Abstract: Compounds inhibitory to Staphylococcus pseudintermedius Sortase A (SrtA) are identified. The compounds inhibit cell wall-associated protein anchoring to the bacterial cell wall, thus potentially reducing bacterial virulence.

Abstract: Methods for detection of a tapeworm in an animal are provided, comprising contacting a biological sample from the animal with at least one antibody capable of binding to an antigen derived from Anoplocephala perfoliata, allowing an antigen-antibody complex to form, separating the biological sample and the antigen-antibody complex, and detecting the antigen-antibody complex. The antigen may be derived by incubating an A. perfoliata organism in a buffer solution, followed by isolating a preparation containing molecules having a molecular weight of at least about 100 kD from the incubated solution and separating at least one antigen having a molecular weight of from about 12 to about 13 kD from the preparation. Compositions for accomplishing the methods, and kits comprising the compositions are provided.