Patents by Inventor Stephen L. Karr, Jr.

Stephen L. Karr, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System for method for the modification and purification of proteins
    Patent number: 6359114
    Abstract: A system is described for conjugating, isolating, and purifying proteins. The system contains an ultrafiltration apparatus which is connected with a reaction vessel reservoir.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 19, 2002
    Assignee: Aphton Corp.
    Inventors: Stephen Grimes, Stephen L. Karr, Jr.
  • Method for the treatment and prevention of gastric and duodenal ulcer
    Patent number: 5866128
    Abstract: Immunogenic compositions useful for the treatment or prevention of gastric or duodenal ulcer disease are disclosed. The immunogenic compositions effectively operate by inducing antibodies in a subject which selectively neutralize specific peptide gastric hormones and inhibit the binding of the hormones to physiological receptors thus limiting the secretion of stomach acid. Pharmaceutical compositions comprising effective amounts of the immunogenic compositions and methods of treatment using the compositions are also disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 2, 1999
    Assignee: Aphton Corporation
    Inventors: Philip C. Gevas, Stephen L. Karr, Jr., Stephen Grimes, Richard L. Littenberg
  • Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease
    Patent number: 5622702
    Abstract: Immunogenic compositions useful for the treatment or prevention of gastric or duodenal ulcer disease are disclosed. The immunogenic compositions effectively operate by inducing antibodies in a subject which selectively neutralize specific peptide gastric hormones and inhibit the binding of the hormones to physiological receptors thus limiting the secretion of stomach acid. Pharmaceutical compositions comprising effective amounts of the immunogenic compositions and methods of treatment using the compositions are also disclosed.
    Type: Grant
    Filed: March 30, 1994
    Date of Patent: April 22, 1997
    Assignee: Aphton Corporation
    Inventors: Philip C. Gevas, Stephen L. Karr, Jr., Stephen Grimes, Richard L. Littenberg
  • Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease
    Patent number: 5023077
    Abstract: Immunogenic compositions useful for the treatment or prevention of gastric or duodenal ulcer disease are disclosed. The immunogenic compositions effectively operate by inducing antibodies in a subject which selectively neutralize specific peptide gastric hormones and inhibit the binding of the hormones to physiological receptors thus limiting the secretion of stomach acid. Pharmaceutical compositions comprising effective amounts of the immunogenic compositions and methods of treatment using the compositions are also disclosed.
    Type: Grant
    Filed: January 24, 1989
    Date of Patent: June 11, 1991
    Assignee: Aphton Corporation
    Inventors: Philip C. Gevas, Stephen L. Karr, Jr., Stephen Grimes, Richard L. Littenberg
  • Method for immunization against and treatment of infection by ectoparasites and endoparasites
    Patent number: 4891219
    Abstract: This invention relates to a method for the active or passive immunization of a vertebrate against ectoparasites and endoparasites, and a method of treating a vertebrate host infected by ectoparasites or endoparasites, comprising administering to the vertebrate an immunogen comprising one or more endocrine products of ectoparasites and endoparasites, coupled with an immunogenic carrier, or administering to the vertebrate, monoclonal antibodies capable of binding to the native form of the endocrine product.
    Type: Grant
    Filed: September 14, 1987
    Date of Patent: January 2, 1990
    Assignee: Aphton Corporation
    Inventors: Stephen L. Karr, Jr., Elizer Benjamini, Robert J. Scibienski, Stephen Grimes
  • Method for immunization against and treatment of infection by ectoparasites and endoparasites
    Patent number: 4814170
    Abstract: This invention relates to a method for the active or passive immunization of a vertebrate against ectoparasites and endoparasites, and a method of treating a vertebrate host infected by ectoparasites or endoparasites, comprising administering to the vertebrate an immunogen comprising one or more endocrine products of ectoparasites and endoparasites, coupled with an immunogenic carrier, or administering to the vertebrate, monoclonal antibodies formed to said immunogen.
    Type: Grant
    Filed: March 14, 1986
    Date of Patent: March 21, 1989
    Assignee: Aphton Corporation
    Inventor: Stephen L. Karr, Jr.