Patents by Inventor Stephen Ruble
Stephen Ruble has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10603020Abstract: A medical device for reducing the volume of a left atrial appendage (LAA) may include an elongate shaft having a distal portion, and a volume-reducing means expandable from a collapsed to an expanded state, the volume-reducing means being releasably attached to the distal portion. The volume-reducing means may include an actuatable frame and an impermeable covering disposed over the frame. The volume-reducing means may be sized to fit within the LAA in the expanded state while maintaining an open fluid flow path from a distal region through the ostium of the LAA. A medical device may include a second volume-reducing means to be placed within and substantially occlude a distalmost region of the LAA. A method may include inserting a volume-reducing means into the LAA, expanding the volume-reducing means, and positioning the volume-reducing means such that an open fluid flow path is maintained through an entire cycle of the heart.Type: GrantFiled: November 22, 2016Date of Patent: March 31, 2020Assignee: Boston Scientific Sciemed, Inc.Inventors: Barry Rudman, Jan Weber, Torsten Scheuermann, Stephen Ruble
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Patent number: 9855431Abstract: Various device embodiments may comprise an implantable medical device for implantation in a body and for applying neural stimulation to a neural target in the body. The device may comprise a neural stimulation electrode configured for use in stimulating the neural target, a neural stimulator configured to deliver neural stimulation through the electrode to the neural target, a sensor configured to sense a physiological response to stimulation of motor fibers at the neural target, and a controller operatively connected to the neural stimulator to control the neural stimulation and operatively connected to the sensor to receive a signal indicative of the physiological response. The controller may be configured to detect a potential neural injury and perform an action in response to the detected potential neural injury.Type: GrantFiled: February 20, 2013Date of Patent: January 2, 2018Assignee: Cardiac Pacemakers, Inc.Inventors: David J. Ternes, Jason J. Hamann, Stephen Ruble
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Publication number: 20170095238Abstract: A medical device for reducing the volume of a left atrial appendage (LAA) may include an elongate shaft having a distal portion, and a volume-reducing means expandable from a collapsed to an expanded state, the volume-reducing means being releasably attached to the distal portion. The volume-reducing means may include an actuatable frame and an impermeable covering disposed over the frame. The volume-reducing means may be sized to fit within the LAA in the expanded state while maintaining an open fluid flow path from a distal region through the ostium of the LAA. A medical device may include a second volume-reducing means to be placed within and substantially occlude a distalmost region of the LAA. A method may include inserting a volume-reducing means into the LAA, expanding the volume-reducing means, and positioning the volume-reducing means such that an open fluid flow path is maintained through an entire cycle of the heart.Type: ApplicationFiled: November 22, 2016Publication date: April 6, 2017Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Barry Rudman, Jan Weber, Torsten Scheuermann, Stephen Ruble
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Patent number: 9526893Abstract: A first fluid status indicator of a pulmonary fluid status associated with pulmonary edema and a second fluid status indicator of a non-pulmonary fluid status can be used to provide an alert or to control a therapy for pulmonary edema. Additionally, intermittent cardiac blood volume redistribution therapy can be used to provide cardiac conditioning in heart failure patients.Type: GrantFiled: June 25, 2013Date of Patent: December 27, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: Viktoria A. Averina, Jason J. Hamann, Stephen Ruble, Allan C. Shuros
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Patent number: 9314627Abstract: Some embodiments provide a method, comprising performing a neural stimulation test routine for stimulating a neural target in a cervical region of a patient, wherein for each of a plurality of head positions, performing the neural stimulation test routine includes testing a plurality of electrode configurations. The method further comprises recording threshold data for each of the tested electrode configurations for the plurality of head positions, and recommending an electrode configuration based on the recorded threshold data.Type: GrantFiled: April 23, 2012Date of Patent: April 19, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: Shantha Arcot-Krishnamurthy, Stephen Ruble, Jason J. Hamann, Juan Gabriel Hincapie Ordonez, David J. Ternes
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Patent number: 9265431Abstract: A neurostimulation system provides for capture verification and stimulation intensity adjustment to ensure effectiveness of vagus nerve stimulation in modulating one or more target functions in a patient. In various embodiments, stimulation is applied to the vagus nerve, and evoked responses are detected to verify that the stimulation captures the vagus nerve and to adjust one or more stimulation parameters that control the stimulation intensity.Type: GrantFiled: June 9, 2011Date of Patent: February 23, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: Juan Gabriel Hincapie Ordonez, David J. Ternes, Jason J. Hamann, Stephen Ruble
