Patents by Inventor Stephen R. Martin
Stephen R. Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 12053517Abstract: Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.Type: GrantFiled: January 12, 2022Date of Patent: August 6, 2024Assignee: GILEAD SCIENCES, INC.Inventors: Jiani Li, Xinan Liu, Azure T. Makadzange, Stephen R. Martin, Hesham Shehata, Evguenia Svarovskaia
-
Publication number: 20240117017Abstract: Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.Type: ApplicationFiled: September 15, 2023Publication date: April 11, 2024Inventors: Xinan Liu, Azure T. Makadzange, Stephen R. Martin, Hesham Shehata, Evguenia Svarovskaia
-
Patent number: 11795210Abstract: Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.Type: GrantFiled: July 14, 2020Date of Patent: October 24, 2023Assignee: Gilead Sciences, Inc.Inventors: Xinan Liu, Azure T. Makadzange, Stephen R. Martin, Hesham Shehata, Evguenia Svarovskaia
-
Publication number: 20220218813Abstract: Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.Type: ApplicationFiled: January 12, 2022Publication date: July 14, 2022Inventors: Jiani Li, Xinan Liu, Azure T. Makadzange, Stephen R. Martin, Sarah Schmidt, Hesham Shehata, Felix Stemeseder, Evguenia Svarovskaia, Archana V. Boopathy
-
Publication number: 20220144923Abstract: Provided are methods for identifying patient populations infected with HIV that can be targeted by antibodies that bind to HIV gp120 CD4 binding site (CD4bs) region.Type: ApplicationFiled: November 9, 2021Publication date: May 12, 2022Inventors: Stephen R. Martin, Brian Moldt, Aiyappa Parvangada
-
Publication number: 20210017255Abstract: Provided are HIV-1 fusion polypeptides, polynucleotides encoding such fusion polypeptides, vectors expressing such fusion polypeptides for use in eliciting an immune response against HIV-1; pharmaceutical and immunogenic compositions and kits comprising such fusion polypeptides, polynucleotides or vectors, and methods of use in treating and/or preventing HIV-1. Further provided are methods for design of antiviral vaccines, including vaccines to elicit an immune response against HIV-1.Type: ApplicationFiled: July 14, 2020Publication date: January 21, 2021Inventors: Xinan Liu, Azure T. Makadzange, Stephen R. Martin, Hesham Shehata, Evguenia Svarovskaia
-
Patent number: 10794063Abstract: A tension rod anchor includes a collar that defines a ball race and a ball jack that includes a ball head that forms a swivel joint with the ball race. The ball jack also includes a threaded shaft that engages with a threaded socket of a hosel, which also includes a rod channel that receives a railing rod. A set screw engages with a threaded hole through a side of the hosel into the rod channel. The set screw engages with an anchor hole in the rod, without bearing against the threaded shaft, while the hosel is screwed onto the threaded shaft to tension the rod. Once the desired tension has been obtained, the set screw is screwed down further and tightened to secure the rod with the rod under tension. The swivel joints allow rod railings to be easily installed at angles and inclines.Type: GrantFiled: April 22, 2020Date of Patent: October 6, 2020Assignee: Clearview Handrails Inc.Inventor: Stephen R Martin
-
Patent number: 9954884Abstract: Embodiments of a system and method for a cyber modeling and simulation framework arc generally described herein. In some embodiments, an interface (212) for ingest of network and vulnerability data associated with a node of a targeted network, a network visualization device (232) for presenting the network data and the vulnerability data, and for creating a network model based on the network and vulnerability data, a threat analysis simulator (240) for launching threat attacks on the targeted network and for applying modeled defenses against the threat attacks, the threat analysis simulator producing simulation results (244) and a data farming module for performing data fanning on the simulation results using different scenarios to generate a farm of data for use in designing anti-cyber-attack strategies (280) for the targeted network.Type: GrantFiled: October 23, 2013Date of Patent: April 24, 2018Assignee: Raytheon CompanyInventors: Suzanne P. Hassell, Paul F. Beraud, III, Alen Cruz, Gangadhar Ganga, Brian J. Mastropietro, Travis C. Hester, David A. Hyde, Justin W. Toennies, Stephen R. Martin, Frank Pietryka, Niraj K. Srivastava
-
Patent number: 9424064Abstract: A system and method of deploying a network hopping adaptor is disclosed. In some embodiments, a network hopping adaptor may be configured to manipulate network traffic so as to change at least one network characteristic of the network traffic, and at least one network interface of a machine selected from a group of machines may be configured to send the network traffic to the network hopping adaptor. The network hopping adaptor may manipulate such characteristics as an IP address, a port number, an encryption algorithm or a compression algorithm. The group of machines may be deployed as virtual machines being executed by a virtualization server, and the network hopping adaptor may be implemented on another virtual machine being executed by the virtualization server. Alternatively, or in addition, the group of machines or the network hopping adaptor may be implemented as physical machines.Type: GrantFiled: August 1, 2014Date of Patent: August 23, 2016Assignee: Raytheon BBN Technologies Corp.Inventors: Gangadhar Ganga, Alen Cruz, Suzanne P. Hassell, Paul F. Beraud, III, Ledford J. Meadows, III, Stephen Patrick Marra, Jeanette M. Moody, Stephen R. Martin
