Patents by Inventor Stephen L. Bolea

Stephen L. Bolea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200316373
    Abstract: A method including chronically implanting a nerve cuff electrode on a portion of a hypoglossal nerve, chronically implanting a respiration sensing lead subcutaneously in a thorax of a patient, the respiration sensing lead having a plurality of bio-impedance electrodes defining at least one bio-impedance vector. The method may also include sensing a bio-impedance signal corresponding to respiration via a bio-impedance vector on an anterior side of the thorax, analyzing the bio-impedance signal to identify onsets of expiration, predicting an onset of a future expiratory phase, and delivering a stimulus to the portion of the hypoglossal nerve via the nerve cuff electrode, wherein the stimulus is delivered as a function of the bio-impedance signal; wherein stimulus delivery is initiated before the onset of the future expiratory phase and continued during an entire inspiratory phase, and wherein the method is performed without identifying an onset of an inspiratory phase.
    Type: Application
    Filed: April 16, 2020
    Publication date: October 8, 2020
    Applicant: LivaNova USA, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Bruce J. Persson, Robert E. Atkinson, Scott T. Mazar
  • Publication number: 20200254245
    Abstract: An implantable neurostimulation system comprises a stimulation delivery lead and a neurostimulator. The stimulation delivery lead is coupled to an electrode. The neurostimulator is adapted to deliver a neurostimulation signal to the subject and comprises a microprocessor. The microprocessor is programmed to identify a stimulation operating window for the therapy including a first threshold and a second threshold. The second threshold comprises an awake level and an asleep level. Identifying the stimulation operating window comprises titrating a stimulation setting of the neurostimulator while the subject is awake until the first threshold and the awake level of the second threshold are identified. Identifying the stimulation operating window further comprises subsequently repeating the step of titrating the stimulation setting of the neurostimulator while the subject is asleep until the asleep level of the second threshold is identified.
    Type: Application
    Filed: April 24, 2020
    Publication date: August 13, 2020
    Applicant: LivaNova USA, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney Hauschild, Paula M. Kaplan, Adam K. Hoyhtya, Wondimeneh Tesfayesus, Robert E. Atkinson, Peter R. Eastwood, David R. Hillman
  • Patent number: 10737094
    Abstract: Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: August 11, 2020
    Assignee: LivaNova USA, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney F. Hauschild, Paula M. Kaplan, Adam K. Hoyhtya, Wondimeneh Tesfayesus, Robert E. Atkinson
  • Patent number: 10632308
    Abstract: A method including chronically implanting a nerve cuff electrode on a portion of a hypoglossal nerve, chronically implanting a respiration sensing lead subcutaneously in a thorax of a patient, the respiration sensing lead having a plurality of bio-impedance electrodes defining at least one bio-impedance vector. The method may also include sensing a bio-impedance signal corresponding to respiration via a bio-impedance vector on an anterior side of the thorax, analyzing the bio-impedance signal to identify onsets of expiration, predicting an onset of a future expiratory phase, and delivering a stimulus to the portion of the hypoglossal nerve via the nerve cuff electrode, wherein the stimulus is delivered as a function of the bio-impedance signal; wherein stimulus delivery is initiated before the onset of the future expiratory phase and continued during an entire inspiratory phase, and wherein the method is performed without identifying an onset of an inspiratory phase.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: April 28, 2020
    Assignee: LivaNova USA, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Bruce J. Persson, Robert E. Atkinson, Scott T. Mazar
  • Patent number: 10632306
    Abstract: Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: April 28, 2020
    Assignee: LivaNova USA, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney Hauschild, Paula M. Kaplan, Adam K. Hoyhtya, Wondimeneh Tesfayesus, Robert E. Atkinson, Peter R. Eastwood, David R. Hillman
  • Publication number: 20200114153
    Abstract: Devices, systems, and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.
    Type: Application
    Filed: August 22, 2019
    Publication date: April 16, 2020
    Inventors: Stephen L. Bolea, Robert S. Kieval, Bruce J. Persson, David J. Serdar, Peter T. Keith, Eric D. Irwin, Martin A. Rossing
  • Publication number: 20190274587
    Abstract: Devices and methods for treating obstructive sleep apnea by first performing an assessment of the patient that involves observing the patient's upper airway during a tongue protrusion maneuver. The assessment may, for example, be done using endoscopy to observe the upper airway while the patient is awake in the supine position. An adequate response of the upper airway during the tongue protrusion maneuver is indicative of likely therapeutic success with hypoglossal nerve stimulation, and may be used for making clinical decisions. The principles of the present invention may be applied to other therapeutic interventions for OSA involving the upper airway.