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Patent number: 9259575Abstract: Various system embodiments comprise an implantable lead, an implantable housing, a neural stimulation circuit in the housing, and a controller in the housing and connected to the neural stimulation circuit. The lead has a proximal end and a distal end. The distal end is adapted to deliver neural stimulation pulses to the ventral nerve root and the dorsal nerve root. The proximal end of the lead is adapted to connect to the housing. The neural stimulation circuit is adapted to generate neural stimulation pulses to stimulate the ventral nerve root or the dorsal nerve root using the implantable lead. The controller is adapted to control the neural stimulation circuit to deliver a neural stimulation treatment.Type: GrantFiled: January 10, 2013Date of Patent: February 16, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: Weiying Zhao, Stephen Ruble, Allan C. Shuros, Jason J. Hamann
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Patent number: 9259568Abstract: Various system embodiments comprise a lead having a distal end and a proximal end. The distal end includes a plurality of electrodes. The lead is configured to be fed into a dorsal epidural space of a human to a desired region of a spinal column and to be fed laterally to at least partially encircle a spinal cord in the desired region to place at least one stimulation electrode in position to stimulate a dorsal nerve root and at least another stimulation electrode in position to stimulate a ventral nerve root. The desired region may include cervical vertebrae, thoracic vertebrae, or lumbar vertebrae. Some embodiments stimulate the spinal cord in the T1-T5 region.Type: GrantFiled: April 28, 2009Date of Patent: February 16, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: Weiying Zhao, Stephen Ruble, Allan C. Shuros, Jason J. Hamann
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Patent number: 9242104Abstract: Various embodiments provide a method performed by an IMD to deliver a therapy to a patient. In some embodiments of the method, the therapy is delivered to the patient, and a trigger that is controlled by the patient is detected by the IMD. The therapy is automatically interrupted in response to the detected trigger, and is automatically restored after a defined period after the detected trigger. In some embodiments of the method, a trigger that is controlled by the patient is detected. The therapy is automatically initiated in response to the detected trigger, and is automatically stopped after a defined period after the detected trigger.Type: GrantFiled: May 10, 2011Date of Patent: January 26, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: Jason J. Hamann, Stephen Ruble, Rafael Carbunaru, David J. Ternes
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Patent number: 9227068Abstract: Various method embodiments detect a concurrent therapy, where the concurrent therapy includes a plurality of therapy pulses. Detecting the concurrent therapy includes detecting at least one electrical pulse, extracting at least one characteristic from the at least one electrical pulse, comparing the at least one characteristic of the detected pulse to at least one characteristic of therapy pulses, and detecting that the concurrent therapy is being applied if the at least one characteristic of the detected pulse favorably compares to the at least one characteristic of the therapy pulses.Type: GrantFiled: August 29, 2013Date of Patent: January 5, 2016Assignee: Cardiac Pacemakers, Inc.Inventors: David J. Ternes, Stephen Ruble, Jason J. Hamann, Kenneth L. Baker
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Patent number: 9126045Abstract: A neurostimulation system measures a cardiac parameter at various cardiac intervals and analyzes its restitution, including computing a restitution slope being a rate of change of the restitution parameter with respect to change in the cardiac interval. In various embodiments, the system uses the restitution slope to provide for adaptive control of neurostimulation. In various embodiments, one or more cardiac parameters such as action potential duration (APD), conduction velocity (CV), QT interval (QT), and/or T-wave morphology (TM) parameter are measured and analyzed for restitution of each parameter, which is then used to control the delivery of the neurostimulation.Type: GrantFiled: August 15, 2012Date of Patent: September 8, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Shibaji Shome, Stephen Ruble, Jason J. Hamann, Stephen J. Hahn, Arjun D. Sharma
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Patent number: 9089267Abstract: A neurostimulation system provides for capture verification and stimulation intensity adjustment to ensure effectiveness of vagus nerve stimulation in modulating one or more target functions in a patient. In various embodiments, stimulation is applied to the vagus nerve, and evoked responses are detected to verify that the stimulation captures the vagus nerve and to adjust one or more stimulation parameters that control the stimulation intensity.Type: GrantFiled: June 9, 2011Date of Patent: July 28, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Juan Gabriel Hincapie Ordonez, David J. Ternes, Jason J. Hamann, Stephen Ruble
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Patent number: 9002448Abstract: Various aspects provide an implantable device. In various embodiments, the device comprises at least one port, where each port is adapted to connect a lead with an electrode to the device. The device further includes a stimulation platform, including a sensing circuit connected to the at least one port to sense an intrinsic cardiac signal and a stimulation circuit connected to the at least one port via a stimulation channel to deliver a stimulation signal through the stimulation channel to the electrode. The stimulation circuit is adapted to deliver stimulation signals through the stimulation channel for both neural stimulation therapy and CRM therapy. The sensing and stimulation circuits are adapted to perform CRM functions. The device further includes a controller connected to the sensing circuit and the stimulation circuit to control the neural stimulation therapy and the CRM therapy. Other aspects and embodiments are provided herein.Type: GrantFiled: June 3, 2013Date of Patent: April 7, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Imad Libbus, Andrew P. Kramer, Anthony V. Caparso, Kristofer J. James, Stephen Ruble, Weiying Zhao
