Abstract: A wheel for a pneumatic tire has a rim with one monolithic bead seat and a removable beat seat. The removable bead seat has two halves that embrace the rim and engage a groove to retain the tire. The removable bead seat may have a second lip either monolithically formed or as a part of a separate retainer that bolts to the bead seat. The wheel may be made from aluminum alloy.

Abstract: A wheel for a pneumatic tire has a rim with one monolithic bead seat and a removable beat seat. The removable bead seat has two halves that embrace the rim and engage a groove to retain the tire. The removable bead seat may have a second lip either monolithically formed or as a part of a separate retainer that bolts to the bead seat. The wheel may be made from aluminum alloy.

Abstract: A wheel for a pneumatic tire has a rim with one monolithic bead seat and a removable beat seat. The removable bead seat has two halves that embrace the rim and engage a groove to retain the tire. The removable bead seat may have a second lip either monolithically formed or as a part of a separate retainer that bolts to the bead seat. The wheel may be made from aluminum alloy.

Abstract: The instant disclosure is directed towards shot shell configurations and methods of making the same.

Abstract: A wheel for a pneumatic tire has a rim with one monolithic bead seat and a removable beat seat. The removable bead seat has two halves that embrace the rim and engage a groove to retain the tire. The removable bead seat may have a second lip either monolithically formed or as a part of a separate retainer that bolts to the bead seat. The wheel may be made from aluminum alloy.

Abstract: A clip for mounting a fluid delivery device adjacent a wall of an enclosure is disclosed. In one embodiment, the device includes a base, a hook configured to support the base adjacent the wall, means for attaching a fluid delivery device to the base, and means for rotating the base. Additionally, a method for attaching a clip for mounting a fluid delivery device adjacent a toilet bowl is disclosed. The method includes securing a hook to a rim, engaging a tab of a base to an underside of the rim at an interface, and rotating the base in response to the interface to substantially engage the tab of the base with the underside of the rim.

Abstract: The present invention provides methods and devices for optical performance monitoring using co-located switchable fiber Bragg gratings (FBGs) in conjunction with a few detectors. This arrangement combines the merit of both tunable FBG filters and discrete detectors to achieve high spectral resolution, fast detection process and great dynamic range. By using parallel co-located FBGs in conjunction with a banded architecture, the tuning range of each FBG becomes much smaller (equivalent of ˜0.08% strain). As a result, not only does the update speed of the spectral characteristics for each channel become much faster, but it effectively eliminates the concern of FBG long-term reliability as well.

Abstract: The present invention provides assays and methods of compensating for changes in the dose-response curve of an assay where such changes are due to variations in a perturbing variable such as, but not limited to temperature. This is achieved by a two-step method, the first step of which involves measurements of the dose-response curve, and thus the individual assay parameters, at many different values of the perturbing variable, spanning the expected range of the perturbing variable. In the second step, unknown samples are assayed simultaneously with a known standard at a chosen analyte concentration. During this measurement, the value of the perturbing variable is unknown and the dose-response curve is therefore also unknown. The different dose-response curves from the first step are used to determine a mathematical relationship between the assay parameters and the assay signal of the known standard.

Abstract: A clip for mounting a fluid delivery device adjacent a wall of an enclosure is disclosed. In one embodiment, the device includes a base, a hook configured to support the base adjacent the wall, means for attaching a fluid delivery device to the base, and means for rotating the base. Additionally, a method for attaching a clip for mounting a fluid delivery device adjacent a toilet bowl is disclosed. The method includes securing a hook to a rim, engaging a tab of a base to an underside of the rim at an interface, and rotating the base in response to the interface to substantially engage the tab of the base with the underside of the rim.

Abstract: The present invention provides a microplate-based assay kit that incorporates all assay reagents and standards in a simple and efficient format and may be used in biochemical assays. The assay kit includes pre-filled, pre-sealed and barcoded microplates with a standard physical footprint for use in a microplate-based automated analyzer system which enables simple and efficient operation by an unskilled user via per-use factory-sealed and barcoded reagent and calibrator microplates. Such microplates allow the user to run a broad test menu without the need to monitor the arrangement and supply of internally stored reagents and standards, thus greatly simplifying the user experience and eliminating the need for highly skilled users.

