Patents by Inventor Stephen Moss

Stephen Moss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140155309
    Abstract: A method of preparing a component of a personal care bar, the method comprising: (a) providing a composition comprising an isethionate surfactant at a temperature of at least 20° C.; (b) combining the composition comprising the isethionate surfactant with a synthetic 5 wax and optional further components at a temperature of at least 120° C.; and (c) cooling the mixture obtained in step (b).
    Type: Application
    Filed: June 14, 2012
    Publication date: June 5, 2014
    Inventors: Phillip Loraine Cotrell, Philip Arie Matena, Stephen Moss O'Connor
  • Patent number: 8623802
    Abstract: An aqueous composition comprising: (a) an acyl isethionate of formula (I): wherein R1 is an alkyl or alkenyl group having from (7) to (21) carbon atoms and M+ is a cation; and (b) a further surfactant selected from nonionic surfactants, cationic surfactants and anionic surfactants other than those of formula (I); wherein component (a) and component (b) together comprise more than (12) wt % of the composition.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: January 7, 2014
    Assignee: Innospec Limited
    Inventors: Stephen Moss O'Connor, Phillip Lorraine Cotrell
  • Patent number: 8618034
    Abstract: An aqueous composition comprising: (a) an acyl isethionate of formula (I): wherein R1 is an alkyl or alkenyl group having from (7) to (21) carbon atoms and M+ a cation; and (b) an amphoteric, betaine or sultaine surfactant; wherein the weight ratio of component (a) to component (b) is more than 3:1.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: December 31, 2013
    Assignee: Innospec Limited
    Inventors: Stephen Moss O'Connor, Phillip Lorraine Cotrell
  • Patent number: 8598141
    Abstract: This disclosure relates to uridine diphosphate (UDP) derivatives, compositions comprising therapeutically effective amounts of those UDP derivatives and methods of using those derivatives or compositions in treating disorders that are responsive to ligands, such as agonists, of P2Y6 receptor, e.g., neuronal disorders, including neurodegenerative disorders (e.g., Alzheimer's disease) and traumatic CNS injury, as well as pain.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: December 3, 2013
    Assignee: Tufts University
    Inventors: Philip Haydon, Jinbo Lee, Jinghui Dong, Stephen Moss, Raquel Revilla-Sanchez
  • Publication number: 20130252919
    Abstract: This disclosure relates to uridine diphosphate (UDP) derivatives, compositions comprising therapeutically effective amounts of those UDP derivatives and methods of using those derivatives or compositions in treating disorders that are responsive to ligands, such as agonists, of P2Y6 receptor, e.g., neuronal disorders, including neurodegenerative disorders (e.g., Alzheimer's disease) and traumatic CNS injury, as well as pain.
    Type: Application
    Filed: March 8, 2013
    Publication date: September 26, 2013
    Applicant: TUFTS UNIVERSITY
    Inventors: Philip Haydon, Jinbo Lee, Jinghui Dong, Stephen Moss, Raquel Revilla-Sanchez
  • Publication number: 20130109610
    Abstract: An aqueous composition comprising: (a) an acyl isethionate of formula (I): wherein R1 is an alkyl or alkenyl group having from (7) to (21) carbon atoms and M+ a cation; and (b) an amphoteric, betaine or sultaine surfactant; wherein the weight ratio of component (a) to component (b) is more than 3:1.
    Type: Application
    Filed: March 25, 2011
    Publication date: May 2, 2013
    Applicant: INNOSPEC LIMITED
    Inventors: Stephen Moss O'Connor, Phillip Lorraine Cotrell
  • Publication number: 20130109611
    Abstract: An aqueous composition comprising: (a) an acyl isethionate of formula (I): wherein R1 is an alkyl or alkenyl group having from (7) to (21) carbon atoms and M+0 is a cation; and (b) a further surfactant selected from nonionic surfactants, cationic surfactants and anionic surfactants other than those of formula (I); wherein component (a) and component (b) together comprise more than (12) wt % of the composition.
    Type: Application
    Filed: March 25, 2011
    Publication date: May 2, 2013
    Applicant: INNOSPEC LIMITED
    Inventors: Stephen Moss O'Connor, Phillip Lorraine Cotrell
  • Publication number: 20120243769
    Abstract: The invention relates to methods of diagnosis, particularly methods of staging and diagnosing neurodegenerative diseases using images of cell death in the eye.
    Type: Application
    Filed: November 5, 2010
    Publication date: September 27, 2012
    Applicant: UCL BUSINESS PLC
    Inventors: Stephen Moss, Maria Francesca Cordeiro, Steven Dakin
  • Publication number: 20120231002
    Abstract: This invention relates to the field of molecular physiology. Specifically, this invention relates to the prevention and/or treatment of vasculoproliferative conditions, especially those of the eye and in the treatment of tumours that exhibit vascular proliferation. Levels of leucine-rich alpha-2-glycoprotein (Lrg1) have been demonstrated to be increased in patients suffering from such conditions and animal models of such conditions. Antagonists of Lrg1 can be used to prevent and/or treat vasculoproliferative conditions.
    Type: Application
    Filed: September 6, 2010
    Publication date: September 13, 2012
    Applicant: UCL Business PLC
    Inventors: John Greenwood, Stephen Moss, Xiaomeng Wang
  • Publication number: 20120115771
    Abstract: A pharmaceutical composition is provided comprising a vitamin E derivative, an anionic phopholipid-binding protein, an anionic phospholipid and a sterol. Also provided is a method for preparing a composition for delivering a cargo to a subject comprising a) forming liposomes from a vitamin E derivative, an anionic phospholipid-binding protein such as annexin, an anionic phospholipid such as phosphatidylserine and a sterol; and b) encapsulating the cargo in the liposomal composition.
