Patents by Inventor Stephen L. NISHIMURA

Stephen L. NISHIMURA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEUTRALIZING ANTIBODIES TO THE ALPHA V BETA 8 INTEGRIN COMPLEX FOR IMMUNOTHERAPY
    Publication number: 20230331851
    Abstract: New antibodies and methods of use are described.
    Type: Application
    Filed: January 11, 2023
    Publication date: October 19, 2023
    Applicant: The Regents of the University of California
    Inventors: Stephen L. Nishimura, Jianlong Lou, James D. Marks, Jody L. Baron, Yifan Cheng, Shenping Wu, Anthony Cormier, Naoki Takasaka
  • ANTIBODIES THAT BIND INTEGRIN AVB8 AND USES THEREOF
    Publication number: 20230279119
    Abstract: Antibodies that bind to ?v?8 are provided.
    Type: Application
    Filed: January 11, 2023
    Publication date: September 7, 2023
    Applicant: The Regents of the University of California
    Inventors: Stephen L. Nishimura, Anthony Cormier, Saburo Ito, Jianlong Lou, James D. Marks, Yifan Cheng, Melody G. Campbell, Jody L. Baron
  • Antibodies that bind integrin AVB8 and uses thereof
    Patent number: 11608378
    Abstract: Antibodies that bind to ???8 are provided.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: March 21, 2023
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Stephen L. Nishimura, Anthony Cormier, Saburo Ito, Jianlong Lou, James D. Marks, Yifan Cheng, Melody G. Campbell, Jody L. Baron
  • Neutralizing antibodies to the alpha v beta 8 integrin complex for immunotherapy
    Patent number: 11591402
    Abstract: New antibodies and methods of use are described.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: February 28, 2023
    Assignee: The Regents of the University of California
    Inventors: Stephen L. Nishimura, Jianlong Lou, James D. Marks, Jody L. Baron, Yifan Cheng, Shenping Wu, Anthony Cormier, Naoki Takasaka
  • ANTIBODIES THAT BIND INTEGRIN AVB8 AND USES THEREOF
    Publication number: 20210277125
    Abstract: Antibodies that bind to ?v?8 are provided.
    Type: Application
    Filed: January 15, 2021
    Publication date: September 9, 2021
    Inventors: Stephen L. Nishimura, Anthony Cormier, Saburo Ito, Jianlong Lou, James D. Marks, Yifan Cheng, Melody G. Campbell, Jody L. Baron
  • NEUTRALIZING ANTIBODIES TO THE ALPHA V BETA 8 INTEGRIN COMPLEX FOR IMMUNOTHERAPY
    Publication number: 20210230279
    Abstract: New antibodies and methods of use are described.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 29, 2021
    Inventors: Stephen L. Nishimura, Jianlong Lou, James D. Marks, Jody L. Baron, Yifan Cheng, Shenping Wu, Anthony Cormier, Naoki Takasaka
  • Neutralizing antibodies to the ?v?8 integrin complex for immunotherapy
    Patent number: 10954304
    Abstract: Provided is an antibody that specifically binds human ?v?? and blocks binding of TGFp peptide to ?v?8, wherein the antibody binds to the specificity determining loop (SDL) of human ?8. In some embodiments, the antibody further binds to one, two, or all three of the human av-head domain, the al helix of human ?8, or the al helix of human ?8. In some embodiments, the antibody is humanized or chimeric. In some embodiments, the antibody is linked to a detectable label. Also provided is a method of enhancing an immune response in a human individual, comprising administering a sufficient amount of the antibody to the individual, thereby enhancing an immune response. Also provided are pharmaceutical compositions comprising the anti-?v?? antibodies or antigen-binding molecules thereof.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: March 23, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Stephen L. Nishimura, Jianlong Lou, James D. Marks, Jody L. Baron, Yifan Cheng, Shenping Wu, Anthony Cormier, Naoki Takasaka
  • NEUTRALIZING ANTIBODIES TO THE ALPHA V BETA 8 INTEGRIN COMPLEX FOR IMMUNOTHERAPY
    Publication number: 20190218298
    Abstract: Provided is an antibody that specifically binds human ?v?? and blocks binding of TGFp peptide to ?v?8, wherein the antibody binds to the specificity determining loop (SDL) of human ?8. In some embodiments, the antibody further binds to one, two, or all three of the human av-head domain, the al helix of human ?8, or the al helix of human ?8. In some embodiments, the antibody is humanized or chimeric. In some embodiments, the antibody is linked to a detectable label. Also provided is a method of enhancing an immune response in a human individual, comprising administering a sufficient amount of the antibody to the individual, thereby enhancing an immune response. Also provided are pharmaceutical compositions comprising the anti-?v?? antibodies or antigen-binding molecules thereof.
    Type: Application
    Filed: September 29, 2017
    Publication date: July 18, 2019
    Inventors: Stephen L. NISHIMURA, Jianlong LOU, James D. MARKS, Jody L. BARON, Yifan CHENG, Shenping WU, Anthony CORMIER, Naoki TAKASAKA