Patents by Inventor Stephen Keen

Stephen Keen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10435410
    Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: October 8, 2019
    Assignee: MERCK SHARP & DOHME CORPORATION
    Inventors: John Y. L. Chung, Kevin Campos, Edward Cleator, Robert F. Dunn, Andrew Gibson, R. Scott Hoerrner, Stephen Keen, Dave Lieberman, Zhuqing Liu, Joseph Lynch, Kevin M. Maloney, Feng Xu, Nobuyoshi Yasuda, Naoki Yoshikawa, Yong-Li Zhong
  • Publication number: 20190290418
    Abstract: The invention relates generally to methods and systems for irrigating or capturing particulates during heart pump implantation, and more specifically relates to irrigating, capturing, and removing particulates that may be released when coring a patient's heart tissue. In one aspect, a method for capturing particulates during heart pump implantation is provided that includes inserting a removable particulate capture device into a patient's heart prior to a coring procedure upon the patient's heart. The removable particulate capture device includes an expandable basket movable between collapsed and expanded configurations. The method further includes expanding the expandable basket to the expanded configuration from the collapsed configuration when the removable particulate capture device is positioned within the patient's heart to capture the particulates released during the coring procedure.
    Type: Application
    Filed: March 25, 2019
    Publication date: September 26, 2019
    Applicant: TC1 LLC
    Inventors: Stephen Franklin, Rachel Keen
  • Publication number: 20190016729
    Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
    Type: Application
    Filed: September 17, 2018
    Publication date: January 17, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: John Y.L. Chung, Kevin Campos, Edwards Cleator, Robert F. Dunn, Andrew Gibson, R. Scott Hoerrner, Stephen Keen, Dave Lieberman, Zhuqing Liu, Joseph Lynch, Kevin M. Maloney, Feng Xu, Nobuyoshi Yasuda, Naoki Yoshikawa, Yong-Li Zhong
  • Patent number: 10113343
    Abstract: Provided herein is a high intensity discharge light source having a thermally insulative and optically transparent sleeve for maintaining or enhancing a spectral performance parameter. The configuration of the sleeve provides an insulative volume that allows an elevated steady state operating temperature to be reached, even when the light source is cooled. The sleeve is also configured to withstand a bulb failure event, thereby protecting the surrounding environment from falling debris. Also provided herein are methods for dissipating heat from the light source without adversely affecting the bulb operating temperature or the enhanced spectral performance parameter.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: October 30, 2018
    Assignee: Surna Inc.
    Inventors: Stephen Keen, Todd Whitaker, Jordan Johnson, Chris Pearson, Brady Schultz
  • Patent number: 10087189
    Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: October 2, 2018
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: John Y. L. Chung, Kevin Campos, Edward Cleator, Robert F. Dunn, Andrew Gibson, R. Scott Hoerrner, Stephen Keen, Dave Lieberman, Zhuqing Liu, Joseph Lynch, Kevin M. Maloney, Feng Xu, Nobuyoshi Yasuda, Naoki Yoshikawa, Yong-Li Zhong
  • Publication number: 20180065973
    Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
    Type: Application
    Filed: November 9, 2017
    Publication date: March 8, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: John Y.L. CHUNG, Kevin CAMPOS, Edward CLEATOR, Robert F. DUNN, Andrew GIBSON, R. Scott HOERRNER, Stephen KEEN, Dave LIEBERMAN, Zhuqing LIU, Joseph LYNCH, Kevin M. MALONEY, Feng XU, Nobuyoshi YASUDA, Naoki YOSHIKAWA, Yong-Li ZHONG
  • Publication number: 20180029981
    Abstract: The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions:
    Type: Application
    Filed: September 26, 2017
    Publication date: February 1, 2018
    Inventors: John Y.L. CHUNG, Kevin CAMPOS, Edward CLEATOR, Robert F. DUNN, Andrew GIBSON, R. Scott HOERRNER, Stephen KEEN, Dave LIEBERMAN, Zhuqing LIU, Joseph LYNCH, Kevin M. MALONEY, Feng XU, Nobuyoshi YASUDA, Naoki YOSHIKAWA, Yong-Li ZHONG
  • Publication number: 20170370570
    Abstract: Provided herein is a high intensity discharge light source having a thermally insulative and optically transparent sleeve for maintaining or enhancing a spectral performance parameter. The configuration of the sleeve provides an insulative volume that allows an elevated steady state operating temperature to be reached, even when the light source is cooled. The sleeve is also configured to withstand a bulb failure event, thereby protecting the surrounding environment from falling debris. Also provided herein are methods for dissipating heat from the light source without adversely affecting the bulb operating temperature or the enhanced spectral performance parameter.
