Patents by Inventor Stephen Roman

Stephen Roman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12616707
    Abstract: Various embodiments of a gut microbiome modulating composition comprises a blend of a polyphenol and an oligosaccharide. Various embodiments of the polyphenol may comprise at least approximately 5% by weight chlorogenic acid. Various embodiments of the oligosaccharides may be standardized to a degree of polymerization of at least three to reduce digestibility. Administration of an effective amount of the gut microbiome modulating composition to a person or animal may stimulate the growth of at least one of Akkermansia muciniphila, Lactobacillus, and Bifidobacterium bacteria in the colon, which may reduce permeability of the colon, increases short chain fatty acid production in the colon, and/or modulate causes immunomodulation of human colon cells. The gut microbiome modulating composition may provide protective effects against obesity-related chronic diseases.
    Type: Grant
    Filed: May 26, 2023
    Date of Patent: May 5, 2026
    Assignee: Plexus Worldwide, LLC
    Inventors: Stephen Roman, Tianan Jiang, Marco Rebaza
  • Publication number: 20230302029
    Abstract: Various embodiments of a gut microbiome modulating composition comprises a blend of a polyphenol and an oligosaccharide. Various embodiments of the polyphenol may comprise at least approximately 5% by weight chlorogenic acid. Various embodiments of the oligosaccharides may be standardized to a degree of polymerization of at least three to reduce digestibility. Administration of an effective amount of the gut microbiome modulating composition to a person or animal may stimulate the growth of at least one of Akkermansia muciniphila, Lactobacillus, and Bifidobacterium bacteria in the colon, which may reduce permeability of the colon, increases short chain fatty acid production in the colon, and/or modulate causes immunomodulation of human colon cells. The gut microbiome modulating composition may provide protective effects against obesity-related chronic diseases.
    Type: Application
    Filed: May 26, 2023
    Publication date: September 28, 2023
    Applicant: Plexus Worldwide, LLC.
    Inventors: Stephen Roman, Tianan Jiang, Marco Rebaza
  • Patent number: 11730749
    Abstract: Various embodiments of a gut microbiome modulating composition comprises a blend of a polyphenol and an oligosaccharide. Various embodiments of the polyphenol may comprise at least approximately 5% by weight chlorogenic acid. Various embodiments of the oligosaccharides may be standardized to a degree of polymerization of at least three to reduce digestibility. Administration of an effective amount of the gut microbiome modulating composition to a person or animal may stimulate the growth of at least one of Akkermansia muciniphila, Lactobacillus, and Bifidobacterium bacteria in the colon, which may reduce permeability of the colon, increases short chain fatty acid production in the colon, and/or modulate causes immunomodulation of human colon cells. The gut microbiome modulating composition may provide protective effects against obesity-related chronic diseases.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: August 22, 2023
    Assignee: Plexus Worldwide, LLC
    Inventors: Stephen Roman, Tianan Jiang, Marco Rebaza
  • Publication number: 20230060688
    Abstract: Various embodiments provide topical compositions and methods for treating the skin to modulate the skin microbiome. The application of various embodiments of the topical composition may modulate the growth of various commensal bacterial in the skin microbiome when applied to the skin, which may improve the immune function of the skin and/or reduce premature aging of the skin.
    Type: Application
    Filed: October 31, 2022
    Publication date: March 2, 2023
    Applicant: Plexus Worldwide, LLC
    Inventors: Tianan Jiang, Cynthia Latham, Stephen Roman, Randa Nabaty, Christin Powell
  • Publication number: 20210069088
    Abstract: Various embodiments provide topical compositions and methods for treating the skin to modulate the skin microbiome. The application of various embodiments of the topical composition may modulate the growth of various commensal bacterial in the skin microbiome when applied to the skin, which may improve the immune function of the skin and/or reduce premature aging of the skin.
    Type: Application
    Filed: March 8, 2019
    Publication date: March 11, 2021
    Applicant: Plexus Worldwide, LLC.
    Inventors: Tianan Jiang, Cynthia Latham, Stephen Roman, Randa Nabaty, Christin Powell
  • Publication number: 20180318323
    Abstract: Various embodiments of a gut microbiome modulating composition comprises a blend of a polyphenol and an oligosaccharide. Various embodiments of the polyphenol may comprise at least approximately 5% by weight chlorogenic acid. Various embodiments of the oligosaccharides may be standardized to a degree of polymerization of at least three to reduce digestibility. Administration of an effective amount of the gut microbiome modulating composition to a person or animal may stimulate the growth of at least one of Akkermansia muciniphila, Lactobacillus, and Bifidobacterium bacteria in the colon, which may reduce permeability of the colon, increases short chain fatty acid production in the colon, and/or modulate causes immunomodulation of human colon cells. The gut microbiome modulating composition may provide protective effects against obesity-related chronic diseases.
    Type: Application
    Filed: May 7, 2018
    Publication date: November 8, 2018
    Inventors: Stephen Roman, Tianan Jiang, Marco Rebaza
  • Publication number: 20070134280
    Abstract: A thixotropic formulation includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.
    Type: Application
    Filed: February 9, 2007
    Publication date: June 14, 2007
    Inventors: Stephen Roman, Gary Kehoe
  • Publication number: 20070135377
    Abstract: A thixotropic anti-viral formulation includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.
    Type: Application
    Filed: February 9, 2007
    Publication date: June 14, 2007
    Inventors: Stephen Roman, Gary Kehoe
  • Publication number: 20060292102
    Abstract: A thixotropic personal lubricant includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.
    Type: Application
    Filed: August 9, 2006
    Publication date: December 28, 2006
    Inventors: Stephen Roman, Gary Kehoe
  • Publication number: 20060211994
    Abstract: An IV holder for securing an IV needle and Luer fitting assembly. The IV holder includes a frame defining an aperture with a first portion and a second portion, the first portion of the aperture further being covered by a transparent window for protecting and securing the IV needle insertion site. The second portion of the aperture is disposed to fit a cylindrical Luer fitting. The holder is adhesively applied to a patient's skin and situated so that the needle insertion site is under the window and the first portion of the aperture while the Luer fitting is disposed within the second portion of the aperture.
    Type: Application
    Filed: December 22, 2005
    Publication date: September 21, 2006
    Inventors: Stephen Roman, Gary Kehoe
  • Publication number: 20060127340
    Abstract: A thixotropic personal lubricant includes a high molecular weight, thixotropic, gel-forming, naturally occurring polysaccharide extracted from algae and comprised of repeating sulfated and non-sulfated galactose and 3,6 anhydrogalactose (3,6-AG) units, and includes water.
    Type: Application
    Filed: August 24, 2005
    Publication date: June 15, 2006
    Inventors: Stephen Roman, Gary Kehoe