Abstract: The invention is a cleaning cartridge which includes a housing and a tube for injecting a compressed gas therethrough and into specific areas of an optical disk drive. The tube is removably connectable at one end to a compressed gas supply, and is aimed at the other end to direct gas exiting therefrom at both the objective lens, beam-directing prism or mirror, or other internal optical disk drive components when the cartridge is seated in the drive. Upon insertion of the cleaning cartridge into the optical disk drive in the usual manner for any optical disk cartridge, gas is released from the compressed gas source, through the tube, and into the optical disk drive. The use of such a cleaning cartridge provides for easy, effective cleaning of any internal optical disk drive component without the abrasion and potential inconveniences associated with mechanical brushing, wiping, or other techniques.