Patents by Inventor Stephen Rubin

Stephen Rubin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150283139
    Abstract: Disclosed herein is a method of treating breast cancer that has metastasized to the brain in a mammal by administration of 4-quinazolinamines and pharmaceutical compositions containing the same. In particular, the method relates to methods of treating breast cancer brain metastases which overexpress erbB2 by administration of N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine and salts and solvates thereof.
    Type: Application
    Filed: April 20, 2015
    Publication date: October 8, 2015
    Inventor: Stephen Rubin
  • Patent number: 7910570
    Abstract: The invention relates to a method of treating endometriosis using a combination of an aromatase inhibitor, a progestin and an oestrogen. The invention also relates to pharmaceutical formulations comprising said combination.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: March 22, 2011
    Assignee: AstraZeneca AB
    Inventors: Stephen Rubin, Serdar E. Bulun
  • Publication number: 20110009373
    Abstract: The invention relates to a method of treating endometriosis using a combination of an aromatase inhibitor, a progestin and an oestrogen. The invention also relates to pharmaceutical formulations comprising said combination.
    Type: Application
    Filed: September 20, 2010
    Publication date: January 13, 2011
    Applicant: ASTRAZENECA AB
    Inventor: Stephen Rubin
  • Publication number: 20080306097
    Abstract: Disclosed herein is a method of treating breast cancer that has metastasized to the brain in a mammal by administration of 4-quinazolinamines and pharmaceutical compositions containing the same. In particular, the method relates to methods of treating breast cancer brain metastases which overexpress erbB2 by administration of N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine and salts and solvates thereof.
    Type: Application
    Filed: December 16, 2005
    Publication date: December 11, 2008
    Applicant: SMITHKLINE BEECHAM (CORK) LIMITED
    Inventor: Stephen Rubin
  • Publication number: 20060142256
    Abstract: The invention relates to a method of treating endometriosis using a combination of an aromatase inhibitor, a progestin and an oestrogen. The invention also relates to pharmaceutical formulations comprising said combination.
    Type: Application
    Filed: February 3, 2004
    Publication date: June 29, 2006
    Inventor: Stephen Rubin