Abstract: The present disclosure provides, in some aspects, virus-like particle drug conjugate formulations and use of the conjugates for treating ocular tumors or lesions.

Abstract: A rechargeable bracket removable from a vehicle is presented. The rechargeable bracket has a power source coupled to the rechargeable bracket where the power source supplies power to the rechargeable bracket. The rechargeable bracket has a wiring apparatus and the wiring apparatus is coupled to the power source. A power storage apparatus is communicatively coupled to the wiring apparatus and is coupled to the power storage apparatus by a power storage connector. A lamp is coupled to the power storage apparatus and contained within the rechargeable bracket. An insertion apparatus is described as being coupled to the rechargeable bracket and securable to the vehicle. The rechargeable bracket further has a wireless communication apparatus which includes a wireless antenna. The wireless antenna being coupled to the wireless communication apparatus and sending and receiving signals from an external application. The external application may be executed on a smartphone or other computing device.

Abstract: In one aspect, the invention provides methods for determining the biological activity of heat shock proteins or heat shock protein-peptide complexes based on the ATPase activity or the multimeric structure of the heat shock proteins or heal shock protein-peptide complexes, and methods for screening agents that modulate the biological activity of heat shock proteins or heat shock protein-peptide complexes. In another aspect, the invention provides complexes, compositions and methods for enhancing the immunogenicity of a heat shock protein or a complex comprising a heal shock protein and an antigenic molecule.

Abstract: The present invention relates to using lectin or lectin-like molecules to promote oligomerization of a glycoprotein or an immunologically and/or biologically active complex comprising glycoproteins. In particular, the invention provides compositions of a molecular complex comprising lectin molecules and immunologically and/or biologically active molecules. Methods of making such molecular complexes and methods of use of the compositions comprising such molecular complexes for the prevention and treatment of diseases, particularly cancer and infectious diseases, and for eliciting an immune response in a subject, are also provided.