Patents by Inventor Stephen L. Mayo

Stephen L. Mayo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Computationally targeted evolutionary design
    Publication number: 20010051855
    Abstract: The invention relates to improved methods for directed evolution of polymers, including directed evolution of nucleic acids and proteins. Specifically, the methods of the invention include analytical methods for identifying “structurally tolerant” residues of a polymer. Mutations of these, structurally tolerant residues are less likely to adversely affect desirable properties of a polymer sequence. The invention further provides improved methods for directed evolution wherein the structurally tolerant residues of a polymer are selectively mutated. Computer systems for implementing analytical methods of the invention are also provided.
    Type: Application
    Filed: February 16, 2001
    Publication date: December 13, 2001
    Applicant: California Institute of Technology
    Inventors: Zhen-Gang Wang, Christopher A. Voigt, Stephen L. Mayo, Frances H. Arnold
  • Apparatus and method for automated protein design
    Publication number: 20010039480
    Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
    Type: Application
    Filed: April 4, 2001
    Publication date: November 8, 2001
    Applicant: The California Institute of Technology
    Inventors: Stephen L. Mayo, Bassil I. Dehiyat, D. Benjamin Gordon, Arthur Street, Yaoying Su
  • Apparatus and method for automated protein design
    Publication number: 20010032052
    Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
    Type: Application
    Filed: March 19, 2001
    Publication date: October 18, 2001
    Applicant: The California Institute of Technology
    Inventors: Stephen L. Mayo, Bassil I. Dahiyat, D. benjamin Gordon, Arthur Street, Yaoying Su
  • Apparatus and method for automated protein design
    Patent number: 6269312
    Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: July 31, 2001
    Assignee: California Institute of Technology
    Inventors: Stephen L. Mayo, Bassil I. Dahiyat, D. Benjamin Gordon, Arthur Street, Yaoying Su
  • Apparatus and method for automated protein design
    Patent number: 6188965
    Abstract: The present invention relates to apparatus and methods for quantitative protein design and optimization.
    Type: Grant
    Filed: April 10, 1998
    Date of Patent: February 13, 2001
    Assignee: California Institute of Technology
    Inventors: Stephen L. Mayo, Bassil I. Dahiyat, D. Benjamin Gordon, Arthur Street