Patents by Inventor Stephen Lindstrom
Stephen Lindstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10329630Abstract: Compositions and methods for detecting presence of an emerging influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are disclosed. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as a pandemic and/or emerging influenza virus subtype). Probes and primers are provided herein that permit the rapid detection and/or discrimination of pandemic influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.Type: GrantFiled: December 7, 2017Date of Patent: June 25, 2019Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Bo Shu, Stephen Lindstrom
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Patent number: 10196699Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: GrantFiled: July 23, 2018Date of Patent: February 5, 2019Assignee: The United States of America as represented by the Secretary of the Dept. of Health & Human ServicesInventors: Stephen Lindstrom, Lamorris Loftin
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Publication number: 20180371527Abstract: Primers, probes and kits for detection of live attenuated influenza vaccine (LAIV) virus strains are provided. Also provided are the assays for detecting LAIV.Type: ApplicationFiled: December 13, 2016Publication date: December 27, 2018Applicant: The United States of America as Represented by the Secretary of the Department of Health and Human SInventors: Bo SHU, Stephen LINDSTROM, Kai-Hui WU, LaShondra BERMAN, Christine WARNES
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Publication number: 20180327870Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: ApplicationFiled: July 23, 2018Publication date: November 15, 2018Applicant: The Government of the USA as represented by the Secretary of the Dept. of Health & Human ServicesInventors: Stephen Lindstrom, Lamorris Loftin
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Publication number: 20180265936Abstract: The present disclosure relates to compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also disclosed herein.Type: ApplicationFiled: May 25, 2018Publication date: September 20, 2018Applicant: The United States of America as represented by the Secretary, Dept. of Health and Human ServicesInventors: Bo Shu, Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Shannon L. Emery, Christine Warnes, Catharine McCord
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Patent number: 10036076Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: GrantFiled: June 15, 2016Date of Patent: July 31, 2018Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services, Center for Disease Control and PreventionInventors: Stephen Lindstrom, Lamorris Loftin
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Patent number: 10006097Abstract: Compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are provided. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.Type: GrantFiled: October 22, 2014Date of Patent: June 26, 2018Assignee: The United States of America, as represented by the Secretry, Department of Health and Human ServicesInventors: Bo Shu, Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Shannon L. Emery, Christine Warnes, Catharine McCord
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Publication number: 20180163277Abstract: Compositions and methods for detecting presence of an emerging influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are disclosed. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as a pandemic and/or emerging influenza virus subtype). Probes and primers are provided herein that permit the rapid detection and/or discrimination of pandemic influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.Type: ApplicationFiled: December 7, 2017Publication date: June 14, 2018Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human ServicesInventors: Bo Shu, Stephen Lindstrom
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Publication number: 20180080091Abstract: Primers, probes and kits for detection and lineage differentiation of influenza B virus strains are provided. Also provided are the corresponding assays and methods.Type: ApplicationFiled: September 22, 2017Publication date: March 22, 2018Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMANInventors: Shannon Lynn Emery, Stephen Lindstrom, Kai-Hui Wu, LaShondra Shealey Berman, Christine Marie Warnes, Bo Shu
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Patent number: 9607312Abstract: Methods and apparatus for increasing co-mailing discounts are disclosed. An example method includes determining a first number of first books associated with a first pool, the first books to be addressed for delivery within a geographic region associated with a postal discount. The example method further includes identifying a filler from a second pool to fill open pockets associated with the first pool. The filler corresponds to a first type of book associated with the second pool. The example method also includes identifying a second number of second books associated with the filler to be bundled with the first books when the first number of the first books is less than a threshold number of books for the postal discount. The first number of the first books combined with the second number of the second books is at least as great as the threshold number of books.Type: GrantFiled: March 14, 2013Date of Patent: March 28, 2017Assignee: LSC COMMUNICATIONS US, LLCInventor: Stephen Lindstrom
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Publication number: 20160289777Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: ApplicationFiled: June 15, 2016Publication date: October 6, 2016Applicant: The Government of the U.S.A. as represented by the Secretary of the Dept. of Health and Human ServicInventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
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Publication number: 20160251732Abstract: The present disclosure relates to compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also disclosed herein.Type: ApplicationFiled: October 22, 2014Publication date: September 1, 2016Inventors: Bo Shu, Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Shannon L. Emery, Christine Warnes, Catharine McCord
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Patent number: 9382592Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: GrantFiled: October 17, 2013Date of Patent: July 5, 2016Assignee: The United States of America as represented by the Secretary of the Department ofInventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
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Publication number: 20140278876Abstract: Methods and apparatus for increasing co-mailing discounts are disclosed. An example method includes determining a first number of first books associated with a first pool, the first books to be addressed for delivery within a geographic region associated with a postal discount. The example method further includes identifying a filler from a second pool to fill open pockets associated with the first pool. The filler corresponds to a first type of book associated with the second pool. The example method also includes identifying a second number of second books associated with the filler to be bundled with the first books when the first number of the first books is less than a threshold number of books for the postal discount. The first number of the first books combined with the second number of the second books is at least as great as the threshold number of books.Type: ApplicationFiled: March 14, 2013Publication date: September 18, 2014Applicant: R.R. Donnelley & Sons CompanyInventor: Stephen Lindstrom
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Publication number: 20140128279Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: ApplicationFiled: October 17, 2013Publication date: May 8, 2014Applicant: The Government of the United States of America as represented by the Secretary of the Department ofInventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
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Patent number: 8568981Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: GrantFiled: July 20, 2012Date of Patent: October 29, 2013Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and PreventionInventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
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Publication number: 20120283135Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: ApplicationFiled: July 20, 2012Publication date: November 8, 2012Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
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Patent number: 8241853Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: GrantFiled: August 13, 2008Date of Patent: August 14, 2012Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and PreventionInventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
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Publication number: 20090111089Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.Type: ApplicationFiled: August 13, 2008Publication date: April 30, 2009Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin