Abstract: Antibodies, and antigen-binding fragments thereof, that specifically bind to bone morphogenetic protein-9 (BMP9) are provided. Embodiments include uses, and associated methods of using the antibodies, and antigen-binding fragments thereof.

Abstract: Manifold for a medical/surgical waste collection assembly. A shell includes a proximal end base, and a lip extending proximally from the proximal end base. The lip extends around an outlet opening defined in the proximal end base that is off-centered to a longitudinal axis of the shell. A cap including a cap head is coupled to a side wall of the shell. A drip stop may be seated within a space defined by the lip to cover the outlet opening. An arcuate section of the lip may be flush with an adjacent section of the side wall. The cap head may define a through hole, and a flapper valve unit may be coupled to the cap head with another component having ears extending through the through hole. A fence may extend from the cap head and configured to be grasped by a user.

Abstract: Methods of assembling a manifold for a medical waste collection system. A flapper valve unit is secured to a head of a cap. A filter element is positioned within a shell. Basket hands of the filter element are fitted between first pairs of ribs of the cap skirt. Fingers of the shell are fitted between second pairs of ribs of the cap skirt. The cap is secured to the shell to cover an open distal end of the shell. A drip stop is secured to the proximal end base of the shell to seat within the outlet opening. Ears may be fitted through holes defined by the flapper valve unit and cap holes defined by the cap so as to snap lock to the head of the cap. The hub of the flapper valve unit may be compressed with the ears snap locked to the head of the cap.

Abstract: Methods of assembling a manifold for a medical waste collection system. A flapper valve unit is secured to a head of a cap. A filter element is positioned within a shell. Basket hands of the filter element are fitted between first pairs of ribs of the cap skirt. Fingers of the shell are fitted between second pairs of ribs of the cap skirt. The cap is secured to the shell to cover an open distal end of the shell. A drip stop is secured to the proximal end base of the shell to seat within the outlet opening. Ears may be fitted through holes defined by the flapper valve unit and cap holes defined by the cap so as to snap lock to the head of the cap. The hub of the flapper valve unit may be compressed with the ears snap locked to the head of the cap.

Abstract: Methods of assembling a manifold for a medical waste collection system. A flapper valve unit is secured to a head of a cap. A filter element is positioned within a shell. Basket hands of the filter element are fitted between first pairs of ribs of the cap skirt. Fingers of the shell are fitted between second pairs of ribs of the cap skirt. The cap is secured to the shell to cover an open distal end of the shell. A drip stop is secured to the proximal end base of the shell to seat within the outlet opening. Ears may be fitted through holes defined by the flapper valve unit and cap holes defined by the cap so as to snap lock to the head of the cap. The hub of the flapper valve unit may be compressed with the ears snap locked to the head of the cap.

Abstract: A personal protection system including a garment configured for attachment to a helmet, wherein the garment defines a barrier between a wearer and an environment. The system includes a control mount integral to the garment and at least partially disposed on the environment side and the wearer side of the barrier. The system may include an emitter and a sensor configured to detect a signal output by the emitter. The control mount may comprise a lens configured to transmit the signal from the emitter through the garment. A control member may be coupled to the control mount and configured to be manipulated by the wearer. When manipulated by the wearer, the control member may distort and/or disrupt the transfer of the signal through the lens that is detected by the sensor. The sensor may provide a sensor input signal based on the signal detected from the emitter.

Abstract: Methods of assembling a manifold for a medical waste collection system. A flapper valve unit is secured to a head of a cap. A filter element is positioned within a shell. Basket hands of the filter element are fitted between first pairs of ribs of the cap skirt. Fingers of the shell are fitted between second pairs of ribs of the cap skirt. The cap is secured to the shell to cover an open distal end of the shell. A drip stop is secured to the proximal end base of the shell to seat within the outlet opening. Ears may be fitted through holes defined by the flapper valve unit and cap holes defined by the cap so as to snap lock to the head of the cap. The hub of the flapper valve unit may be compressed with the ears snap locked to the head of the cap.

Abstract: A manifold apparatus and method of opening a valve in a medical/surgical waste collection unit. The manifold includes a base at a proximal end with the base defining an opening off center from an axis of the manifold. The manifold further includes two arcuately spaced tabs, each subtending arcs having different arcuate lengths. The manifold is positioned such that the tabs mate with at least two slots of a lock ring of the waste collection unit so as to cause the opening of the manifold to be, upon insertion into a bore of the waste collection unit, in a specific rotational alignment in the bore. The manifold is rotated within the bore to cause a valve disk to move between a first position in which the valve disk blocks fluid flow through the receiver and a second position in which the valve disk allows fluid flow through the receiver.

Abstract: A specimen collection cassette for a medical fluid collection system. A housing defines a first void space and a second void space, and an outlet opening in fluid communication with the first and second void spaces. An aperture may be within a wall separating the first and second void spaces with the aperture providing fluid communication between the first and second void spaces. First and second fittings receive a suction line for drawing fluid into the first and second void spaces, respectively. A fluid communication path is established from the first fitting to the outlet opening through the first void space, aperture, and the second void space, and a bypass fluid communication path is established from the second bore to the outlet opening through the second void space. The cassette is operable in one or both of a tissue sample collection mode and a bypass mode.

Abstract: A personal protection system including a garment configured for attachment to a helmet, wherein the garment defines a barrier between a wearer and an environment. The system includes a control mount integral to the garment and at least partially disposed on the environment side and the wearer side of the barrier. The system may include an emitter and a sensor configured to detect a signal output by the emitter. The control mount may comprise a lens configured to transmit the signal from the emitter through the garment. A control member may be coupled to the control mount and configured to be manipulated by the wearer. When manipulated by the wearer, the control member may distort and/or disrupt the transfer of the signal through the lens that is detected by the sensor. The sensor may provide a sensor input signal based on the signal detected from the emitter.

Abstract: A manifold apparatus and method of opening a valve in a medical/surgical waste collection unit. The manifold includes a base at a proximal end with the base defining an opening off center from an axis of the manifold. The manifold further includes two arcuately spaced tabs, each subtending arcs having different arcuate lengths. The manifold is positioned such that the tabs mate with at least two slots of a lock ring of the waste collection unit so as to cause the opening of the manifold to be, upon insertion into a bore of the waste collection unit, in a specific rotational alignment in the bore. The manifold is rotated within the bore to cause a valve disk to move between a first position in which the valve disk blocks fluid flow through the receiver and a second position in which the valve disk allows fluid flow through the receiver.

Abstract: A person protection system including a garment configured for attachment to a helmet, wherein the garment defines a barrier between the wearer and the environment. The system includes a control mount integral to the garment and at least partially disposed on an environment side and a wearer side of the barrier. The control mount may include a lens configured to transfer light through the garment, and a sensor configured to detect the light transferred or reflected through the lens. A control member may be coupled to the control mount and configured to be manipulated by the wearer. When manipulated by the wearer, the control member may distort and/or disrupt the transfer of light through the lens that is detected by the sensor. The sensor may provide a sensor input signal based on the detected light.

Abstract: A person protection system including a garment configured for attachment to a helmet, wherein the garment defines a barrier between the wearer and the environment. The system includes a control mount integral to the garment and at least partially disposed on an environment side and a wearer side of the barrier. The control mount may include a lens configured to transfer light through the garment, and a sensor configured to detect the light transferred or reflected through the lens. A control member may be coupled to the control mount and configured to be manipulated by the wearer. When manipulated by the wearer, the control member may distort and/or disrupt the transfer of light through the lens that is detected by the sensor. The sensor may provide a sensor input signal based on the detected light.

Abstract: A removable manifold for a medical/surgical waste collection system. The manifold is dimensioned to be mounted to a receiver integral with the system. The manifold includes a includes at least one fitting through which waste is drawn into the manifold. The fitting opens through an inlet port into a void space internal to the manifold. The manifold includes a drip stop.

Abstract: A specimen collection cassette for a medical fluid collection system. A housing defines a first void space and a second void space, and an outlet opening in fluid communication with the first and second void spaces. An aperture may be within a wall separating the first and second void spaces with the aperture providing fluid communication between the first and second void spaces. First and second fittings receive a suction line for drawing fluid into the first and second void spaces, respectively. A fluid communication path is established from the first fitting to the outlet opening through the first void space, aperture, and the second void space, and a bypass fluid communication path is established from the second bore to the outlet opening through the second void space. The cassette is operable in one or both of a tissue sample collection mode and a bypass mode.

Abstract: A cassette (2600) for use with a medical waste collection system (30). The cassette includes a housing (2602, 2612) shaped to be removably attached to a receptacle (1699) integral with the housing. A sleeve (2640) is attached to the cassette so as to be located forward of the housing. The sleeve is formed with a void space. A fitting (2664) for collection to a suction line is attached to the sleeve. A screen (2714) is removably fitted in the sleeve void space. The screen is fitted in the sleeve void space when it is desirable to catch tissue that may be entrained in the fluid stream from the suction line.

Abstract: A surgical waste collection unit with a receiver for removably holding a manifold to which suction lines are connected. The receiver is mounted to the waste collection unit to be at an acute angle relative to the horizontal. The receiver is further configured to allow the manifold to be rotated in the receiver. This means the manifold can be rotated from a first position in which the manifold outlet opening is aligned with the conduit through which waste is flowed from the receiver and a second position in which the manifold outlet opening is elevated relative to the first position.

Abstract: A surgical waste collection unit with a receiver for removably holding a manifold to which suction lines are connected. The receiver is mounted to the waste collection unit to be at an acute angle relative to the horizontal. The receiver is further configured to allow the manifold to be rotated in the receiver. This means the manifold can be rotated from a first position in which the manifold outlet opening is aligned with the conduit through which waste is flowed from the receiver and a second position in which the manifold outlet opening is elevated relative to the first position.

Abstract: A manifold for use with a surgical waste collection unit. The manifold includes a housing dimensioned to seat in a receiver of the waste collection unit with a fitting for receiving a suction tube. The housing has an outlet opening through which a suction is drawn so as to draw waste through the suction line, the fitting and the housing into the waste collection unit. Two tabs extends radially outwardly from the housing. The tabs are dimensioned to engage complementary slots in the receiver so as to facilitate the rotation alignment of the manifold in the receiver. In many versions of the invention, the tabs subtend different arcuate lengths. A filter is disposed in the housing to filter material that, as a consequence of the suction being drawn on the housing, is drawn through the housing.

Abstract: A surgical waste collection unit with a receiver for removably holding a manifold to which suction lines are connected. The receiver is mounted to the waste collection unit to be at an acute angle relative to the horizontal. The receiver is further configured to allow the manifold to be rotated in the receiver. This means the manifold can be rotated from a first position in which the manifold outlet opening is aligned with the conduit through which waste is flowed from the receiver and a second position in which the manifold outlet opening is elevated relative to the first position.