Abstract: Compounds of Formula (I): wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

Abstract: A biocidal material includes a carrier, a plurality of copper-containing glass particles, and at least one co-biocide selected from isothiazolinones, bicyclic oxazolidines, and bromine nitrogen-based compounds. A minimum bactericidal concentration (MBC) of a combination of the at least one co-biocide and the plurality of copper-containing glass particles is less than an MBC of the at least one co-biocide in the absence of the plurality of copper-containing glass particles.

Abstract: A computing system includes a network interface circuit structured to facilitate data transmission over a network, and at least one processing circuit configured to receive account information from a provider device via an input/output device of the provider device, the account information corresponding with a user account, generate a first code including a first unique identifier specific to the account information, the first code being configured to be captured by a user device to cause a browser or an application to launch on the user device, receive a user confirmation from the user device in response to the first code being captured by the user device, the user confirmation including the first unique identifier, determine the first unique identifier received with the user confirmation corresponds with the account information, and open the user account in response to confirming the first unique identifier corresponds with the account information.

Abstract: A compound of formula (I) or formula (II) including tautomeric or stereochemically isomeric forms thereof, wherein: R1 represents C1-20 alkyl, C2-20 alkenyl, C6-20 aryl, or C4-20 heterocyclyl, each optionally substituted with one or more Y groups, R2a to R2l each independently represents H, C1-10 alkyl, C2-10 alkenyl, C6-12 aryl, or C4-12 heterocyclyl, each optionally substituted with one or more Y groups, R3 represents H, C1-10 alkyl, C2-10 alkenyl, C6-12 aryl, or C4-12 heterocyclyl, each optionally substituted with one or more Y groups, X represents NH, S or O, each Y independently represents cyano, halogen, N3, —C(O)RZ, —C(0)0Rz, —0C(0)Rz, —C(0)NHZ, —NHC(O)Rz, —NHC(0)NHRZ, —NHC(NH)NHRZ, —NCH(0)0Rz, -0C(0)NHRz, -0S(0)2RZ, —S(0)2NHRZ, —NHS(0)2RZ, —SRZ, —NRZZ or —ORz and each Rz independently represents H, C1-10 alkyl, C2-10 alkenyl, C6-10 aryl, or C4-10 heterocyclyl; or an N-oxide thereof or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof; and wherein formula (I) e

Abstract: Described are polymerizable high energy light absorbing compounds of formula I: Wherein Y, Pg, R2, R3, R4, R5, and R6 are as described herein. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

Abstract: Disclosed are compounds of Formula 1, including all stereoisomers, N-oxides, and salts thereof, agricultural compositions containing them and their use as herbicides wherein R1, R2, R3, R4, R14, and X are as defined in the disclosure, A is selected from and R12, R13, n, X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, Y and Y1 are as defined in the disclosure.

Abstract: Various shaped abrasive particles are disclosed. Each shaped abrasive particle includes a body having at least one major surface and a side surface extending from the major surface.

Abstract: A biocidal material and method of forming is provided. The biocidal material includes a carrier and a plurality of treated copper-containing particles including a particle surface pre-treatment. The surface pre-treatment includes a copper-chelating material.

Abstract: A fault insertion device (FID) comprises a transceiver and an FPGA. The transceiver receives signals from a MIL-STD-1553/1760 communications bus. The FPGA evaluates the signals received from the communications bus against a set of rules stored by the FPGA. Based upon the set of rules, the FPGA can selectively modify messages received from the communications bus prior to transmission to a remote terminal or a bus controller that is configured to communicate on the communications bus.

Abstract: The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.

Abstract: Methods, systems, and computer-readable media for generating a statistically covaried machine learning model for performance measurement of service providers. The method receives a configuration file that includes one or more parameters associated with a plurality of individuals and parses it to generate and executing the database query on input data to generate sets of tabulated data of individuals of the plurality of individuals. The method next determines one or more measures of service providers listed in the configuration file using two or more tabulated data of individuals from the sets of tabulated data of individuals. The method finally generates a covaried machine learning model by training a machine learning model by statistically covarying measures and using them as training data.