    Type: Application
    Filed: October 23, 2015
    Publication date: December 28, 2017
    Inventors: Stephen KEEN, Todd WHITAKER, Jordan JOHNSON, Chris PEARSON, Brady SCHULTZ
  • Patent number: 9822121
    Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: November 21, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: John Y. L. Chung, Kevin Campos, Edward Cleator, Robert F. Dunn, Andrew Gibson, R. Scott Hoerrner, Stephen Keen, Dave Lieberman, Zhuqing Liu, Joseph Lynch, Kevin M. Maloney, Feng Xu, Nobuyoshi Yasuda, Naoki Yoshikawa, Yong-Li Zhong
  • Patent number: 9809536
    Abstract: The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: November 7, 2017
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: John Y. L. Chung, Kevin Campos, Edward Cleator, Robert F. Dunn, Andrew Gibson, R Scott Hoerrner, Stephen Keen, Dave Lieberman, Zhuqing Liu, Joseph Lynch, Kevin M. Maloney, Feng Xu, Nobuyoshi Yasuda, Naoki Yoshikawa, Yong-Li Zhong
  • Publication number: 20170142910
    Abstract: Provided herein are optical reflectors having a plurality of specially designed reflective surfaces and geometrical arrangement to provide improved illumination of a target area. Also provided are related methods for growing plants with the optical reflectors described herein. The reflective surfaces provide substantially normally aligned light over the entire target area, thereby minimizing shading issues of conventional optical reflectors. Also disclosed herein are efficient cooling by air and/or fluid that can substantially reduce cooling requirements by conventional air conditioning with attendant power savings.
    Type: Application
    Filed: May 1, 2015
    Publication date: May 25, 2017
    Applicant: Surna Inc.
    Inventors: Jordan JOHNSON, Stephen KEEN, Chris PEARSON, Todd WHITAKER
  • Patent number: 9620925
    Abstract: An optical combiner (25), comprising a bundle of input fibers (24) spliced to an output fiber (26), the output fiber having a cladding and at least one high-index portion within the cladding, such that the high index portion has a diameter substantially equal to or less than the outer diameter of the input fiber bundle at the splice point.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: April 11, 2017
    Assignee: SPI Lasers UK Limited
    Inventors: Stephen Keen, Stephen Moore, Iain Botheroyd
  • Publication number: 20160176884
    Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
    Type: Application
    Filed: March 1, 2016
    Publication date: June 23, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: John Y.L. Chung, Kevin Campos, Edward Cleator, Robert F. Dunn, Andrew Gibson, R. Scott Hoerrner, Stephen Keen, Dave Lieberman, Zhuqing Liu, Joseph Lynch, Kevin M. Maloney, Feng Xu, Nobuyoshi Yasuda, Naoki Yoshikawa, Yong-Li Zhong
  • Patent number: 9233434
    Abstract: A method of optimizing the focus of a fibers laser is described, which comprises positioning the output of a fibers laser relative to a workpiece; measuring at least a portion of back reflected radiation from the workpiece (step 52); determining an integral of this; changing the relative position of the output and the workpiece one or more times (step 54,56), each time determining an integral of values for the back-reflection, and using the integrals to determine optimum focus.
    Type: Grant
    Filed: July 19, 2011
    Date of Patent: January 12, 2016
    Assignee: SPI LASERS UK LIMITED
    Inventor: Stephen Keen
  • Publication number: 20150372444
    Abstract: An optical combiner (25), comprising a bundle of input fibres (24) spliced to an output fibre (26), the output fibre having a cladding and at least one high-index portion within the cladding, such that the high index portion has a diameter substantially equal to or less than the outer diameter of the input fibre bundle at the splice point.
    Type: Application
    Filed: January 27, 2014
    Publication date: December 24, 2015
    Inventors: Stephen Keen, Stephen Moore, Iain Botheroyd
  • Patent number: D748319
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: January 26, 2016
    Assignee: Surna Inc.
    Inventors: Jordan Johnson, Stephen Keen, Thomas Bollich, Chris Pearson, Todd Whitaker
  • Patent number: D748320
    Type: Grant
    Filed: November 11, 2014
    Date of Patent: January 26, 2016
    Assignee: Surna Inc.
    Inventors: Jordan Johnson, Stephen Keen, Thomas Bollich, Chris Pearson, Todd Whitaker
  • Patent number: D748847
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: February 2, 2016
    Assignee: Surna Inc.
    Inventors: Jordan Johnson, Stephen Keen, Thomas Bollich, Chris Pearson, Todd Whitaker
  • Patent number: D748850
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: February 2, 2016
    Assignee: Surna Inc.
    Inventors: Jordan Johnson, Stephen Keen, Thomas Bollich, Chris Pearson, Todd Whitaker
  • Patent number: D794842
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: August 15, 2017
    Assignee: Surna Inc.
    Inventors: Stephen Keen, Chris Pearson, Brady Schultz, Jordan Johnson