    Type: Application
    Filed: March 29, 2010
    Publication date: May 10, 2012
    Applicant: UCL BUSINESS PLC
    Inventors: Francesca Cordeiro, Stephen Moss, Katy Coxon, James Duggan
  • Publication number: 20100284922
    Abstract: The invention relates to the use of a cell death marker labelled with a wavelength-optimised label for identifying cell death in the eye. Suitable cell death markers are the Annexins and fragments and derivatives thereof. The invention also relates to a pharmaceutical composition comprising a cell death marker labelled with a wavelength-optimised label and a method for monitoring cell death in the eye using a cell death marker labelled with a wavelength-optimised label.
    Type: Application
    Filed: December 15, 2008
    Publication date: November 11, 2010
    Applicant: UCL Business plc
    Inventors: Francesca Cordeiro, Stephen Moss, Frederick Fitzke
  • Publication number: 20100278747
    Abstract: The invention relates to a carrier for delivering agents to the posterior region of the eye, the carrier comprising a Vitamin E derivative, especially tocopherol. The carrier may also comprise a cell death marker, such as an annexin.
    Type: Application
    Filed: December 19, 2008
    Publication date: November 4, 2010
    Applicant: UCL BUSINESS PLC
    Inventors: Francesca Cordeiro, Stephen Moss
  • Publication number: 20070232657
    Abstract: The present invention relates to a novel benzamide derivative having pharmacological activity, to processes for its preparation, to compositions containing it and to its use in the treatment of diseases treatable by 5-HT4 receptor activation.
    Type: Application
    Filed: February 20, 2007
    Publication date: October 4, 2007
    Applicant: GLAXO GROUP LIMITED
    Inventors: Mahmood Ahmed, Neil Miller, Stephen Moss, Gareth Sanger
  • Publication number: 20070117820
    Abstract: Compounds of formula (I): or a pharmaceutically acceptable salt thereof, or a solvate thereof, wherein: P, P?, R1, R2, n, p, q, r, and s are as defined in the specification, processes for preparing such compounds, pharmaceutical compositions comprising such compounds and their use in therapy.
    Type: Application
    Filed: March 5, 2004
    Publication date: May 24, 2007
    Applicant: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Stephen Moss, Harshad Rami, Mervyn Thompson, David Witty
  • Publication number: 20070027139
    Abstract: This invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: September 23, 2004
    Publication date: February 1, 2007
    Inventors: Christopher Johnson, Stephen Moss, David Witty
  • Publication number: 20050222124
    Abstract: The invention provides compounds of formula (I) wherein A and B represent the groups —(CH2)m- and —(CH2)n-respectively; R1 represents hydrogen or C1-6alkyl; R2 represents hydrogen, halogen, hydroxy, cyano, nitro, hydroxyC1-6alkyl, trifluoromethyl, trifluoromethoxy, C1-6alkyl, C1-6alkoxy, C1-6alkoxyC1-6alkyl, C3-7cycloalkylC1-6alkoxy, —(CH2)pC3-6cycloalkyl, —(CH2)pC3-6cycloalkyloxy, —COC1-6alkyl, —SO2C1-6alkyl, —SOC1-6alkyl, —S—C1-6alkyl, C1-6alkylsulfonyloxy, C1-6alkylsulfonylC1-6alkyl, —CO2C1-6alkyl, —CO2NR7R8, —SO2NR7R8, C1-6alkylsulfonamido, C1-6alkylsulfonamidoC1-6alkyl, —(CH2)pNR7R8, C1-6alkylamidoC1-6alkyl, —(CH2)pNR7COR8, arylsulfonyl, arylsulfonyloxy, arylsulfonylC1-6alkyl, arylsulfonamido, arylcarboxamido, arylsulfonamidoC1-6alkyl, arylcarboxamidoC1-6alkyl, aroyl, aroylC1-6alkyl, arylC1-6alkanoyl, —SO2NR7R8, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heterocyclyl, or a group CONR7R8 or SO2NR7R8 wherein R7 and R8 together may be fused to form a 5-
    Type: Application
    Filed: February 13, 2003
    Publication date: October 6, 2005
    Inventors: Steven Bromidge, David Cooper, Ian Forbes, Andrew Gribble, Christopher Johnson, Andrew Plightfoot, Stephen Moss, Andrew Payne, Shahzad Rahman, David Witty
  • Publication number: 20050176759
    Abstract: Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: December 20, 2002
    Publication date: August 11, 2005
    Inventors: Mahmood Ahmed, Steven Bromidge, Ian Forbes, Andrew Gribble, Christopher Johnson, Francis King, Andrew Lightfoot, Gregor Macdonald, Stephen Moss, Mervyn Thompson, David Witty
  • Publication number: 20050124628
    Abstract: The present invention relates to novel quinoline compounds having pharmacological activity, to processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: March 25, 2003
    Publication date: June 9, 2005
    Inventors: Mahood Ahmend, Christopher Johnson, Martin Jones, Greor Macdonald, Stephen Moss, Mervyn Thompson, Charles Wade, David Witty
  • Publication number: 20050124626
    Abstract: The present invention relates to novel quinoline and aza indole compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: March 25, 2003
    Publication date: June 9, 2005
    Inventors: Christopher Johnson, Gregor Macdonald, Darren Mitchell, Stephen Moss, Mervyn Thompson, David Witty
  • Publication number: 20050090485
    Abstract: The present invention relates to novel sulfonamide compounds having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders.
    Type: Application
    Filed: February 13, 2003
    Publication date: April 28, 2005
    Inventors: Steven Bromidge, Christopher Johnson, Stephen Moss, Shahzad Rahman, David Witty