Abstract: A cannula system includes: a tubular cannula shaft including an inner liner defining a blood flow lumen, an outer layer, and a metallic support structure positioned therebetween, where the inner liner includes an anticoagulant coating on an inner surface, and the outer layer includes a lubricious coating on an outer surface; a boot including a skin securement element for securing the cannula system to skin of a patient and a stepped distal ledge configurable to mitigate insertion into a blood vessel after insertion of the tubular cannula shaft into the blood vessel, where the tubular cannula shaft distal of the boot has a constant diameter configurable for insertion into the blood vessel; a transition section defining a clamp region; and a hub assembly including a blood infusion port, a blood reperfusion port, and an intervention port, each of the ports in fluid communication with the blood flow lumen.

Abstract: Expandable vascular introducer sheath devices, systems and method for low profile delivery, expansion to accommodate intravascular devices, and recovery for subsequent removal. The expandability features may be incorporated into other intravascular devices such as guide extension catheters, thrombus removal devices, etc.