Patents by Inventor Stephen Ryley

Stephen Ryley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS
    Publication number: 20080113993
    Abstract: This invention pertains to active barbituric acid analogs which inhibit HIF-1 activity (e.g., the interaction between HIF-1$g(a) and p300) and thereby inhibit angiogenesis, tumorigenesis, and proliferative conditions, such as cancer. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HIF-1 activity, and to inhibit angiogenesis, tumorigenesis, and proliferative conditions, such as cancer.
    Type: Application
    Filed: January 16, 2008
    Publication date: May 15, 2008
    Applicant: Via Ariosto, 23
    Inventors: Jackie DE BELIN, Maria-Rosario Romero-Martin, Paul Finn, Lee Sayers, Norman Law, David Billington, Stephen Ryley, Shoumo Bhattacharya
  • Barbituric acid analogs as therapeutic agents
    Publication number: 20030229108
    Abstract: This invention pertains to active barbituric acid analogs which inhibit HIF-1 activity (e.g., the interaction between HIF-1&agr; and p300) and thereby inhibit angiogenesis, tumorigensis, and proliferative conditions, such as cancer. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HIF-1 activity, and to inhibit angiogensis, tumorigensis, and proliferative conditions, such as cancer.
    Type: Application
    Filed: May 21, 2003
    Publication date: December 11, 2003
    Inventors: Jackie Y De Belin, Maria-Rosario Romero-Martin, Paul W Finn, Lee G Sayers, Norman M Law, David C Billington, Stephen Ryley, Shoumo Bhattacharya