-
Publication number: 20160183581Abstract: A process is provided for producing a substrate formulation comprising post-vaporization plant matter infused therein. The post-vaporization plant matter is gathered and saturated in a solvent to form a saturated mixture. The solvent is evaporated from the saturated mixture to form a reduced compound which is infused into a substrate thereby producing the post-vaporization plant matter infused substrate formulation.Type: ApplicationFiled: December 1, 2015Publication date: June 30, 2016Inventors: Stephen R. Martin, Stephen T.R. Martin
-
Patent number: 9368141Abstract: Accurately formed critical tolerance fit components are provided for fluid dynamic bearing motors, including disc drive memory systems. In an aspect, critical tolerance fit components are molded to a metal insert and include a portion of a hub, a disc seating surface, and a disc locating surface. The insert includes another portion of a hub, a sleeve, or a disc clamp retainer for a novel disc clamp. In an aspect, the plastic component is situated to cause the thermal expansion of the plastic to be restricted by the thermal expansion of a metal insert. Expensive machining of a stamped metal hub is minimized or eliminated by using the molded component portions. Strict component tolerances are provided as needed for perpendicularity relative to motor rotation for seating a disc with accurate flatness, a circumferential surface for centering the disc, and tight parallelism between a disc mounting surface and a center shaft.Type: GrantFiled: September 14, 2012Date of Patent: June 14, 2016Assignee: Seagate Technology LLCInventor: Stephen R. Martin
-
Publication number: 20160036691Abstract: A system and method of deploying a network hopping adaptor is disclosed. In some embodiments, a network hopping adaptor may be configured to manipulate network traffic so as to change at least one network characteristic of the network traffic, and at least one network interface of a machine selected from a group of machines may be configured to send the network traffic to the network hopping adaptor. The network hopping adaptor may manipulate such characteristics as an IP address, a port number, an encryption algorithm or a compression algorithm. The group of machines may be deployed as virtual machines being executed by a virtualization server, and the network hopping adaptor may be implemented on another virtual machine being executed by the virtualization server. Alternatively, or in addition, the group of machines or the network hopping adaptor may be implemented as physical machines.Type: ApplicationFiled: August 1, 2014Publication date: February 4, 2016Applicant: Raytheon BBN Technologies Corp.Inventors: Gangadhar Ganga, Alen Cruz, Suzanne P. Hassell, Paul F. Beraud, III, Ledford J. Meadows, III, Stephen Patrick Marra, Jeanette M. Moody, Stephen R. Martin
-
Publication number: 20150295948Abstract: Embodiments of a system and method for a cyber modeling and simulation framework arc generally described herein. In some embodiments, an interface (212) for ingest of network and vulnerability data associated with a node of a targeted network, a network visualization device (232) for presenting the network data and the vulnerability data, and for creating a network model based on the network and vulnerability data, a threat analysis simulator (240) for launching threat attacks on the targeted network and for applying modeled defenses against the threat attacks, the threat analysis simulator producing simulation results (244) and a data farming module for performing data fanning on the simulation results using different scenarios to generate a farm of data for use in designing anti-cyber-attack strategies (280) for the targeted network.Type: ApplicationFiled: October 23, 2013Publication date: October 15, 2015Inventors: Suzanne P. Hassell, Paul F. Beraud, III, Alen Cruz, Gangadhar Ganga, Brian J. Mastropietro, Travis C. Hester, David A. Hyde, Justin W. Toennies, Stephen R. Martin, Frank Pietryka, Niraj K. Srivastava
-
Publication number: 20090021859Abstract: Accurately formed critical tolerance fit components are provided for fluid dynamic bearing motors, including disc drive memory systems. In an aspect, critical tolerance fit components are molded to a metal insert and include a portion of a hub, a disc seating surface, and a disc locating surface. The insert includes another portion of a hub, a sleeve, or a disc clamp retainer for a novel disc clamp. In an aspect, the plastic component is situated to cause the thermal expansion of the plastic to be restricted by the thermal expansion of a metal insert. Expensive machining of a stamped metal hub is minimized or eliminated by using the molded component portions. Strict component tolerances are provided as needed for perpendicularity relative to motor rotation for seating a disc with accurate flatness, a circumferential surface for centering the disc, and tight parallelism between a disc mounting surface and a center shaft.Type: ApplicationFiled: July 19, 2007Publication date: January 22, 2009Inventor: Stephen R. Martin
