Patents by Inventor Stephen L. Crook

Stephen L. Crook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazonaphtyridines
    Publication number: 20030096998
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: June 27, 2002
    Publication date: May 22, 2003
    Applicant: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom, Stephen L. Crooks, Philip D. Heppner, Gregory J. Marszalek, Peter V. Maye, Bryon A. Merrill, John W. Mickelson, Michael J. Rice
  • Amido ether substituted imidazoquinolines
    Publication number: 20030096835
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Application
    Filed: December 6, 2001
    Publication date: May 22, 2003
    Inventors: Stephen L. Crooks, George W. Griesgraber, Philip D. Heppner, Bryon A. Merrill
  • Urea substituted imidazoquinolines
    Patent number: 6541485
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain urea, thiourea, acylurea, or sulfonylurea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: April 1, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: Stephen L. Crooks, Bryon A. Merrill, Michael J. Rice
  • Imidazonaphthyridines
    Patent number: 6514985
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: February 4, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom, Stephen L. Crooks, Philip D. Heppner, Gregory J. Marszalek, Peter V. Maye, Bryon A. Merrill, John W. Mickelson, Michael J. Rice
  • Sulfonamido ether substituted imidazoquinolines
    Publication number: 20020193396
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and sulfonamide or sulfamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Application
    Filed: December 1, 2001
    Publication date: December 19, 2002
    Inventors: Stephen L. Crooks, George W. Griesgraber, Philip D. Heppner, Bryon A. Merrill, Ralph R. Roberts, Ai-Ping Wei
  • Process for preparing 1-substituted, 2-substituted 1H-imidazo[4, 5-c]quinoline-4-amines
    Patent number: 6465654
    Abstract: Methods of preparing 1-substituted, 2-substituted 1H-imidazo [4-5c]-quinolin-4-amines are disclosed. The compounds function as antiviral agents, they induce the biosynthesis of various cytokines including interferon, and they inhibit tumor formation in animal models.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: October 15, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • Amide substituted imidazoquinolines
    Patent number: 6451810
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: September 17, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: Patrick L. Coleman, Stephen L. Crooks, Kyle J. Lindstrom, Bryon A. Merrill, Michael J. Rice
  • Process for preparing 1-substituted, 2-substituted 1H-imidazo [4, 5-c] quinoline-4-amines
    Publication number: 20020115861
    Abstract: These compounds function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. This invention also provides intermediates for preparing such compounds, pharmaceutical compositions containing such compounds, and pharmacological methods of using such compounds.
    Type: Application
    Filed: October 9, 2001
    Publication date: August 22, 2002
    Applicant: 3M Innovative Properties Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
    Patent number: 6348462
    Abstract: 1-substituted, 2-substituted 1H-imidazo[4,5-c]-quinolin-4-amines are disclosed. These compounds function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. This invention also provides intermediates for preparing such compounds, pharmaceutical compositions containing such compounds, and pharmacological methods of using such compounds.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: February 19, 2002
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • Sulfonamide and sulfamide substituted imidazoquinolines
    Patent number: 6331539
    Abstract: Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain sulfonamide or sulfonamide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: December 18, 2001
    Assignee: 3M Innovative Properties Company
    Inventors: Stephen L. Crooks, Kyle J. Lindstrom, Bryon A. Merrill, Michael J. Rice
  • Imidazonaphthyridines
    Patent number: 6194425
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: February 27, 2001
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Kyle J. Lindstrom, Stephen L. Crooks, Philip D. Heppner, Gregory J. Marszalek, Peter V. Maye, Bryon A. Merrill, John W. Mickelson, Michael J. Rice
  • 1-substituted, 2-substituted 1H-imidazo[4,5-c] quinolin-4-amines
    Patent number: 5977366
    Abstract: 1-substituted, 2-substituted 1H-imidazo[4,5-c]-quinolin-4-amines are disclosed. These compounds function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. This invention also provides intermediates for preparing such compounds, pharmaceutical compositions containing such compounds, and pharmacological methods of using such compounds.
    Type: Grant
    Filed: April 14, 1998
    Date of Patent: November 2, 1999
    Assignee: 3M Innovative Properties Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • 1-substituted, 2-substituted 1H-imidazo?4,5-C!quinolin-4-amines
    Patent number: 5741909
    Abstract: 1-substituted, 2-substituted 1H-imidazo?4,5-c!-quinolin-4-amines are disclosed. These compounds function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. This invention also provides intermediates for preparing such compounds, pharmaceutical compositions containing such compounds, and pharmacological methods of using such compounds.
    Type: Grant
    Filed: January 28, 1997
    Date of Patent: April 21, 1998
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • Method of inhibiting leukotriene biosynthesis
    Patent number: 5612377
    Abstract: A method of inhibiting leukotriene biosynthesis, involving administering a compound of the formula: ##STR1## wherein M, R, R', R", and n are as defined herein. Also, a pharmaceutical composition involving such a compound and the use of such compounds in the manufacture of a pharmaceutical composition for inhibiting leukotriene biosynthesis.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: March 18, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Stephen L. Crooks, Bryon A. Merrill, Paul D. Wightman
  • 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
    Patent number: 5605899
    Abstract: 1-substituted, 2-substituted 1H-imidazo[4,5-c]-quinolin-4-amines are disclosed. These compounds function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. This invention also provides intermediates for preparing such compounds, pharmaceutical compositions containing such compounds, and pharmacological methods of using such compounds.
    Type: Grant
    Filed: December 12, 1994
    Date of Patent: February 25, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom
  • 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
    Patent number: 5389640
    Abstract: 1-substituted, 2-substituted 1H-imidazo[4,5-c]-quinolin-4-amines are disclosed. These compounds function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. This invention also provides intermediates for preparing such compounds, pharmaceutical compositions containing such compounds, and pharmacological methods of using such compounds.
    Type: Grant
    Filed: August 28, 1992
    Date of Patent: February 14, 1995
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: John F. Gerster, Stephen L. Crooks, Kyle J. Lindstrom