Patents by Inventor Stephen Rothenburger

Stephen Rothenburger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9597072
    Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: March 21, 2017
    Assignee: Ethicon, Inc.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Patent number: 9149273
    Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: October 6, 2015
    Assignee: Ethicon, Inc.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Patent number: 8668867
    Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: March 11, 2014
    Assignee: Ethicon, Inc.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Publication number: 20120227360
    Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.
    Type: Application
    Filed: March 13, 2012
    Publication date: September 13, 2012
    Applicant: ETHICON, INC.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Publication number: 20120199502
    Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
    Type: Application
    Filed: April 17, 2012
    Publication date: August 9, 2012
    Applicant: ETHICON, INC.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Patent number: 8156718
    Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: April 17, 2012
    Assignee: Ethicon, Inc.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Patent number: 8133437
    Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: March 13, 2012
    Assignee: Ethicon, Inc.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Publication number: 20110076312
    Abstract: An antimicrobial composition for coating a medical device. The antimicrobial composition includes a polymeric film forming material and an antimicrobial agent comprising a material selected from the group of extract of Houttuynia cordata, sodium houttuyfonate, sodium new houttuyfonate and mixtures thereof. A medical device having an antimicrobial composition that includes a material selected from the group of extract of Houttuynia cordata, sodium houttuyfonate, sodium new houttuyfonate and mixtures thereof and a method for making same are also provided.
    Type: Application
    Filed: September 29, 2009
    Publication date: March 31, 2011
    Applicant: ETHICON, INC.
    Inventors: Henry Pokropinski, JR., Jerome A. Fischer, Jerry Jonn, Huimin Wang, Stephen Rothenburger, Xintian Ming
  • Publication number: 20090301033
    Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
    Type: Application
    Filed: April 2, 2009
    Publication date: December 10, 2009
    Applicant: ETHICON, INC.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Patent number: 7513093
    Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: April 7, 2009
    Assignee: Ethicon, Inc.
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger, Robert Cerwin, James R. McDivitt
  • Publication number: 20070292469
    Abstract: A stabilized antimicrobial composition comprising (a) polymeric polyquaternary ammonium compounds and (b) an antimicrobial metal, such as elemental silver, alloys thereof or silver compounds. The antimicrobial composition may be used as a stand-alone composition, in an antimicrobial formulation, or in combination with medical articles or medical devices. The antimicrobial composition prevents silver-containing formulations and medical devices from discoloration and loss of antimicrobial activity.
    Type: Application
    Filed: July 25, 2005
    Publication date: December 20, 2007
    Inventors: Stephen Rothenburger, Xintian Ming
  • Publication number: 20070225220
    Abstract: An antimicrobial composition comprising (a) a cationic surfactant derived from the condensation of fatty acids and esterified dibasic amino acids, such as lauric arginate and (b) an antibiotic, such as of ?-lactam antibiotics, polypeptides, quinolones. The composition may be used as a stand alone antimicrobial formulation, or in combination with medical articles or medical devices.
    Type: Application
    Filed: March 27, 2006
    Publication date: September 27, 2007
    Inventors: Xintian Ming, Stephen Rothenburger
  • Publication number: 20060263444
    Abstract: An antimicrobial composition comprising (a) a cationic surfactant derived from the condensation of fatty acids and esterified dibasic amino acids, such as lauric arginate, and (b) an antimicrobial metal, such as elemental silver or alloys thereof or silver compounds. The composition may be used as a stand alone antimicrobial formulation, or in combination with medical articles or medical devices.
    Type: Application
    Filed: May 19, 2005
    Publication date: November 23, 2006
    Inventors: Xintian Ming, Stephen Rothenburger
  • Publication number: 20060264347
    Abstract: An antimicrobial composition comprising (a) a cationic surfactant derived from the condensation of fatty acids and esterified dibasic amino acids, such as lauric arginate, and (b) an iodinated sulfone compound such as diiodomethyl-p-tolylsulfone. The composition may be used as a stand-alone antimicrobial formulation, or in combination with medical articles or medical devices.
    Type: Application
    Filed: May 19, 2005
    Publication date: November 23, 2006
    Inventors: Xintian Ming, Stephen Rothenburger
  • Publication number: 20060091035
    Abstract: A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.
    Type: Application
    Filed: December 13, 2005
    Publication date: May 4, 2006
    Inventors: Howard Scalzo, Jerome Fischer, Stephen Rothenburger, Robert Cerwin, James McDivitt
  • Publication number: 20060091034
    Abstract: A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.
    Type: Application
    Filed: December 13, 2005
    Publication date: May 4, 2006
    Inventors: Howard Scalzo, Jerome Fischer, Stephen Rothenburger, Robert Cerwin, James McDivitt
  • Publication number: 20040220614
    Abstract: An antimicrobial suture assembly comprising a containment compartment comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on said containment compartment; and a suture positioned within the containment compartment, the suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, and at least one active agent selected from the group consisting of a biocide, a disinfectant, an antiseptic, an antibiotic, an antimicrobial peptide, a lytic bacteriophage, a surfactant; an adhesion blocker; an oligonucleotide, an efflux pump inhibitors; a photosensitive dye, an immune modulator and a chelator.
    Type: Application
    Filed: March 25, 2004
    Publication date: November 4, 2004
    Inventors: Howard Scalzo, Jerome A. Fischer, Stephen Rothenburger
  • Publication number: 20040068293
    Abstract: An antimicrobial suture assembly comprising a containment compartment comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on said containment compartment; and a suture positioned within the containment compartment, the suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on the suture; and a method for making.
    Type: Application
    Filed: February 15, 2003
    Publication date: April 8, 2004
    Inventors: Howard Scalzo, Jerome A. Fischer, James R. McDivitt, Stephen Rothenburger, Robert Cerwin