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Patent number: 8983617Abstract: A neurostimulation system senses a signal indicative of a patient's physical state such as posture and/or activity level. In various embodiments, a stored value for each of stimulation parameters controlling delivery of neurostimulation is selected according to the patient's physical state. In various embodiments, values of the stimulation parameters are approximately optimized for each of a number of different physical states, and are stored for later selection.Type: GrantFiled: April 8, 2013Date of Patent: March 17, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Abhi V. Chavan, Keith R. Maile, David J. Ternes, Juan Gabriel Hincapie Ordonez, Stephen Ruble, Jason J. Hamann
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Patent number: 8972022Abstract: A neurostimulation system provides for capture verification and stimulation intensity adjustment to ensure effectiveness of vagus nerve stimulation in modulating one or more target functions in a patient. In various embodiments, stimulation is applied to the vagus nerve, and evoked responses are detected to verify that the stimulation captures the vagus nerve and to adjust one or more stimulation parameters that control the stimulation intensity.Type: GrantFiled: June 9, 2011Date of Patent: March 3, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Juan Gabriel Hincapie Ordonez, David J. Ternes, Jason J. Hamann, Stephen Ruble
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Patent number: 8954167Abstract: A lead assembly for an implantable medical device includes a lead body having a proximal end and a distal end. One or more connectors at the proximal end of the lead body are each adapted for connection to a pulse generator. One or more conductive elements are coupled to the one or more connectors at the proximal end and extend through the lead body to the distal end. Each of the one or more conductive elements includes an electrode coil that extends from the distal end of the lead body that is formed into a helix having a diameter greater than a diameter of the electrode coil.Type: GrantFiled: March 5, 2010Date of Patent: February 10, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Paul E. Zarembo, Stephen Ruble
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Patent number: 8942819Abstract: Various neural stimulator embodiments comprise controller circuitry, neural stimulation output circuitry, sensor circuitry and a memory. The neural stimulation output circuitry is configured to deliver the neural stimulation. The controller circuitry is configured to control stimulation parameters of the neural stimulation delivered by the neural stimulation output circuitry. The sensor circuitry, including at least one sensor, is configured to sense a response to the neural stimulation. The controller is configured to communicate with the sensor circuitry. The memory has instructions stored therein, operable on by the controller circuitry.Type: GrantFiled: June 8, 2011Date of Patent: January 27, 2015Assignee: Cardiac Pacemakers, Inc.Inventors: Juan Gabriel Hincapie Ordonez, Stephen Ruble, Jason J. Hamann, Eric A. Mokelke, Shantha Arcot-Krishnamurthy, Kevin John Stalsberg, David J. Ternes
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Patent number: 8855772Abstract: This document discusses, among other things, a system and method for calculating a neural stimulation energy at an external patient management (EPM) system using received information about a chemical characteristic indicative of a physiological state of a subject.Type: GrantFiled: November 12, 2008Date of Patent: October 7, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Allan C. Shuros, Craig Stolen, Timothy Meyer, Stephen Ruble
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Patent number: 8812130Abstract: An implantable apparatus can comprise an electrical test energy delivery circuit configured to provide an electrical test signal to a cervical location in a patient body. A detector circuit can use the electrical test signal to detect cervical impedance and generate a cervical impedance signal representing fluctuations in the detected cervical impedance. The implantable apparatus can comprise a therapy delivery circuit, such as configured to provide electrical neural modulation therapy using a neural modulation timing parameter, and a processor circuit that can be coupled to the electrical test energy delivery circuit, the detector circuit, and the therapy delivery circuit.Type: GrantFiled: February 7, 2013Date of Patent: August 19, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: Jeffrey E. Stahmann, Stephen Ruble, Jason J. Hamann, David J. Ternes
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Patent number: 8805502Abstract: An apparatus comprises a cardiac signal sensing circuit configured to sense an electrical cardiac signal from at least one of an atrium or ventricle of a heart of a subject, a therapy circuit configured to provide electrical pacing therapy and electrical neural stimulation therapy to the subject, and a control circuit. The control circuit is configured to initiate delivery of the electrical pacing therapy, initiate a blanking period in a time relationship to the delivery of electrical pacing therapy, and initiate delivery of the electrical neural stimulation therapy to the subject during the blanking period. At least one sense amplifier of the cardiac signal sensing circuit is disabled during the blanking period.Type: GrantFiled: December 5, 2012Date of Patent: August 12, 2014Assignee: Cardiac Pacemakers, Inc.Inventors: David J. Ternes, Stephen Ruble, Jeffrey E. Stahmann, Jason J. Hamann