Patents by Inventor Stephen Scully

Stephen Scully has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENGINEERED RETRONS AND METHODS OF USE
    Publication number: 20260062700
    Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g, mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
    Type: Application
    Filed: August 24, 2023
    Publication date: March 5, 2026
    Inventors: Alim LADHA, Vladimir PRESNYAK, Inna SHCHERBAKOVA, Brian GOODMAN, Mario Rodriguez MESTRE, Kyong-Rim KIEFFER-KWON, Socheata LY, Devin Scott QUINLAN, Muthusamy JAYARAMAN, Stephen SCULLY, Jacob LAYER, Abril Fleitas Beitans, Zhongxia YI
  • Acyclic lipids and methods of use thereof
    Patent number: 12545636
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Grant
    Filed: October 24, 2022
    Date of Patent: February 10, 2026
    Assignee: Renagade Therapeutics Management Inc.
    Inventors: Muthusamy Jayaraman, Stephen Scully
  • CONSTRAINED LIPIDS AND METHODS OF USE THEREOF
    Publication number: 20250313525
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Application
    Filed: December 9, 2024
    Publication date: October 9, 2025
    Inventors: Stephen Scully, Muthusamy Jayaraman, Ganapathy Subramanian Sankaran
  • CYCLIC LIPIDS AND METHODS OF USE THEREOF
    Publication number: 20250154102
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Application
    Filed: October 4, 2024
    Publication date: May 15, 2025
    Inventors: Muthusamy Jayaraman, Stephen Scully
  • ENGINEERED RETRONS AND METHODS OF USE
    Publication number: 20250154533
    Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
    Type: Application
    Filed: June 24, 2024
    Publication date: May 15, 2025
    Inventors: Alim Ladha, Vladimir Presnyak, Inna Shcherbakova, Brian Goodman, Mario Rodriguez Mestre, Devin Scott Quinlan, Muthusamy Jayaraman, Stephen Scully
  • Constrained lipids and methods of use thereof
    Patent number: 12215068
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Grant
    Filed: July 19, 2023
    Date of Patent: February 4, 2025
    Assignee: ReNAgade Therapeutics Management Inc.
    Inventors: Stephen Scully, Muthusamy Jayaraman, Ganapathy Subramanian Sankaran
  • Engineered retrons and methods of use
    Patent number: 12054739
    Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
    Type: Grant
    Filed: September 22, 2023
    Date of Patent: August 6, 2024
    Assignee: RENAGADE THERAPEUTICS MANAGEMENT INC.
    Inventors: Alim Ladha, Vladimir Presnyak, Inna Shcherbakova, Brian Goodman, Mario Rodriguez Mestre, Devin Scott Quinlan, Muthusamy Jayaraman, Stephen Scully
  • CYCLIC LIPIDS AND METHODS OF USE THEREOF
    Publication number: 20240182412
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Application
    Filed: June 15, 2023
    Publication date: June 6, 2024
    Inventors: Muthusamy Jayaraman, Stephen Scully
  • ENGINEERED RETRONS AND METHODS OF USE
    Publication number: 20240175058
    Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
    Type: Application
    Filed: September 22, 2023
    Publication date: May 30, 2024
    Inventors: Alim Ladha, Vladimir Presnyak, Inna Shcherbakova, Brian Goodman, Mario Rodriguez Mestre, Devin Scott Quinlan, Muthusamy Jayaraman, Stephen Scully
  • CONSTRAINED LIPIDS AND METHODS OF USE THEREOF
    Publication number: 20240067598
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Application
    Filed: July 19, 2023
    Publication date: February 29, 2024
    Inventors: Stephen Scully, Muthusamy Jayaraman, Ganapathy Subramanian Sankaran
  • Engineered retrons and methods of use
    Patent number: 11866728
    Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
    Type: Grant
    Filed: December 22, 2022
    Date of Patent: January 9, 2024
    Assignee: RENAGADE THERAPEUTICS MANAGEMENT INC.
    Inventors: Alim Ladha, Vladimir Presnyak, Inna Shcherbakova, Brian Goodman, Mario Rodriguez Mestre, Devin Scott Quinlan, Muthusamy Jayaraman, Stephen Scully
  • Cyclic lipids and methods of use thereof
    Patent number: 11773061
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Grant
    Filed: October 24, 2022
    Date of Patent: October 3, 2023
    Assignee: ReNAgade Therapeutics Management Inc.
    Inventors: Muthusamy Jayaraman, Stephen Scully
  • ENGINEERED RETRONS AND METHODS OF USE
    Publication number: 20230235365
    Abstract: Disclosed are engineered retrons and methods of use such as to modify the genome of a host (e.g., mammalian) cell by delivering the engineered retron or the encoded ncRNA in vitro or in vivo to the host (e.g., mammalian) cell.
    Type: Application
    Filed: December 22, 2022
    Publication date: July 27, 2023
    Applicant: ReNAgade Therapeutics Management Inc.
    Inventors: Alim Ladha, Vladimir Presnyak, Brian Goodman, Mario Rodriguez Mestre, Devin Scott Quinlan, Muthusamy Jayaraman, Stephen Scully
  • ACYCLIC LIPIDS AND METHODS OF USE THEREOF
    Publication number: 20230202966
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Application
    Filed: October 24, 2022
    Publication date: June 29, 2023
    Inventors: Muthusamy Jayaraman, Stephen Scully
  • CYCLIC LIPIDS AND METHODS OF USE THEREOF
    Publication number: 20230202977
    Abstract: The present disclosure details various lipids, compositions, and/or methods of optimized systems and delivery vehicles for the delivery of nucleic acid sequences, polypeptides or peptides for use in vaccinating against infectious agents.
    Type: Application
    Filed: October 24, 2022
    Publication date: June 29, 2023
    Inventors: Muthusamy Jayaraman, Stephen Scully