Patents by Inventor Stephen Q. Zhou

Stephen Q. Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11090151
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: August 17, 2021
    Assignee: PERFECT IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Patent number: 10299914
    Abstract: A method of maintaining a hydrophilic intraocular lens in a foldable state without immersing the intraocular lens in liquid water includes the step of storing the foldable intraocular lens within a substantially airtight package containing a water reservoir not in direct contact with the lens.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: May 28, 2019
    Assignee: Carl Zeiss Meditec Production, LLC
    Inventors: Robert E. Glick, Stephen Q. Zhou
  • Patent number: 9999499
    Abstract: A preloaded intraocular lens (IOL) system/method utilizing haptic compression is disclosed. The disclosed system/method utilizes an IOL packaged in a compressed state that is inserted into a patient using a cartridge and lumen through which the IOL is advanced. Within this context the haptics to the IOL are wrapped around the IOL in a coplanar fashion during the loading of the IOL to permit the IOL to be shipped and stored in a compressed state. This compressed state is achieve by wrapping the haptics of the IOL during the manufacturing process to ensure that the IOL is properly aligned and thus delivered in a predetermined orientation within the patient's eye. This compressed packaging of the IOL permits a more uniform and consistent placement of the IOL in the patient and eliminates the potential for physician error during the critical IOL placement procedure.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 19, 2018
    Assignee: Carl Zeiss Meditec Production, LLC
    Inventors: Rick Aguilera, Bob Glick, Stephen Q. Zhou
  • Publication number: 20160278915
    Abstract: A method of maintaining a hydrophilic intraocular lens in a foldable state without immersing the intraocular lens in liquid water includes the step of storing the foldable intraocular lens within a substantially airtight package containing a water reservoir not in direct contact with the lens.
    Type: Application
    Filed: June 10, 2016
    Publication date: September 29, 2016
    Inventors: Robert E. Glick, Stephen Q. Zhou
  • Patent number: 9186242
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: November 17, 2015
    Assignee: PERFECT IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Publication number: 20150305933
    Abstract: A system is provided for noninvasive corneal refractive correction. The system includes an ortho-K lens specifically manufactured based on a topography of a cornea of a human eye for reshaping the cornea from a first configuration to a second configuration. The reshaping can be in situ or as a result of pre-laser treatment. The system also includes a laser device for initiating photochemical crosslinking within an internal layer of the cornea such that the crosslinked cornea remains substantially in the same shape as the second configuration without wearing the ortho-K lens. The laser device includes a laser source configured to produce output radiation in the form of light pulses, a scanner configured to distribute the light pulses in a predetermined pattern, and a light focusing objective configured to focus on an internal space of the cornea and deliver the light pulses into the internal space.
    Type: Application
    Filed: April 23, 2015
    Publication date: October 29, 2015
    Inventor: Stephen Q. Zhou
  • Patent number: 9107746
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: August 18, 2015
    Assignee: PERFECT IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Patent number: 9023257
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 5, 2015
    Assignee: Perfect IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Publication number: 20150114855
    Abstract: A method of maintaining a hydrophilic intraocular lens in a foldable state without immersing the intraocular lens in liquid water includes the step of storing the foldable intraocular lens within a substantially air tight package containing a water reservoir not in direct contact with the lens.
    Type: Application
    Filed: May 30, 2014
    Publication date: April 30, 2015
    Applicant: Aaren Scientific Inc.
    Inventors: Robert E. Glick, Stephen Q. Zhou
  • Publication number: 20140288644
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Application
    Filed: May 12, 2014
    Publication date: September 25, 2014
    Applicant: PERFECT IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Publication number: 20140249516
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Application
    Filed: May 12, 2014
    Publication date: September 4, 2014
    Applicant: PERFECT IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Publication number: 20140243443
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Application
    Filed: May 12, 2014
    Publication date: August 28, 2014
    Applicant: PERFECT IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Publication number: 20140239524
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Application
    Filed: May 12, 2014
    Publication date: August 28, 2014
    Applicant: PERFECT IP, LLC
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Publication number: 20140135920
    Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.
    Type: Application
    Filed: March 15, 2013
    Publication date: May 15, 2014
    Applicant: AAREN SCIENTIFIC, INC.
