filed: November 3, 2003
    Publication date: April 1, 2004
    Inventors: Qiong Cheng, Mattheos Koffas, Kelley C. Norton, James M. Odom, Stephen K. Picataggio, Andreas Schenzle, Jean-Francois Tomb, Pierre E. Rouviere
  • Patent number: 6660507
    Abstract: Genes have been isolated from Methylomonas 16a sp. encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Methylomonas strain that is capable of utilizing single carbon (C1) substrates as energy sources. The genes and gene products of the present invention may be used in a variety of ways for the production of isoprenoid compounds in a variety of organisms.
    Type: Grant
    Filed: August 22, 2001
    Date of Patent: December 9, 2003
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Qiong Cheng, Mattheos Koffas, Kelley C. Norton, James M. Odom, Stephen K. Picataggio, Andreas Schenzle, Jean-Francois Tomb, Pierre E. Rouviere
  • Publication number: 20030148319
    Abstract: Genes have been isolated from Pantoea stewartii encoding geranylgeranyl pyrophosphate (GGPP) synthase (crtE), phytoene synthase (crtB), phytoene desaturase(crtI), lycopene cyclase(crtY), &bgr;-carotene hydroxylase(crtZ), and zeaxanthin glucosyl transferase (crtX) activity. The genes and their products are useful for the conversion of phytoene to the carotenoids. Vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes and &bgr;-carotene by recombinant DNA technology in transformed host organisms are disclosed.
    Type: Application
    Filed: August 13, 2002
    Publication date: August 7, 2003
    Inventors: Patricia C. Brzostowicz, Qiong Cheng, Stephen K. Picataggio, Pierre E. Rouviere
  • Publication number: 20030003528
    Abstract: A method for the production of carotenoid compounds is disclosed. The method relies on the use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds in high yields.
    Type: Application
    Filed: August 29, 2001
    Publication date: January 2, 2003
    Inventors: Patricia C. Brzostowicz, Qiong Cheng, Deana Dicosimo, Mattheos Koffas, Edward S. Miller, James M. Odom, Stephen K. Picataggio, Pierre E. Rouviere
  • Publication number: 20020102690
    Abstract: Genes have been isolated from Methylomonas 16a sp. encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Methylomonas strain that is capable of utilizing single carbon (C1) substrates as energy sources. The genes and gene products of the present invention may be used in a variety of ways for the production of isoprenoid compounds in a variety of organisms.
    Type: Application
    Filed: August 22, 2001
    Publication date: August 1, 2002
    Inventors: Qiong Cheng, Mattheos Koffas, Kelley C. Norton, James M. Odom, Stephen K. Picataggio, Andreas Schenzle, Jean-Francois Tomb, Pierre E. Rouviere
  • Patent number: 6013494
    Abstract: Recombinant organisms are provided comprising genes encoding glycerol-3-phosphate dehydrogenase, glycerol-3-phosphatase, glycerol dehydratase and 1,3-propanediol oxidoreductase activites useful for the production of 1,3-propanediol from a variety of carbon substrates.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: January 11, 2000
    Assignees: E. I. du Pont de Nemours and Company, Genencor International
    Inventors: Charles E. Nakamura, Anthony A. Gatenby, Amy Kuang-Hua Hsu, Richard D. La Reau, Sharon L. Haynie, Maria Diaz-Torres, Donald E. Trimbur, Gregory M. Whited, Vasantha Nagarajan, Mark S. Payne, Stephen K. Picataggio, Ramesh V. Nair
  • Patent number: 5843760
    Abstract: This invention relates to single microorganisms which normally do not ferment pentose sugars which are genetically altered to ferment the pentose sugars, xylose and arabinose, to produce ethanol, and a fermentation process utilizing the same. Examples include Zymomonas mobilis which has been transformed with a combination of E. coli genes for xylose isomerase, xylulokinase, L-arabinose isomerase, L-ribulokinase, L-ribulose 5-phosphate 4-epimerase, transaldolase and transketolase. Expression of added genes are under the control of Z. mobilis promoters. These newly created microorganisms are useful for fermenting glucose, xylose and arabinose, produced by hydrolysis of hemicellulose and cellulose or starch, to produce ethanol.
    Type: Grant
    Filed: May 6, 1997
    Date of Patent: December 1, 1998
    Assignee: Midwest Research Institute
    Inventors: Min Zhang, Yat-Chen Chou, Stephen K. Picataggio, Mark Finkelstein
  • Patent number: 5798237
    Abstract: A recombinant Lactobacillus MONT4 is provided which has been genetically engineered with xylose isomerase and xylulokinase genes from Lactobacillus pentosus to impart to the Lactobacillus MONT4 the ability to ferment lignocellulosic biomass containing xylose to lactic acid.
    Type: Grant
    Filed: October 10, 1995
    Date of Patent: August 25, 1998
    Assignee: Midwest Research Institute
    Inventors: Stephen K. Picataggio, Min Zhang, Mary Ann Franden, James D. Mc Millan, Mark Finkelstein
  • Patent number: 5726053
    Abstract: The invention relates to microorganisms which normally do not ferment pentose sugar and which are genetically altered to ferment pentose sugar to produce ethanol, and fermentation processes utilizing the same. Examples include Zymomonas mobilis which has been transformed with combinations of E. coli genes for xylose isomerase, xylulokinase, transaldolase, transketolase, L-arabinose isomerase, L-ribulokinase, and L-ribulose-5-phosphate 4-epimerase. Expression of the added genes are under the control of Zymomonas mobilis promoters. These newly created microorganisms are useful for fermenting pentoses and glucose, produced by hydrolysis of hemicellulose and cellulose, to produce ethanol.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: March 10, 1998
    Assignee: Midwest Research Institute
    Inventors: Stephen K. Picataggio, Min Zhang, Christina K. Eddy, Kristine A. Deanda
  • Patent number: 5712133
    Abstract: The invention relates to microorganisms which normally do not ferment pentose sugar and which are genetically altered to ferment pentose sugar to produce ethanol, and fermentation processes utilizing the same. Examples include Zymomonas mobilis which has been transformed with combinations of E. coli genes for xylose isomerase, xylulokinase, transaldolase, transketolase, L-arabinose isomerase, L-ribulokinase, and L-ribulose 5-phosphate 4-epimerase. Expression of the added genes are under the control of Zymomonas mobilis promoters. These newly created microorganisms are useful for fermenting pentoses and glucose, produced by hydrolysis of hemicellulose and cellulose, to produce ethanol.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: January 27, 1998
    Assignee: Midwest Research Institute
    Inventors: Stephen K. Picataggio, Min Zhang, Christina K. Eddy, Kristine A. Deanda, Mark Finkelstein, Ali Mohagheghi, Mildred M. Newman, James D. McMillan
  • Patent number: 5514583
    Abstract: The invention relates to microorganisms which normally do not ferment a pentose sugar and which are genetically altered to ferment this pentose to produce ethanol. A representative example is Zymomonas mobilis which has been transformed with E. coli xylose isomerase, xylulokinase, transaldolase and transketolase genes. Expression of the added genes are under the control of Zymomonas mobilis promoters. This newly created microorganism is useful for fermenting pentoses and glucose, produced by hydrolysis of hemicellulose and cellulose, to produce ethanol.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: May 7, 1996
    Assignee: Midwest Research Institute
    Inventors: Stephen K. Picataggio, Min Zhang, Christina K. Eddy, Kristine A. Deanda, Mark Finkelstein