Patents by Inventor Stephen Paul LATHROP

Stephen Paul LATHROP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Convergent and enantioselective total synthesis of Communesin analogs
    Patent number: 10918627
    Abstract: A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure of Formula (I): or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1-R8 and m, n, r, s, t, and u are as defined herein, is provided. Methods of making such compounds are also disclosed as are methods for the treatment of cancer, various infectious diseases, and abnormal cardiovascular function.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: February 16, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Mohammad Movassaghi, Stephen Paul Lathrop, Matthew W. Pompeo, Wen-Tau Timothy Chang
  • CONVERGENT AND ENANTIOSELECTIVE TOTAL SYNTHESIS OF COMMUNESIN ANALOGS
    Publication number: 20170333405
    Abstract: A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure of Formula (I): or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1-R8 and m, n, r, s, t, and u are as defined herein, is provided. Methods of making such compounds are also disclosed as are methods for the treatment of cancer, various infectious diseases, and abnormal cardiovascular function.
    Type: Application
    Filed: May 10, 2017
    Publication date: November 23, 2017
    Inventors: Mohammad MOVASSAGHI, Stephen Paul LATHROP, Matthew W. POMPEO, Wen-Tau Timothy CHANG