Patents by Inventor Stephen Lindstrom

Stephen Lindstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10329630
    Abstract: Compositions and methods for detecting presence of an emerging influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are disclosed. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as a pandemic and/or emerging influenza virus subtype). Probes and primers are provided herein that permit the rapid detection and/or discrimination of pandemic influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: June 25, 2019
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Bo Shu, Stephen Lindstrom
  • Patent number: 10196699
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: February 5, 2019
    Assignee: The United States of America as represented by the Secretary of the Dept. of Health & Human Services
    Inventors: Stephen Lindstrom, Lamorris Loftin
  • Publication number: 20180371527
    Abstract: Primers, probes and kits for detection of live attenuated influenza vaccine (LAIV) virus strains are provided. Also provided are the assays for detecting LAIV.
    Type: Application
    Filed: December 13, 2016
    Publication date: December 27, 2018
    Applicant: The United States of America as Represented by the Secretary of the Department of Health and Human S
    Inventors: Bo SHU, Stephen LINDSTROM, Kai-Hui WU, LaShondra BERMAN, Christine WARNES
  • Publication number: 20180327870
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Application
    Filed: July 23, 2018
    Publication date: November 15, 2018
    Applicant: The Government of the USA as represented by the Secretary of the Dept. of Health & Human Services
    Inventors: Stephen Lindstrom, Lamorris Loftin
  • Publication number: 20180265936
    Abstract: The present disclosure relates to compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also disclosed herein.
    Type: Application
    Filed: May 25, 2018
    Publication date: September 20, 2018
    Applicant: The United States of America as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Bo Shu, Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Shannon L. Emery, Christine Warnes, Catharine McCord
  • Patent number: 10036076
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: July 31, 2018
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services, Center for Disease Control and Prevention
    Inventors: Stephen Lindstrom, Lamorris Loftin
  • Patent number: 10006097
    Abstract: Compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are provided. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: June 26, 2018
    Assignee: The United States of America, as represented by the Secretry, Department of Health and Human Services
    Inventors: Bo Shu, Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Shannon L. Emery, Christine Warnes, Catharine McCord
  • Publication number: 20180163277
    Abstract: Compositions and methods for detecting presence of an emerging influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample, are disclosed. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as a pandemic and/or emerging influenza virus subtype). Probes and primers are provided herein that permit the rapid detection and/or discrimination of pandemic influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also provided.
    Type: Application
    Filed: December 7, 2017
    Publication date: June 14, 2018
    Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Bo Shu, Stephen Lindstrom
  • Publication number: 20180080091
    Abstract: Primers, probes and kits for detection and lineage differentiation of influenza B virus strains are provided. Also provided are the corresponding assays and methods.
    Type: Application
    Filed: September 22, 2017
    Publication date: March 22, 2018
    Applicant: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN
    Inventors: Shannon Lynn Emery, Stephen Lindstrom, Kai-Hui Wu, LaShondra Shealey Berman, Christine Marie Warnes, Bo Shu
  • Patent number: 9607312
    Abstract: Methods and apparatus for increasing co-mailing discounts are disclosed. An example method includes determining a first number of first books associated with a first pool, the first books to be addressed for delivery within a geographic region associated with a postal discount. The example method further includes identifying a filler from a second pool to fill open pockets associated with the first pool. The filler corresponds to a first type of book associated with the second pool. The example method also includes identifying a second number of second books associated with the filler to be bundled with the first books when the first number of the first books is less than a threshold number of books for the postal discount. The first number of the first books combined with the second number of the second books is at least as great as the threshold number of books.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 28, 2017
    Assignee: LSC COMMUNICATIONS US, LLC
    Inventor: Stephen Lindstrom
  • Publication number: 20160289777
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 6, 2016
    Applicant: The Government of the U.S.A. as represented by the Secretary of the Dept. of Health and Human Servic
    Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
  • Publication number: 20160251732
    Abstract: The present disclosure relates to compositions and methods for detecting presence of an influenza virus in a sample, such as a biological sample obtained from a subject or an environmental sample. In some embodiments, the compositions and methods can be used to quickly identify particular subtypes of influenza virus (such as seasonal or variant influenza subtype H3, influenza subtype H5, Eurasian influenza subtype H7, North American influenza subtype H7, and/or influenza subtype H9) present in a sample. Probes and primers are provided herein that permit the rapid detection and/or discrimination of influenza virus subtype nucleic acids in a sample. Devices (such as arrays) and kits for detection and/or discrimination of influenza virus subtype nucleic acids are also disclosed herein.
    Type: Application
    Filed: October 22, 2014
    Publication date: September 1, 2016
    Inventors: Bo Shu, Stephen Lindstrom, Kai-Hui Wu, LaShondra Berman, Shannon L. Emery, Christine Warnes, Catharine McCord
  • Patent number: 9382592
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: July 5, 2016
    Assignee: The United States of America as represented by the Secretary of the Department of
    Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
  • Publication number: 20140278876
    Abstract: Methods and apparatus for increasing co-mailing discounts are disclosed. An example method includes determining a first number of first books associated with a first pool, the first books to be addressed for delivery within a geographic region associated with a postal discount. The example method further includes identifying a filler from a second pool to fill open pockets associated with the first pool. The filler corresponds to a first type of book associated with the second pool. The example method also includes identifying a second number of second books associated with the filler to be bundled with the first books when the first number of the first books is less than a threshold number of books for the postal discount. The first number of the first books combined with the second number of the second books is at least as great as the threshold number of books.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 18, 2014
    Applicant: R.R. Donnelley & Sons Company
    Inventor: Stephen Lindstrom
  • Publication number: 20140128279
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Application
    Filed: October 17, 2013
    Publication date: May 8, 2014
    Applicant: The Government of the United States of America as represented by the Secretary of the Department of
    Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
  • Patent number: 8568981
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: October 29, 2013
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention
    Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
  • Publication number: 20120283135
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Application
    Filed: July 20, 2012
    Publication date: November 8, 2012
    Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
  • Patent number: 8241853
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Grant
    Filed: August 13, 2008
    Date of Patent: August 14, 2012
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention
    Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin
  • Publication number: 20090111089
    Abstract: Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.
    Type: Application
    Filed: August 13, 2008
    Publication date: April 30, 2009
    Inventors: Stephen Lindstrom, Alexander Klimov, Nancy Cox, Lamorris Loftin