Abstract: The present invention relates to antibodies that bind Acinetobacter baumannii, and their use in the diagnosis of, and the prevention and treatment of, bacterial infection caused by Acinetobacter baumannii. In particular, the present invention relates to monoclonal antibodies that specifically bind at the bacterial wall of Acinetobacter baumannii bacteria, such as on, e.g., living bacteria.

Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.

Abstract: Presented herein are techniques that make use of objective measurements obtained in response to acoustic stimulation signals. More specifically, at least one measure of outer hair cell function and at least one measure of auditory nerve function are obtained from a tonotopic region of an inner ear of a recipient of a hearing prosthesis. The at least one measure of auditory nerve function and the least one measure of outer hair cell function are then analyzed relative to one another.

Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.

Abstract: Presented herein are techniques that make use of objective measurements obtained in response to acoustic stimulation signals. More specifically, at least one measure of outer hair cell function and at least one measure of auditory nerve function are obtained from a tonotopic region of an inner ear of a recipient of a hearing prosthesis. The at least one measure of auditory nerve function and the least one measure of outer hair cell function are then analyzed relative to one another.

Abstract: Presented herein are techniques that make use of objective measurements obtained in response to acoustic stimulation signals. More specifically, at least one measure of outer hair cell function and at least one measure of auditory nerve function are obtained from a tonotopic region of an inner ear of a recipient of a hearing prosthesis. The at least one measure of auditory nerve function and the least one measure of outer hair cell function are then analyzed relative to one another.

Abstract: Presented herein are techniques that make use of objective measurements obtained in response to acoustic stimulation signals. More specifically, at least one measure of outer hair cell function and at least one measure of auditory nerve function are obtained from a tonotopic region of an inner ear of a recipient of a hearing prosthesis. The at least one measure of auditory nerve function and the least one measure of outer hair cell function are then analyzed relative to one another.

Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.

Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.

Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.

Abstract: Presented herein are techniques that make use of objective measurements obtained in response to acoustic stimulation signals. More specifically, at least one measure of outer hair cell function and at least one measure of auditory nerve function are obtained from a tonotopic region of an inner ear of a recipient of a hearing prosthesis. The at least one measure of auditory nerve function and the least one measure of outer hair cell function are then analyzed relative to one another.

Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.

Abstract: An expert diagnosis system integrated in a hearing prosthesis system is configured to diagnosis, grade, and remediate inner ear crises. In particular, the expert diagnosis system analyzes combinations of in-situ measured inner ear potentials, obtained in response to electrical and/or acoustic stimulation, in order to identify crisis signatures and to correlate those crisis signatures to clinical symptoms of a specific type and cause of an inner ear crises (i.e., automatically diagnosis the inner ear crisis). The expert system is further configured to grade the severity of the identified clinical symptoms and initiate some form of remedial action to address the identified inner ear crisis.

Abstract: A method, including sequentially activating a plurality of respective electrode pairs of an implanted cochlear implant, at least one of the electrodes of the respective electrode pairs being a respective electrode of an electrode array implanted in a cochlea, thereby generating respective localized electric fields, concurrently respectively measuring, for the plurality of activated respective electrode pairs, an electrical characteristic between the respective electrodes of the respective electrode pairs resulting from the respective localized electric fields, thereby obtaining a measurement set, determining, from the measurement set, a distance between the electrode array and a wall of the cochlea.

Abstract: Presented herein are techniques that make use of objective measurements, such as acoustically-evoked inner ear responses, in the fitting process to determine the acoustic prescription (gain functions) that are used by an electro-acoustic hearing prosthesis to translate received sound signals into output acoustic simulation levels. More specifically, a plurality of acoustically-evoked inner ear responses are obtained from an inner ear of a recipient of an electro-acoustic hearing prosthesis. One or more input/output functions for at least one region of the inner ear are determined based on the plurality of acoustically-evoked inner ear responses and the one or more input/output functions are, in turn, used to determine one or more gain functions for use by the electro-acoustic hearing prosthesis.

Abstract: Presented herein are techniques for monitoring the insertion of an intra-cochlear stimulating assembly for the occurrence of one or more insertion stop conditions. The insertion stop conditions are detectable events indicating that movement of the stimulating assembly into a recipient's cochlea should be at least temporarily stopped. The insertion monitoring is based on objectively measured inner ear potentials, such as acoustically-evoked potentials.

Abstract: An expert diagnosis system integrated in a hearing prosthesis system is configured to diagnosis, grade, and remediate inner ear crises. In particular, the expert diagnosis system analyzes combinations of in-situ measured inner ear potentials, obtained in response to electrical and/or acoustic stimulation, in order to identify crisis signatures and to correlate those crisis signatures to clinical symptoms of a specific type and cause of an inner ear crises (i.e., automatically diagnosis the inner ear crisis). The expert system is further configured to grade the severity of the identified clinical symptoms and initiate some form of remedial action to address the identified inner ear crisis.

Abstract: Presented herein are in-situ techniques for monitoring a recipient's cochlea health to proactively identify (i.e., predict) changes to the recipient's cochlea health outside of a clinical setting. The cochlea health monitoring techniques presented herein obtain one or more cochlea health biomarkers associated with a recipient's cochlea health, such the recipient's residual hearing, and analyze these biomarkers to predict that a cochlea health change is likely to occur.

Abstract: An implant package for a cochlear implant, including stimulator electronics contained within a protective housing (2) and being coupled to an electrode array (9) for insertion into the cochlea of a patient, and being further coupled to a receiving and/or transmitting coil (8) enclosed within a protective casing, said protective housing being dimensioned and shaped to be capable of location within the mastoid cavity (C) of the patient nearer to the entry point of the electrode array to the cochlea, said further coupling being contained in a flexible connection between the protective housing (2) and the protective casing (8).

Abstract: An implant package for a cochlear implant, including stimulator electronics contained within a protective housing (2) and being coupled to an electrode array (9) for insertion into the cochlea of a patient, and being further coupled to a receiving and/or transmitting coil (8) enclosed within a protective casing, said protective housing being dimensioned and shaped to be capable of location within the mastoid cavity (C) of the patient nearer to the entry point of the electrode array to the cochlea, said further coupling being contained in a flexible connection between the protective housing (2) and the protective casing (8).