Patents by Inventor Stephen M. Shaw

Stephen M. Shaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted tetrahydrofurans as modulators of sodium channels
    Patent number: 11919887
    Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
    Type: Grant
    Filed: November 8, 2022
    Date of Patent: March 5, 2024
    Assignee: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Steven John Durrant, Nadia M. Ahmad, Elizabeth Mary Beck, Lidio Marx Carvalho Meireles, Ewa Iwona Chudyk, Gorka Etxebarria Jardi, Bhairavi Galan, Sara S. Hadida Ruah, Dennis James Hurley, Ronald Marcellus Knegtel, Timothy Donald Neubert, Joanne Louise Pinder, Joseph Pontillo, Robert Pullin, Yvonne Schmidt, David Matthew Shaw, Sarah Skerratt, Dean Stamos, Stephen Andrew Thomson, Anisa Nizarali Virani, Christopher Wray
  • PROCESSES FOR THE PREPARATION OF 5-HT2C RECEPTOR AGONISTS
    Publication number: 20150210625
    Abstract: The present invention relates to processes and intermediates useful in the preparation of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (lorcaserin), a serotonin (5-HT) receptor modulator that is useful in the treatment of, for example, central nervous system disorders, such as obesity.
    Type: Application
    Filed: December 23, 2014
    Publication date: July 30, 2015
    Inventors: John A. DeMattei, Carlos Marlon, Ryan O. Castro, Tsung-Hsun Chuang, Mark Allen Hadd, Xiao-Xiong Lu, Mark Macias, Stephen M. Shaw
  • Processes for the preparation of 5-HTreceptor agonists
    Patent number: 8952197
    Abstract: The present invention relates to processes and intermediates useful in the preparation of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (lorcaserin), a serotonin (5-HT) receptor modulator that is useful in the treatment of for example, central nervous system disorders, such as obesity.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: February 10, 2015
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: John A. DeMattei, Carlos Marlon, Ryan O. Castro, Tsung-Hsun Chuang, Mark Allen Hadd, Xiao-Xiong Lu, Mark Macias, Stephen M. Shaw
  • PROCESSES FOR THE PREPARATION OF 5-HT2C RECEPTOR AGONISTS
    Publication number: 20120142967
    Abstract: The present invention relates to processes and intermediates useful in the preparation of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (lorcaserin), a serotonin (5-HT) receptor modulator that is useful in the treatment of, for example, central nervous system disorders, such as obesity.
    Type: Application
    Filed: June 17, 2010
    Publication date: June 7, 2012
    Inventors: John A. DeMattei, Marlon Carlos, Ryan O. Castro, Tsung-Hsun Chuang, Mark Allen Hadd, Xiao-Xiong Lu, Mark Macias, Stephen M. Shaw