Abstract: The present invention provides assays and methods of compensating for changes in the dose-response curve of an assay where such changes are due to variations in a perturbing variable such as, but not limited to temperature. This is achieved by a two-step method, the first step of which involves measurements of the dose-response curve, and thus the individual assay parameters, at many different values of the perturbing variable, spanning the expected range of the perturbing variable. In the second step, unknown samples are assayed simultaneously with a known standard at a chosen analyte concentration. During this measurement, the value of the perturbing variable is unknown and the dose-response curve is therefore also unknown. The different dose-response curves from the first step are used to determine a mathematical relationship between the assay parameters and the assay signal of the known standard.

Abstract: A heat storage unit (2) includes a body having a passage (12) formed therein through which a flowable product passes. A heatable element (10) is incorporated within the body of the heat storage unit (2) in thermal communication with the passage (12). Meanwhile, a heat-retentive material (8) is in thermal communication with the heatable element (10). The heatable element (10) includes either a magnetically-compatible material or a microwave-compatible material that is heated by locating the heatable element in a field (F) generated by a charging device (6), for example.

Abstract: The present invention provides a bar-code driven, completely automated, microplate-based analyzer system for performing chemical, biochemical or biological assays. The analyzer is a modular, bench-top instrument that compactly integrates subsystems for sample dispensing, liquid handling, microplate transport, thermal incubation, vortexing, solid phase separation and optical reading. An internal processor is included for automating the instrument, and a user interface to facilitate communication with the operator via a touch-sensitive liquid-crystal display (LCD), and communicating with a remote network via multiple protocols. The analyzer includes firmware resident within the processing system and the user interface allows the operator to select pre-defined assay batch protocols and the user interface is configured in such as way so as to restrict an operator from programming the firmware.

Abstract: A picture display frame includes front and rear sides. A recess is disposed within the rear side of the display frame. A volatile material holder is disposed within the recess of the rear side. The volatile material holder includes a reservoir and a vapor permeable membrane. A slot is disposed in a side wall of the display frame in communication with a portion of the recess. The portion of the recess is adapted to hold a decorative element.

Abstract: The present invention provides a method of performing a competitive assay for the detection and quantification of an analyte over an extended dynamic range. This is achieved by a multi-step sample addition method whereby different concentrations of sample are added at different times during the assay that produces a dose-response curve with multiple windows of detection. This multi-step sample addition method causes the dose-response curve of the composite assay to broaden, dramatically increasing the assay dynamic range.

Abstract: The present invention provides a method for the detection of an analyte in a specimen comprising two steps. First, the specimen is contacted with a substrate having receptors bound thereon, having higher affinity for cross-reactive substances than for the analyte, in order to increase the ratio of the analyte to the cross-reactive substances. Then, the treated specimen is assayed by using another receptor while decreasing the effects of the cross-reactive substance contained in the original specimen. The receptors in the first step are preferably molecular imprinted polymers that are capable of absorbing multiple cross-reactive substances.

Abstract: A display frame with a refill holder comprises a transparent block with front and rear faces. A U-shaped mounting member is attached to the rear face about an outer periphery of same. The U-shaped mounting member has an inwardly extending wall. A channel is formed in a space between the rear face and the inwardly extending wall. A protrusion is attached to the rear face of the frame, wherein the protrusion in combination with the inwardly extending wall are configured to distance the rear face from a support surface when the frame is in a substantially horizontal position and provide a substantially unimpeded air passage adjacent the rear face.

Abstract: An optical system is provided for achieving enhanced rejection of scattered excitation light and superior signal-to-noise performance when reading microplate wells. The optical system uses an axial configuration in which the excitation beam incident upon the sample propagates along the axis of the microplate well. Excitation light from a light source, such as a lamp or fiber optic bundle, is collimated into a beam using a lens. A reflective pick-off mirror is then used to reflect the collimated excitation beam upward along the well axis. A focusing lens, with a diameter exceeding the diameter of the collimated excitation beam, is used to focus the excitation beam in the well. The same broad lens is used to collimate the emitted fluorescent light, of which a large percentage propagates axially past the pick-off mirror towards a second focusing lens that focuses the emission beam onto the face of a fiber optic bundle.

Abstract: A volatile material dispensing system with a dispenser for providing controlled release of a volatile material, the dispenser being attached to a display frame, the display frame is secured to a base member that additionally retains an illuminating means. The illuminating means provides a pleasing ambiance in conjunction with the pleasant air freshener released by the dispenser.

Abstract: A volatile material dispensing system with a dispenser for providing controlled release of a volatile material, the dispenser being attached to a display frame, and having at least one protrusion. Protrusions are disposed on a face of the frame to distance the membrane from a delicate surface. The system prevents and/or hinders concentration of volatile material gases that could harm a delicate surface and resists tipping from a substantially vertical position.