Patents by Inventor Stephen Rothenburger
Stephen Rothenburger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9597072Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.Type: GrantFiled: April 17, 2012Date of Patent: March 21, 2017Assignee: Ethicon, Inc.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Patent number: 9149273Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.Type: GrantFiled: March 13, 2013Date of Patent: October 6, 2015Assignee: Ethicon, Inc.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Patent number: 8668867Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.Type: GrantFiled: March 13, 2012Date of Patent: March 11, 2014Assignee: Ethicon, Inc.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Publication number: 20120227360Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.Type: ApplicationFiled: March 13, 2012Publication date: September 13, 2012Applicant: ETHICON, INC.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Publication number: 20120199502Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.Type: ApplicationFiled: April 17, 2012Publication date: August 9, 2012Applicant: ETHICON, INC.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Patent number: 8156718Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.Type: GrantFiled: April 2, 2009Date of Patent: April 17, 2012Assignee: Ethicon, Inc.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Patent number: 8133437Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.Type: GrantFiled: December 13, 2005Date of Patent: March 13, 2012Assignee: Ethicon, Inc.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Publication number: 20110076312Abstract: An antimicrobial composition for coating a medical device. The antimicrobial composition includes a polymeric film forming material and an antimicrobial agent comprising a material selected from the group of extract of Houttuynia cordata, sodium houttuyfonate, sodium new houttuyfonate and mixtures thereof. A medical device having an antimicrobial composition that includes a material selected from the group of extract of Houttuynia cordata, sodium houttuyfonate, sodium new houttuyfonate and mixtures thereof and a method for making same are also provided.Type: ApplicationFiled: September 29, 2009Publication date: March 31, 2011Applicant: ETHICON, INC.Inventors: Henry Pokropinski, JR., Jerome A. Fischer, Jerry Jonn, Huimin Wang, Stephen Rothenburger, Xintian Ming
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Publication number: 20090301033Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.Type: ApplicationFiled: April 2, 2009Publication date: December 10, 2009Applicant: ETHICON, INC.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Patent number: 7513093Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.Type: GrantFiled: December 13, 2005Date of Patent: April 7, 2009Assignee: Ethicon, Inc.Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
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Publication number: 20070292469Abstract: A stabilized antimicrobial composition comprising (a) polymeric polyquaternary ammonium compounds and (b) an antimicrobial metal, such as elemental silver, alloys thereof or silver compounds. The antimicrobial composition may be used as a stand-alone composition, in an antimicrobial formulation, or in combination with medical articles or medical devices. The antimicrobial composition prevents silver-containing formulations and medical devices from discoloration and loss of antimicrobial activity.Type: ApplicationFiled: July 25, 2005Publication date: December 20, 2007Inventors: Stephen Rothenburger, Xintian Ming
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Publication number: 20070225220Abstract: An antimicrobial composition comprising (a) a cationic surfactant derived from the condensation of fatty acids and esterified dibasic amino acids, such as lauric arginate and (b) an antibiotic, such as of ?-lactam antibiotics, polypeptides, quinolones. The composition may be used as a stand alone antimicrobial formulation, or in combination with medical articles or medical devices.Type: ApplicationFiled: March 27, 2006Publication date: September 27, 2007Inventors: Xintian Ming, Stephen Rothenburger
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Publication number: 20060263444Abstract: An antimicrobial composition comprising (a) a cationic surfactant derived from the condensation of fatty acids and esterified dibasic amino acids, such as lauric arginate, and (b) an antimicrobial metal, such as elemental silver or alloys thereof or silver compounds. The composition may be used as a stand alone antimicrobial formulation, or in combination with medical articles or medical devices.Type: ApplicationFiled: May 19, 2005Publication date: November 23, 2006Inventors: Xintian Ming, Stephen Rothenburger
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Publication number: 20060264347Abstract: An antimicrobial composition comprising (a) a cationic surfactant derived from the condensation of fatty acids and esterified dibasic amino acids, such as lauric arginate, and (b) an iodinated sulfone compound such as diiodomethyl-p-tolylsulfone. The composition may be used as a stand-alone antimicrobial formulation, or in combination with medical articles or medical devices.Type: ApplicationFiled: May 19, 2005Publication date: November 23, 2006Inventors: Xintian Ming, Stephen Rothenburger
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Publication number: 20060091035Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.Type: ApplicationFiled: December 13, 2005Publication date: May 4, 2006Inventors: Howard Scalzo, Jerome Fischer, Stephen Rothenburger, Robert Cerwin, James McDivitt
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Publication number: 20060091034Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.Type: ApplicationFiled: December 13, 2005Publication date: May 4, 2006Inventors: Howard Scalzo, Jerome Fischer, Stephen Rothenburger, Robert Cerwin, James McDivitt
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Publication number: 20040220614Abstract: An antimicrobial suture assembly comprising a containment compartment comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on said containment compartment; and a suture positioned within the containment compartment, the suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, and at least one active agent selected from the group consisting of a biocide, a disinfectant, an antiseptic, an antibiotic, an antimicrobial peptide, a lytic bacteriophage, a surfactant; an adhesion blocker; an oligonucleotide, an efflux pump inhibitors; a photosensitive dye, an immune modulator and a chelator.Type: ApplicationFiled: March 25, 2004Publication date: November 4, 2004Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger
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Publication number: 20040068293Abstract: An antimicrobial suture assembly comprising a containment compartment comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on said containment compartment; and a suture positioned within the containment compartment, the suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on the suture; and a method for making.Type: ApplicationFiled: February 15, 2003Publication date: April 8, 2004Inventors: Howard Scalzo, Jerome A. Fischer, James R. McDivitt, Stephen Rothenburger, Robert Cerwin