Patents by Inventor STEPHEN LENZINI

STEPHEN LENZINI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12042545
    Abstract: Disclosed are recombinant extracellular vesicles (EVs), compositions including modified EVs encapsulated in a matrix, methods for controlling the release of EVs from an encapsulating matrix, and methods of using the same in the treatment of disease.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: July 23, 2024
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Jae-Won Shin, Stephen Lenzini
  • Publication number: 20230279379
    Abstract: A method and microfluidic device for increasing the production of extracellular vesicles are provided which include the use of a cell-adhesive substrate for culturing extracellular-vesicle-producing cells, wherein the cell-adhesive substrate is a hydrogel having a Young's modulus of about 0.1 kPa to about 5 kPa and the hydrogel is functionalized with one or more cell adhesive peptides.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 7, 2023
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: STEPHEN LENZINI, JAE-WON SHIN
  • Publication number: 20220111068
    Abstract: Disclosed are recombinant extracellular vesicles (EVs), compositions including modified EVs encapsulated in a matrix, methods for controlling the release of EVs from an encapsulating matrix, and methods of using the same in the treatment of disease.
    Type: Application
    Filed: October 13, 2021
    Publication date: April 14, 2022
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: JAE-WON SHIN, STEPHEN LENZINI