Abstract: An aqueous barrier coat for formable cellulosic substrates comprises a blend of A) at least one aqueous polymer binder dispersion at 40 wt % to 95 wt %, B) at least one active filler at 3 wt % to 30 wt % and, C) one or more optional additives, such as wetting additives, dispersants, thickeners, defoamers, and crosslinkers. Crystallinity is present in at least one of the polymer binder dispersion and active filler particle. The resulting dried film has a shear storage modulus between 50° C. and 60° C. in the range of 1.5×106 to 1×109 Pascals, a shear storage modulus between 80° C. and 90° C. in the range of 2×105 to 5×107 Pascals, and a shear storage modulus between 100° C. and 110° C. is in the range of 5×103 to 1×106 Pascals. The total weight % of crystalline polymer binder and the crystalline active filler combined is greater than 50%.

Abstract: A method for processing data of an analytical instrument for analyzing biological samples is presented. The method comprises receiving instrument data from the analytical instrument at a data processing module communicatively connected with the analytical instrument, generating metadata from the received instrument data at the data processing module, applying a first encryption to the instrument data at the data processing module, applying a second encryption to the generated metadata at the data processing module, and transmitting the encrypted metadata and encrypted instrument data to a remote server. The remote server and the data processing module are communicatively connected. The method also comprises removing the second encryption from the metadata at the remote server and forwarding the instrument data encrypted by the first encryption from the remote server to a management system of the analytical instrument.

Abstract: The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.

Abstract: A utility vehicle includes a frame assembly defined by a lower frame assembly and an upper frame assembly coupled to the lower frame assembly. The frame assembly supports a plurality of body panels. A roof, front windshield, rear windshield, and doors may be coupled to the frame assembly to enclose the operator area.

Abstract: A method for processing data of an analytical instrument for analyzing biological samples is presented. The method comprises receiving instrument data from the analytical instrument at a data processing module communicatively connected with the analytical instrument, generating metadata from the received instrument data at the data processing module, applying a first encryption to the instrument data at the data processing module, applying a second encryption to the generated metadata at the data processing module, and transmitting the encrypted metadata and encrypted instrument data to a remote server. The remote server and the data processing module are communicatively connected. The method also comprises removing the second encryption from the metadata at the remote server and forwarding the instrument data encrypted by the first encryption from the remote server to a management system of the analytical instrument.

Abstract: Methods, systems, and computer-readable media for updating a machine learning model utilized in a search engine operation. The method identifies a set of search queries in stored search queries corresponding to a service and apply the identified set of search queries to the search engine to generate one or more search results for the service. Each search result has an assigned aggregate based on values of a set of parameters associated with the service. The method then analyzes the values of the set of parameters to determine a tradeoff point of each parameter to determine one or more weights to apply to the machine learning model based on the tradeoff points. The method stores the determined one or more weights and applies them to the machine learning model for a search query corresponding to the service.

Abstract: Methods, systems, and computer-readable media for updating a machine learning model utilized in a search engine operation. The method identifies a set of search queries in stored search queries corresponding to a service and apply the identified set of search queries to the search engine to generate one or more search results for the service. Each search result has an assigned aggregate based on values of a set of parameters associated with the service. The method then analyzes the values of the set of parameters to determine a tradeoff point of each parameter to determine one or more weights to apply to the machine learning model based on the tradeoff points. The method stores the determined one or more weights and applies them to the machine learning model for a search query corresponding to the service.

Abstract: Electric jacket systems and methods for extraction are described. A system may be arranged or arrangeable for electrically controlling a temperature of one or more extraction system components. The system may include a first plurality of thermoelectric devices, the first plurality arranged or arrangeable for coupling with a first extraction system component at multiple locations along the first extraction system component. The system may further include a controller operably coupled to the first plurality of thermoelectric devices, with the controller configured or configurable to establish or maintain at least a first target temperature by selectively applying or causing the selective application of electrical power to the first plurality of thermoelectric devices.