Patents by Inventor Stephen Lye

Stephen Lye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MARKERS OF PRETERM BIRTH
    Publication number: 20170342495
    Abstract: The invention relates to novel markers of preterm birth, methods for assessing the status of preterm birth using the markers, and methods for the diagnosis and therapy of preterm birth.
    Type: Application
    Filed: May 10, 2017
    Publication date: November 30, 2017
    Inventors: Jan Heng, Stephen Lye, Craig Pennell
  • METHODS TO DIAGNOSE A REQUIRED REGULATION OF TROPHOBLAST INVASION
    Publication number: 20120064087
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-?3, receptors of cytokines of the TGf? family, or HIF-1?.
    Type: Application
    Filed: July 14, 2011
    Publication date: March 15, 2012
    Applicant: Mount Sinai Hospital
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • Method for diagnosing an increased risk of preeclampsia by measuring the level of HIF-?
    Patent number: 8007769
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-?3, receptors of cytokines of the TG? family, or HIF-1?.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: August 30, 2011
    Assignee: Mount Sinai Hospital
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • METHODS TO DIAGNOSE A REQUIRED REGULATION OF TROPHOBLAST INVASION
    Publication number: 20100291708
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-?3, receptors of cytokines of the TG? family, or HIF-1?.
    Type: Application
    Filed: May 21, 2010
    Publication date: November 18, 2010
    Applicant: Mount Sinai Hospital
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • Methods for early diagnosing of an increased risk of preeclampsia
    Patent number: 7754495
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-?3, receptors of cytokines of the TG? family, or HIF-1?.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: July 13, 2010
    Assignee: Mount Sinai Hospital
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • METHODS TO DIAGNOSE A REQUIRED REGULATION OF TROPHOBLAST INVASION
    Publication number: 20090098146
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-?3, receptors of cytokines of the TG? family, or HIF-1?.
    Type: Application
    Filed: October 16, 2008
    Publication date: April 16, 2009
    Applicant: Mount Sinai Hospital
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • Method for diagnosing increased risk of preeclampsia
    Patent number: 7445940
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-beta 3, receptors of cytokines of the TG beta family, or HIF-1 alpha.
    Type: Grant
    Filed: January 26, 2005
    Date of Patent: November 4, 2008
    Assignee: Mount Sinai Hospital
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • Markers of pre-term labor
    Publication number: 20080009552
    Abstract: The invention relates to novel markers of pre-term labor, methods for assessing the status of pre-term labor using the markers, and methods for the diagnosis and therapy of pre-term labor.
    Type: Application
    Filed: March 23, 2007
    Publication date: January 10, 2008
    Inventors: Craig Pennell, Stephen Lye
  • Methods and Compositions for Modulating a Steroid Receptor
    Publication number: 20070286806
    Abstract: Methods, compositions, and uses are provided for modulating a steroid receptor or process mediated by a steroid receptor in a cell by administering a polypyridimine tract binding protein-associated splicing factor (PSF) polypeptide, a polynucleotide encoding the polypeptide, an isolated complex of a PSF polypeptide and a steroid receptor, and/or an agonist or antagonist thereof, in an effective amount to modulate the steroid receptor or process. Particular aspects of the invention relate to detection, monitoring, modulation, treatment and/or prevention of the onset of labor.
    Type: Application
    Filed: January 14, 2005
    Publication date: December 13, 2007
    Applicant: Mount Sinai Hospital
    Inventors: Stephen Lye, Xuesen Dong
  • Markers of pre-term labor
    Publication number: 20060166242
    Abstract: The invention relates to novel markers of pre-term labor, methods for assessing the status of pre-term labor using the markers, and methods for the diagnosis and therapy of pre-term labor.
    Type: Application
    Filed: January 6, 2006
    Publication date: July 27, 2006
    Applicant: Mount Sinai Hospital
    Inventors: Craig Pennell, Stephen Lye
  • Methods to diagnose a required regulation of trophoblast invasion
    Publication number: 20050136468
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-beta 3, receptors of cytokines of the TG beta family, or HIF-1 alpha.
    Type: Application
    Filed: January 26, 2005
    Publication date: June 23, 2005
    Applicants: Mount Sinai Hospital, Martin Post
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • Methods to diagnose a required regulation of trophoblast invasion
    Patent number: 6863880
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-?3, receptors of cytokines of the TG? family, or HIF-1?.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: March 8, 2005
    Assignees: Mount Sinal Hospital, Martin Post
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • Configurable telephone line distribution modules for designating primary and secondary telephone lines
    Patent number: 6570965
    Abstract: Telephone line distribution apparatus are provided that permit easy user-selection of primary and secondary telephone lines without requiring physical rewiring of RJ plugs or receptacles. A telephone line distribution apparatus includes a first RJ connector, one or more second RJ connectors, and a switching device that allows a subscriber to designate which of a plurality of incoming telephone lines is the subscriber's primary line and secondary line. A switching device has various user-selectable configurations. When in a first configuration, a first incoming telephone line becomes the subscriber primary telephone line at one or more of the second RJ connectors. When the switching device is in a second configuration, a second incoming telephone line becomes the subscriber primary telephone line at one or more of the second RJ connectors. Additional incoming telephone lines can be designated as primary or secondary telephone lines in a similar manner.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: May 27, 2003
    Assignee: Home Director, Inc.
    Inventors: Larson J. Isely, Gary Deen, William J. Grasty, Jeffrey A. Hatley, Todd J. Honnigford, Larry M. Hicks, Jeffrey McLamb, Stephen Lye
  • Methods to diagnose a required regulation of trophoblast invasion
    Publication number: 20020110833
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-&bgr;3, receptors of cytokines of the TG&bgr; family, or HIF-1&agr;.
    Type: Application
    Filed: December 20, 2001
    Publication date: August 15, 2002
    Applicant: Mount Sinai Hospital Corporation
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye
  • Methods to diagnose a required regulation of trophoblast invasion
    Patent number: 6376199
    Abstract: Methods are provided for the diagnosis and treatment of patients with increased risk of preeclampsia. The methods involve measuring levels of TGF-&bgr;3, receptors of cytokines of the TG&bgr; family, or HIF-1&agr;.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: April 23, 2002
    Assignees: The Hospital for Sick Children (HSC), Mount Sinai Hospital Corporation
    Inventors: Isabella Caniggia, Martin Post, Stephen Lye