Patents by Inventor Stephen R. PRIEBE

Stephen R. PRIEBE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRUG COMPOUND AND PURIFICATION METHODS THEREOF
    Publication number: 20220024965
    Abstract: The invention provides a method of preparing a lyophilized pharmaceutical composition containing a compound described herein or a pharmaceutically-acceptable salt thereof. The process comprises dissolving the compound in a solvent comprising dimethylsulfoxide and optionally one or more co-solvents to form a solution, and then removing the solvent and any co-solvents by a freeze-drying process. Also provided by the invention are lyophilized pharmaceutical compositions and their use in medicine and in particular in the treatment of cancer.
    Type: Application
    Filed: February 26, 2021
    Publication date: January 27, 2022
    Inventors: Rajashree JOSHI-HANGAL, Nipun DAVAR, Stephen R. PRIEBE
  • Drug compound and purification methods thereof
    Patent number: 10858386
    Abstract: The invention provides a method of preparing a lyophilized pharmaceutical composition containing a compound described herein or a pharmaceutically-acceptable salt thereof. The process comprises dissolving the compound in a solvent comprising dimethylsulfoxide and optionally one or more co-solvents to form a solution, and then removing the solvent and any co-solvents by a freeze-drying process. Also provided by the invention are lyophilized pharmaceutical compositions and their use in medicine and in particular in the treatment of cancer.
    Type: Grant
    Filed: November 5, 2019
    Date of Patent: December 8, 2020
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Rajashree Joshi-Hangal, Nipun Davar, Stephen R. Priebe
  • DRUG COMPOUND AND PURIFICATION METHODS THEREOF
    Publication number: 20200172565
    Abstract: The invention provides a method of preparing a lyophilized pharmaceutical composition containing a compound described herein or a pharmaceutically-acceptable salt thereof. The process comprises dissolving the compound in a solvent comprising dimethylsulfoxide and optionally one or more co-solvents to form a solution, and then removing the solvent and any co-solvents by a freeze-drying process. Also provided by the invention are lyophilized pharmaceutical compositions and their use in medicine and in particular in the treatment of cancer.
    Type: Application
    Filed: November 5, 2019
    Publication date: June 4, 2020
    Inventors: Rajashree JOSHI-HANGAL, Nipun DAVAR, Stephen R. PRIEBE
  • Drug compound and purification methods thereof
    Patent number: 10519190
    Abstract: The invention provides a method of preparing a lyophilized pharmaceutical composition containing a compound described herein or a pharmaceutically-acceptable salt thereof. The process comprises dissolving the compound in a solvent comprising dimethylsulfoxide and optionally one or more co-solvents to form a solution, and then removing the solvent and any co-solvents by a freeze-drying process. Also provided by the invention are lyophilized pharmaceutical compositions and their use in medicine and in particular in the treatment of cancer.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: December 31, 2019
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Rajashree Joshi-Hangal, Nipun Davar, Stephen R. Priebe
  • DRUG COMPOUND AND PURIFICATION METHODS THEREOF
    Publication number: 20190085018
    Abstract: The invention provides a method of preparing a lyophilized pharmaceutical composition containing a compound described herein or a pharmaceutically-acceptable salt thereof. The process comprises dissolving the compound in a solvent comprising dimethylsulfoxide and optionally one or more co-solvents to form a solution, and then removing the solvent and any co-solvents by a freeze-drying process. Also provided by the invention are lyophilized pharmaceutical compositions and their use in medicine and in particular in the treatment of cancer.
    Type: Application
    Filed: August 2, 2018
    Publication date: March 21, 2019
    Inventors: Rajashree JOSHI-HANGAL, Nipun DAVAR, Stephen R. PRIEBE