    Inventors: Ruth Sahler, Stephen Q. Zhou, Josef F. Bille
  • Publication number: 20140066946
    Abstract: A preloaded intraocular lens (IOL) system/method utilizing haptic compression is disclosed. The disclosed system/method utilizes an IOL packaged in a compressed state that is inserted into a patient using a cartridge and lumen through which the IOL is advanced. Within this context the haptics to the IOL are wrapped around the IOL in a coplanar fashion during the loading of the IOL to permit the IOL to be shipped and stored in a compressed state. This compressed state is achieve by wrapping the haptics of the IOL during the manufacturing process to ensure that the IOL is properly aligned and thus delivered in a predetermined orientation within the patient's eye. This compressed packaging of the IOL permits a more uniform and consistent placement of the IOL in the patient and eliminates the potential for physician error during the critical IOL placement procedure.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 6, 2014
    Applicant: Aaren Scientific, Inc.
    Inventors: Rick Aguilera, Bob Glick, Stephen Q. Zhou
  • Publication number: 20130103144
    Abstract: A lens for placement in a human eye, such as an intraocular lens, has at least some of its optical properties modified with a laser. The lens preferably contains at least 5% by weight UV absorber so commercially feasible rates of manufacture can be achieved. The laser forms modified loci in the lens where the modified loci have a different refractive index than the refractive index of the material before modification. The same laser modification technique can be used on the cornea in situ.
    Type: Application
    Filed: September 8, 2010
    Publication date: April 25, 2013
    Applicant: AAREN SCIENTIFIC INC.
    Inventors: Josef F. Bille, Stephen Q. Zhou
  • Patent number: 8133274
    Abstract: Intraocular lenses containing a photochromic agent, are disclosed. Specifically, the foldable intraocular lens of the present invention comprises an optic body made from a crosslinked material comprising at least one monomer, a crosslinker, a UV absorber, and a photochromic agent which has a maximum absorption peak of about 400-500 nm in its excited state. The lens has a glass transition temperature of about 37° C. or lower. Methods for making these intraocular lenses are also taught.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: March 13, 2012
    Assignee: Medennium, Inc.
    Inventors: Stephen Q. Zhou, Christopher D. Wilcox, Christine J. Liau
  • Publication number: 20090198326
    Abstract: An accommodative intraocular lens system for treating presbyopic is disclosed. The system includes a first lens having negative optic power adapted for placement in the posterior chamber of the eye and capable of moving forward and back along the optic axis; and a second lens having a positive optic power which is implanted within the capsular bag. The second lens can be the natural crystalline lens of the eye. The position of the first lens, forward or back relative to the second lens, focuses the eye for seeing distant or close-in objects.
    Type: Application
    Filed: January 31, 2008
    Publication date: August 6, 2009
    Applicant: MEDENNIUM INC.
    Inventors: Stephen Q. Zhou, Christopher D. Wilcox
  • Patent number: 6943204
    Abstract: A process for forming a surface modification on a polymer substrate and polymer substrates having such surface modifications. The process comprises the steps of absorbing a swelling monomer into the polymer substrate for a period of time in order to swell the polymer substrate; removing the swollen polymer from the swelling monomer; transferring the swollen polymer to a reaction mixture containing at least one functional monomer; polymerizing the functional monomer in the reaction mixture containing the swollen polymer substrate for a period of time; and removing the polymer from the reaction mixture. Because the surface modification produced by the process is a surface interpenetrating polymer network, the process is not sensitive to the reactive groups located on the surface of the polymer substrate. Further, the surface interpenetrating network bonds to the polymer substrate through caternary connections or other forms of chain entanglement and this is quite stable.
    Type: Grant
    Filed: August 26, 2003
    Date of Patent: September 13, 2005
    Assignee: Advanced Medical Optics Uppsala AB
    Inventors: Yading Wang, Robert van Boxtel, Stephen Q. Zhou
  • Patent number: 6884263
    Abstract: An accommodative intraocular lens is disclosed. The lens provides multiple focuses as the result of a bi-directional shift along the eye's optical axis, and also minimizes or prevents posterior chamber opacification. The lens includes a first component which consists of an optical body and a haptic body, a second component which is structurally adapted to maintain substantial contact with the posterior surface of the capsular bag of the eye (when implanted in the eye), and a transition zone connecting the first and second components. The method of implanting the lens in the eye and the method of making the lens are also disclosed.
    Type: Grant
    Filed: July 2, 2002
    Date of Patent: April 26, 2005
    Assignee: Medennium, Inc.
    Inventors: Igor Valyunin, Stephen Q. Zhou