-
Patent number: 6456456Abstract: A disk drive 100 capable of receiving a cartridge 20 having a disk 42 with a diameter of about 3.5 inches which can contain at least 105 megabytes of data includes an operating mechanism 112 for initiating and controlling the positioning of an actuator arm 176 upon which is mounted a read/write transducer 178. The position of a spindle motor 224 which is used to spin up the disk 42 contained in the cartridge 20 to an operating speed, the locking of the cartridge 20 in the disk drive 100 in an operating mode and the ejection of the cartridge 20 from the drive 100. The operating mechanism 112 can function to eject the cartridge 20 whether or not the drive 100 is powered up in order to be able to remove the cartridge 20 and transport it to another disk drive 100 or to a secured location in a plane substantially parallel to the disk 42 contained in the cartridge 20.Type: GrantFiled: May 1, 1998Date of Patent: September 24, 2002Assignee: Syquest Technology, Inc.Inventors: Alan D. Romig, Stephen R. Martin
-
Patent number: 6222700Abstract: A disc mounting system for mounting the discs of a disc drive in a fixed radial relationship to the hub of a spindle motor. The disc mounting system includes a compression spring member located between adjacent discs in the disc stack. The compression spring member has a circular cross-section, and forms a wave shape such as a sinsoidal wave shape encircling the hub of the spindle motor. When the discs are positioned in an intended relationship relative to the hub, high and low peaks on the compression spring member engage chamfers adjacent the bore of the discs, and act to center the discs relative to the spindle motor hub to prevent shifting of the discs relative to the spindle motor hub due to applied mechanical shocks and differential thermal expansion of disc stack elements.Type: GrantFiled: November 16, 1998Date of Patent: April 24, 2001Assignee: Seagate Technology LLCInventors: Stephen R. Martin, Thomas M. Durrum
-
Patent number: 5836071Abstract: A method for temporarily packaging a semiconductor die, includes attaching the semiconductor die (40) to a die support (60) in a cavity (58) of package housing (56) with an adhesive (52) that will cures at a first low temperature and volatilizes at a second, higher temperature that is less than the temperature that will drive diffusions in the die deeper and change the electrical characteristics of the die. A reverse bonding process is used to form a first wedge bond with a relatively soft wire (88) on a conductive pad (62) extending into cavity (58) and a second wedge bond on a bond pad (41) on die (40). The wedge tool (76) used to make the wedge bonds has a front radius which is larger than that on conventional wedge tools, so that the cross-sectional area of the bond heel (91) is increased. The increased cross-sectional area and soft wire permit the wire to be removed from the bond pad (41) without breaking the wire or significantly damaging the bond pad.Type: GrantFiled: December 26, 1996Date of Patent: November 17, 1998Assignee: Texas Instrument IncorporatedInventors: Robert J. Falcone, Stephen R. Martin
-
Patent number: 5442305Abstract: A diagnostic apparatus for testing devices such as computer systems, and computer system components such as disk drives or printers. The device comprises a main unit, the main unit having a central processing unit for executing instructions, issuing commands, and receiving data from a first device. The apparatus also has a first peripheral unit coupled to the main unit, the first peripheral unit having ports for interfacing with the first device, the first peripheral unit being interchangeable with a second peripheral unit for interfacing with a second device. The apparatus also comprises a first non-volatile memory unit coupled to the main unit. The first non-volatile memory unit comprising a first set of tests for the first device, the first non-volatile memory unit being interchangeable with a second non-volatile memory unit comprising a second set of tests for a second device. These interchangeable parts are provided so that the user may test various types of hardware.Type: GrantFiled: September 14, 1994Date of Patent: August 15, 1995Assignee: Apple Computer, Inc.Inventors: Stephen R. Martin, Randall O. Mooney, Jr.
-
Patent number: 5422775Abstract: A cartridge 20 for a disk drive 130 includes a door 44 which can be urged from a closed position to an opened position which is substantially within the cartridge 20 and located in a plane substantially parallel to the disk 42 contained in the cartridge 20. The cartridge 20 includes a mounting mechanism 48 for accomplishing the motion of the door 44 from the closed to the opened position and a locking mechanism 50 for locking the door 44 in the closed position. Further, the cartridge 20 includes a groove 52 which extends rearwardly and across the cartridge in order to lockingly engage the cartridge in the drive 130.Type: GrantFiled: October 12, 1993Date of Patent: June 6, 1995Assignee: SyQuest Technology, Inc.Inventor: Stephen R. Martin
-
Patent number: D902700Type: GrantFiled: June 26, 2020Date of Patent: November 24, 2020Assignee: Clearview Handrails Inc.Inventor: Stephen R Martin