Abstract: Provided herein are solid forms comprising a compound of formula (I), or a stereoisomer, or a mixture of stereoisomers thereof, or a pharmaceutically acceptable salt thereof. Also provided herein are methods of synthesizing a compound of formula (I), pharmaceutical compositions comprising the same, and methods of treating, preventing, and managing various disorders using the compositions provided herein.

Abstract: Provided herein are solid forms comprising a compound of formula (I), or a stereoisomer, or a mixture of stereoisomers thereof, or a pharmaceutically acceptable salt thereof. Also provided herein are methods of synthesizing a compound of formula (I), pharmaceutical compositions comprising the same, and methods of treating, preventing, and managing various disorders using the compositions provided herein.

Abstract: A wheel adapter to convert a storage container to a wheeled storage container is provided. The wheel adapter comprises a mounting bracket attachable to the storage container. The mounting bracket comprises a first leg configured to engage a bottom surface of the storage container, and a second leg configured to engage a side surface of the storage container. The second leg comprises a wheel coupling. The wheel adapter also includes a wheel rotatably connected to the wheel coupling. The wheel is constructed and arranged for rotation about an axis to provide rolling support of the storage container on the ground.

Abstract: A wheel adapter to convert a storage container to a wheeled storage container is provided. The wheel adapter comprises a mounting bracket attachable to the storage container. The mounting bracket comprises a first leg configured to engage a bottom surface of the storage container, and a second leg configured to engage a side surface of the storage container. The second leg comprises a wheel coupling. The wheel adapter also includes a wheel rotatably connected to the wheel coupling. The wheel is constructed and arranged for rotation about an axis to provide rolling support of the storage container on the ground.

Abstract: A wheel adapter to convert a storage container to a wheeled storage container is provided. The wheel adapter comprises a mounting bracket attachable to the storage container. The mounting bracket comprises a first leg configured to engage a bottom surface of the storage container, and a second leg configured to engage a side surface of the storage container. The second leg comprises a wheel coupling. The wheel adapter also includes a wheel rotatably connected to the wheel coupling. The wheel is constructed and arranged for rotation about an axis to provide rolling support of the storage container on the ground.

Abstract: The present invention relates to a process for the manufacture of a chocolate product involving the use of hydrated salt, hydrated sugar or hydrated sugar alcohol in the underlying chocolate mass and comprising the steps of refining, conching and optionally tempering of the chocolate mass. The invention further relates to a chocolate product comprising a chocolate mass comprising certain weight proportions of hydratable salt, hydratable sugar or hydratable sugar alcohol, as obtainable by the process of the invention.

Abstract: A pet carrier and kennel which has an interior space for housing or storing animals. The interior space is fully enclosed on all sides by walls, a floor, and a roof to contain animals and related accessories such as blankets, beds, or bowls. The interior of the kennel can be accessed through an opening. A door is positioned in the opening to cover the opening. The door includes a locking mechanism that is easy to operate and can be opened from either side of the kennel.

Abstract: A wheel adapter to convert a storage container to a wheeled storage container is provided. The wheel adapter comprises a mounting bracket attachable to the storage container. The mounting bracket comprises a first leg configured to engage a bottom surface of the storage container, and a second leg configured to engage a side surface of the storage container. The second leg comprises a wheel coupling. The wheel adapter also includes a wheel rotatably connected to the wheel coupling. The wheel is constructed and arranged for rotation about an axis to provide rolling support of the storage container on the ground.

Abstract: The present invention relates to a process for the manufacture of a chocolate product involving the use of hydrated salt, hydrated sugar or hydrated sugar alcohol in the underlying chocolate mass and comprising the steps of refining, conching and optionally tempering of the chocolate mass. The invention further relates to a chocolate product comprising a chocolate mass comprising certain weight proportions of hydratable salt, hydratable sugar or hydratable sugar alcohol, as obtainable by the process of the invention.

Abstract: An electronic recording device that has an impact-activated playback function and a body adapted to allow the device sustained repeated physical impacts without damage to its internal components. In operation, a user records a message and then puts the device in motion by, for example, throwing or dropping it. The device plays back the message automatically upon impacting something. The message can any suitable type of recordable content, including audio content such a voice, music, noise, or any other sound and/or visual content, such as graphics, images, video or the like.

