Patents by Inventor Stephen R. Lindemann

Stephen R. Lindemann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromatin activity precipitation method and system
    Patent number: 10731202
    Abstract: Methods and systems for identifying binding sites in macromolecules using small molecule mimics of naturally occurring molecules is disclosed. A reactive probe is provided that mimics small molecule cofactors. A target macromolecule is irreversibly bound to the probe in vivo to selectively pull down or precipitate probe-bound macromolecules. The macromolecules may be, but are not limited to, DNA, RNA, and proteins.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: August 4, 2020
    Assignee: BATTELLE MEMORIAL INSTITUTE
    Inventors: Stephen R. Lindemann, Aaron T. Wright
  • Microbial consortia for programmable output via photoautotroph-heterotroph interactions
    Patent number: 10125348
    Abstract: Self-sustained, safe, stable and scalable microbial consortia (S5MicroCon) are described. The microbial consortia are regulated by photoautotroph-heterotroph interactions and RNA aptamer-based gene circuits. A rapid, high-throughput method for engineering RNA aptamer-based gene circuits (e.g. riboswitches) is also described.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: November 13, 2018
    Assignee: Battelle Memorial Institute
    Inventors: Alex S. Beliaev, Ryan S. McClure, Hans C. Bernstein, Stephen R. Lindemann, G. Chris Jansson
  • CHROMATIN ACTIVITY PRECIPITATION METHOD AND SYSTEM
    Publication number: 20170342469
    Abstract: Methods and systems for identifying binding sites in macromolecules using small molecule mimics of naturally occurring molecules is disclosed. A reactive probe is provided that mimics small molecule cofactors. A target macromolecule is irreversibly bound to the probe in vivo to selectively pull down or precipitate probe-bound macromolecules. The macromolecules may be, but are not limited to, DNA, RNA, and proteins.
    Type: Application
    Filed: November 11, 2015
    Publication date: November 30, 2017
    Applicant: Battelle Memorial Institute
    Inventors: Stephen R. Lindemann, Aaron T. Wright
  • MICROBIAL CONSORTIA FOR PROGRAMMABLE OUTPUT VIA PHOTOAUTOTROPH-HETEROTROPH INTERACTIONS
    Publication number: 20160201026
    Abstract: Self-sustained, safe, stable and scalable microbial consortia (S5MicroCon) are described. The microbial consortia are regulated by photoautotroph-heterotroph interactions and RNA aptamer-based gene circuits. A rapid, high-throughput method for engineering RNA aptamer-based gene circuits (e.g. riboswitches) is also described.
    Type: Application
    Filed: January 8, 2016
    Publication date: July 14, 2016
    Applicant: Battelle Memorial Institute
    Inventors: Alex S. Beliaev, Ryan S. McClure, Hans C. Bernstein, Stephen R. Lindemann, G. Chris Jansson