    Type: Application
    Filed: March 15, 2019
    Publication date: September 12, 2019
    Applicant: LivaNova USA, Inc.
    Inventors: Wondimeneh TESFAYESUS, Stephen L. BOLEA, Peter R. EASTWOOD, David R. HILLMAN
  • Patent number: 10391308
    Abstract: A medical lead is provided for use in a pulse stimulation system of the type which includes a pulse generator for producing electrical stimulation therapy. The lead comprises an elongate insulating body and at least one electrical conductor within the insulating body. The conductor has a proximal end configured to be electrically coupled to the pulse generator and has a DC resistance in the range of 375-2000 ohms. At least one distal electrode is coupled to the conductor.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: August 27, 2019
    Assignee: Medtronic, inc.
    Inventors: Carl D. Wahlstrand, Robert M. Skime, Gregory A. Hrdlicka, James M. Olsen, Stephen L. Bolea
  • Publication number: 20190151656
    Abstract: Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
    Type: Application
    Filed: October 18, 2018
    Publication date: May 23, 2019
    Applicant: CYBERONICS, INC.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney F. Hauschild, Paula M. Kaplan, Adam K. Hoyhtya, Wondimeneh Tesfayesus, Robert E. Atkinson
  • Patent number: 10231645
    Abstract: Devices and methods for treating obstructive sleep apnea by first performing an assessment of the patient that involves observing the patient's upper airway during a tongue protrusion maneuver. The assessment may, for example, be done using endoscopy to observe the upper airway while the patient is awake in the supine position. An adequate response of the upper airway during the tongue protrusion maneuver is indicative of likely therapeutic success with hypoglossal nerve stimulation, and may be used for making clinical decisions. The principles of the present invention may be applied to other therapeutic interventions for OSA involving the upper airway.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: March 19, 2019
    Assignee: LivaNova USA, Inc.
    Inventors: Wondimeneh Tesfayesus, Stephen L. Bolea, Peter R. Eastwood, David R. Hillman
  • Publication number: 20190060633
    Abstract: An assembly for forming a medical lead includes a lead body, a plurality of electrical conductors extending about a longitudinal axis of the lead body, and at least one segmented electrode preform that includes an electrically conductive ring and an insulator portion within the electrically conductive ring. The electrically conductive ring includes a plurality of electrode portions and a plurality of raised portions that alternate continuously around the ring. Each of the plurality of electrode portions is continuous at a radius from a center of the electrically conductive ring that corresponds to an outer perimeter of the medical lead. The insulator portion has a plurality of projections each extending into a respective raised portion of the ring beyond a radius that corresponds to the outer perimeter of the medical lead. Each respective electrode portion is electrically coupled to a respective electrical conductor of the plurality of electrical conductors.
    Type: Application
    Filed: July 9, 2018
    Publication date: February 28, 2019
    Inventors: Sean P. Skubitz, Daniel C. Oster, Jacob Silverberg, Stephen L. Bolea, Jayesh R. Patel, Jeffrey M. Novotny, Justin M. Claus, Robert R. Rowe, Wayne M. Starkson
  • Publication number: 20190060639
    Abstract: An insulative body of a medical electrical lead electrode assembly includes a pre-formed channel having a section extending at an angle to a longitudinal axis of the body. An electrode portion of a conductive component has an electrode contact surface facing outward from a first side of the body and a coupling portion embedded in the body. A conductor, which is coupled to the coupling portion of the component, is disposed in the channel.
    Type: Application
    Filed: October 29, 2018
    Publication date: February 28, 2019
    Inventors: Sean P. Skubitz, Mary L. Boatwright, Stephen L. Bolea, Jessica L. Tower, Michael E. Metzler
  • Publication number: 20190060634
    Abstract: A medical lead system includes a lead body, a plurality of electrical conductors, and a plurality of electrodes. The lead body may include a distal end and a proximal end defining a longitudinal axis of the lead body. The plurality of electrical conductors extending about the longitudinal axis of the lead body. The plurality of electrodes is positioned around an outer perimeter of the lead body. An inner surface of each of the plurality of electrodes defines an inner perimeter. Each respective electrode of the plurality of electrodes is electrically coupled to a respective electrical conductor of the plurality of electrical conductors. Each electrode of the plurality of electrodes includes at least one electrode locking feature extending into the lead body from the inner perimeter.
    Type: Application
    Filed: July 19, 2018
    Publication date: February 28, 2019
    Inventors: Sean P. Skubitz, Daniel C. Oster, Jacob Silverberg, Stephen L. Bolea, Jayesh R. Patel
  • Patent number: 10112044
    Abstract: An insulative body of a medical electrical lead electrode assembly includes a pre-formed channel having a section extending at an angle to a longitudinal axis of the body. An electrode portion of a conductive component has an electrode contact surface facing outward from a first side of the body and a coupling portion embedded in the body. A conductor, which is coupled to the coupling portion of the component, is disposed in the channel.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: October 30, 2018
    Assignee: MEDTRONIC, INC.
