Patents by Inventor Stephen P. Madden

Stephen P. Madden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable label isotope tracing for untargeted data
    Patent number: 11817185
    Abstract: A method for analyzing samples utilizing stable label isotope tracing includes receiving mass spectrometry (MS) data generated by an MS system performing untargeted data acquisition on a plurality of samples, performing untargeted feature extraction on the unlabeled compound data to generate a data set of first extracted features, generating a plurality of empirical molecular formulas respectively corresponding to the first extracted features, performing targeted isotopologue extraction on the labeled compound data to generate a data set of second extracted features, wherein the targeted isotopologue extraction is based on the empirical molecular formula and retention time of each first extracted feature, and identifying one or more groups of isotopologues from the second extracted features.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: November 14, 2023
    Assignee: AGILENT TECHNOLOGIES, INC.
    Inventors: Stephen P. Madden, Steven M. Fischer
  • Stable Label Isotope Tracing for Untargeted Data
    Publication number: 20200365237
    Abstract: A method for analyzing samples utilizing stable label isotope tracing includes receiving mass spectrometry (MS) data generated by an MS system performing untargeted data acquisition on a plurality of samples, performing untargeted feature extraction on the unlabeled compound data to generate a data set of first extracted features, generating a plurality of empirical molecular formulas respectively corresponding to the first extracted features, performing targeted isotopologue extraction on the labeled compound data to generate a data set of second extracted features, wherein the targeted isotopologue extraction is based on the empirical molecular formula and retention time of each first extracted feature, and identifying one or more groups of isotopologues from the second extracted features.
    Type: Application
    Filed: April 10, 2020
    Publication date: November 19, 2020
    Inventors: Stephen P. Madden, Steven M. Fischer