Abstract: A generally cylindrical container comprised of three parts including a top shell, a bottom shell, and a rotatable ring. The top and bottom shells are affixed to each other and hold the ring captive in a race formed by the outer sidewalls and annular retaining edges of the top and bottom shell. A discharge opening in the ring can be aligned with one or more openings in the sidewalls to allow passage of objects in or out of the container. The ring opening can similarly be aligned away from the sidewall opening(s) to prevent the passage of objects. The container disclosed herein represents a significant advance over known hand-operated containers because, among other things, it is simpler to manufacture, provides more reliable operation, and offers reduced friction against stored objects.

Abstract: A transcritical vapour compression refrigeration apparatus which comprises a compressor (1), a gas cooler (3), an economiser (7), an evaporator (9) and a refrigerant; the refrigerant being compressed in the compressor, heat being rejected from the compressed refrigerant at supercritical pressure in the gas cooler, the cooled compressed refrigerant being then expanded in a first stage to first temperature and pressure conditions in the economiser and then expanded in a second stage to second temperature and pressure conditions; a stream of refrigerant from the economiser at said first temperature and pressure conditions then being compressed in a first stream in the compressor; refrigerant at said second temperature and pressure conditions absorbing heat in the evaporator and then being compressed in a separate second stream in the compressor; said first and second compressed streams then being combined before passing to the gas cooler; or the first and second compressed streams passing through separate gas co

Abstract: An adjustable bed is provided having a lower frame (1) and an upper frame (3) mounted for longitudinal movement on the lower frame. A supporting surface (7, 8, 9, 10), including a back support member (7), is connected to the upper frame for pivotal movement about a transverse axis. The back support (7) is adjustable by an adjustment mechanism comprising two pairs of pivotally interconnected arms (17, 19), one of each pair being also pivoted to the lower frame (1) and the other arm of each pair being pivoted to the upper frame (3). The pivotal interconnections (18, 20) between the arms bear on the underside of the back support members, and a drive mechanism (13, 14, 15, 16) produces longitudinal movement of the upper frame with respect to the lower frame and, simultaneously, vertical movement of the pivotal interconnection (18).

Abstract: A multi-positional bed comprises at one end thereof a pair of pillars. One of the pillars is disposed at or near each side of the bed and at the opposite end a single pillar is disposed substantially on the longitudinal center line of the bed. The bed has a user-supporting frame, and respective mounting devices for mounting the frame to each of the pillars. Each mounting device is arranged to move lengthwise with respect to the respective pillar independently of the movement of the other mounting devices.

Abstract: A cannula assembly especially for medical use is disclosed which virtually eliminates coring during the piercing of a barrier. The cannula assembly includes a hollow cylindrical shank and a piercing tip removably mounted in and closing one end of the shank. Pressurized introduction of fluid through the shank forces the piercing tip out of engagement with the shank, placing opposite sides of the barrier in fluid communication.

Abstract: A sterile, closed drug delivery system (10) is provided comprising a flexible container (12), a capsule (22) coupled to the flexible container and a standard glass drug vial (36) positioned within the capsule. The flexible container has a liquid diluent therein. The capsule has supporting legs (32-35) which extend inwardly from the capsule to support the vial and also a highly flexible, pleated cap (28) which enables the drug vial to be manually moved relative to the supporting legs. The capsule is coupled to the flexible container by means of a hollow spike (54) located within the capsule and a frangible member (58) located within the flexible container, which frangible member allows fluid passage only when it is broken. Manual pressing of the pleated cap moves the drug vial downwardly onto the spike, piercing the stopper of the drug vial. Once the frangible member is broken, there is sterile communication between the drug vial and the liquid diluent contents of the flexible container.

Abstract: A sterile coupling enabling the selective establishment of a sterile pathway between two separate receptacles. A preferably injection molded plastic junction is made about at least the end portions of access means to each of the separate receptacles. The junction provides a sterile coupling so as to selectively bring the access means into pathway communication and thereby establish a sterile pathway between the receptacles through the access means. Also disclosed are methods for manufacturing a sterile coupling and methods for establishing a sterile pathway between the receptacles, as well as a method for low pressure injection molding.

Abstract: A sterile coupling enabling the selective establishment of a sterile pathway between two separate receptacles. A preferably injection molded plastic junction is made about at least the end portions of access means to each of the separate receptacles. The junction provides a sterile coupling so as to selectively bring the access means into pathway communication and thereby establish a sterile pathway between the receptacles through the access means. Also disclosed are methods for manufacturing a sterile coupling and methods for establishing a sterile pathway between the receptacles, as well as a method for low pressure injection molding.