    Inventors: Sean P. Skubitz, Mary L. Boatwright, Stephen L. Bolea, Jessica L. Tower, Michael E. Metzler
  • Patent number: 10105538
    Abstract: Devices, systems and methods of neurostimulation for treating obstructive sleep apnea.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: October 23, 2018
    Assignee: Cyberonics, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney F. Hauschild, Paula M. Kaplan, Adam K. Hoyhtya, Wondimeneh Tesfayesus, Robert E. Atkinson
  • Publication number: 20180200512
    Abstract: Devices, systems and methods of neurostimulation for treating obstructive sleep apnea. The system is adapted to send an electrical signal from an implanted neurostimulator through a stimulation lead to a patient's nerve at an appropriate phase of the respiratory cycle based on input from a respiration sensing lead. External components are adapted for wireless communication with the neurostimulator. The neurostimulator is adapted to deliver therapeutic stimulation based on inputs.
    Type: Application
    Filed: March 12, 2018
    Publication date: July 19, 2018
    Applicant: Cyberonics, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney F. Hauschild, Wondimeneh Tesfayesus, Jason J. Skubitz, Mark R. Bosshard, Daniel A. Parrish, Robert E. Atkinson
  • Publication number: 20180078761
    Abstract: A method including chronically implanting a nerve cuff electrode on a portion of a hypoglossal nerve, chronically implanting a respiration sensing lead subcutaneously in a thorax of a patient, the respiration sensing lead having a plurality of bio-impedance electrodes defining at least one bio-impedance vector. The method may also include sensing a bio-impedance signal corresponding to respiration via a bio-impedance vector on an anterior side of the thorax, analyzing the bio-impedance signal to identify onsets of expiration, predicting an onset of a future expiratory phase, and delivering a stimulus to the portion of the hypoglossal nerve via the nerve cuff electrode, wherein the stimulus is delivered as a function of the bio-impedance signal; wherein stimulus delivery is initiated before the onset of the future expiratory phase and continued during an entire inspiratory phase, and wherein the method is performed without identifying an onset of an inspiratory phase.
    Type: Application
    Filed: July 31, 2017
    Publication date: March 22, 2018
    Applicant: CYBERONICS, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Bruce J. Persson, Robert E. Atkinson, Scott T. Mazar
  • Patent number: 9913982
    Abstract: Devices, systems and methods of neurostimulation for treating obstructive sleep apnea. The system is adapted to send an electrical signal from an implanted neurostimulator through a stimulation lead to a patient's nerve at an appropriate phase of the respiratory cycle based on input from a respiration sensing lead. External components are adapted for wireless communication with the neurostimulator. The neurostimulator is adapted to deliver therapeutic stimulation based on inputs.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: March 13, 2018
    Assignee: Cyberonics, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Brian D. Kuhnley, Dale G. Suilmann, Bruce J. Persson, John P. Beck, Sidney F. Hauschild, Wondimeneh Tesfayesus, Jason J. Skubitz, Mark R. Bosshard, Daniel A. Parrish, Robert E. Atkinson
  • Patent number: RE48024
    Abstract: Devices, systems and methods for nerve stimulation for OSA therapy.
    Type: Grant
    Filed: April 8, 2015
    Date of Patent: June 2, 2020
    Assignee: LivaNova USA, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Bruce J. Persson, Robert E. Atkinson, Sidney F. Hauschild, Paula M. Kaplan, Brian D. Kuhnley, Keith E. Jasperson, Wondimeneh Tesfayesus, Christopher K. Thorp
  • Patent number: RE48025
    Abstract: In one embodiment, a method for maintaining patency of an upper airway of a patient to treat obstructive sleep apnea may include delivering an electrical stimulation to a portion of a superior laryngeal nerve via a nerve cuff when the nerve cuff is adjacent an external surface of the superior laryngeal nerve, the nerve cuff having a plurality of electrodes, wherein the nerve cuff is configured to be connected to an electrical stimulator via a stimulation lead.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: June 2, 2020
    Assignee: LivaNova USA, Inc.
    Inventors: Stephen L. Bolea, Thomas B. Hoegh, Bruce J. Persson, Robert E. Atkinson, Sidney F. Hauschild, Paula M. Kaplan, Brian D. Kuhnley, Keith E. Jasperson, Wondimeneh Tesfayesus, Christopher K. Thorp