Abstract: A catheter includes a catheter body, a first lumen extending through the catheter body, one or more second lumens extending through the catheter body, and two or more capillaries extending from the catheter body and coupled to the second lumens. The first lumen performs at least one of receiving a sample of the blood from a vasculature of the patient or measuring a parameter of the blood. The second lumens receive a gas enriched liquid from a gas enriched liquid source. The capillaries receive the gas enriched liquid from the one or more second lumens and to simultaneously dispense respective streams of the gas enriched liquid directly into the vasculature, such that the streams of the gas enriched liquid intersect and mix with the blood in a region beyond an end of the catheter body and beyond the first lumen.

Abstract: An apparatus and method for blood oxygenation are provided. The apparatus includes a chamber having a first inlet to receive a fluid, e.g., physiologic saline; a second inlet to receive a gas, e.g., oxygen, from a gas supply; and an outlet coupled to a capillary assembly. An atomizer nozzle coupled to the first inlet creates within the chamber fine droplets of fluid into which the gas diffuses to create a gas-supersaturated fluid, which is removed via the outlet. The removed gas-supersaturated fluid mixes with blood within a liquid-to-liquid oxygenation assembly to form oxygenated blood for delivery to a patient. Alternately, the blood may be provided by a pump to a high pressure hollow fiber or other type membrane oxygenator within which oxygen diffuses across the membrane(s) and into the blood to form oxygenated blood, again for delivery to a patient or other site.