Patents by Inventor Stephen Sean Flack

Stephen Sean Flack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMICAL COMPOUNDS
    Publication number: 20110059043
    Abstract: The invention concerns benzodiazepine derivatives of Formula I: wherein W, X, L1, L2, L3, R1, R2, R3, R4, R5, R6 and R7 are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment or prophylaxis of hepatitis C virus infection.
    Type: Application
    Filed: September 2, 2010
    Publication date: March 10, 2011
    Applicant: ARROW THERAPEUTICS LIMITED
    Inventors: Michael Christopher Stratton BARNES, Helena Jade DENNISON, Stephen Sean FLACK, James Andrew LUMLEY, Pui Shan PANG, Keith Charles SPENCER
  • COMPOUNDS AND METHODS OF TREATMENT
    Publication number: 20110053934
    Abstract: A derivative, which is useful as a ret kinase inhibitor is described herein. The described invention also includes methods of using the same in the treatment of diseases mediated by inappropriate ret kinase activity.
    Type: Application
    Filed: January 21, 2010
    Publication date: March 3, 2011
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: RICHARD MARTYN ANGELL, IAN ROBERT BALDWIN, GEORGE STUART COCKERILL, STEPHEN SEAN FLACK, KAREN ELIZABETH LACKEY, PHILIP ALAN SKONE, KATHRYN JANE SMITH
  • 5-Acylamino-1,1?-biphenyl-4-carboxamide derivatives and their use as P38 kinase inhibitors
    Patent number: 7432289
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: October 7, 2008
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Suzanne Joy Merrick, Kathryn Jane Smith, Ann Louise Walker
  • Quinazoline Derivatives as Antiviral Agents
    Publication number: 20080114008
    Abstract: Compounds of formula (I) are found to be active in inhibiting replication of flaviviridac Formula (I) wherein: X represents a direct bond or a moiety -L-NR—, wherein R is hydrogen or C1-C4 alkyl, and L represents a C1-C4alkylene, C6-C10 aryl or 5- to 10-membered heteroaryl moiety; either R1 and R2, together with the N atom to which they are attached, form a 5- to 10-membered heterocyclyl group or a 5- to 10-membered heteroaryl group, or R1 represents hydrogen, C6-C10 aryl, C1-C4 alkyl or C1-C4 hydroxyalkyl and R2 represents C6-C10 aryl, C1-C4 alkyl or C1-C4 hydroxyalkyl; and R3 represents a C6-C10 aryl, C3-C6 carbocyclyl, 5- to 10-membered heteroaryl or 5- to 10-membered heterocyclyl moiety, said aryl, carbocyclyl, heteroaryl and heterocyclyl groups being unsubstituted or substituted by 1, 2 or 3 substituents selected from halogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 haloalkyl, C1-C4 haloalkoxy, hydroxy, thiol, —NH2, C1-C4 hydroxyalkyl, C1-C4 thioalkyl and C1-C4aminoalkyl substituents.
    Type: Application
    Filed: January 30, 2006
    Publication date: May 15, 2008
    Applicant: ARROW THERAPEUTICS LIMITED
    Inventors: George Stuart Cockerill, Stephen Sean Flack, Neil Mathews, James Iain Salter
  • Biphenylcarboxylic amide derivatives as p38 kinase inhibitors
    Patent number: 7309800
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: December 18, 2007
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker
  • Biphenyl-derivatives as p38-kinase inhibitors
    Patent number: 7183297
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: February 27, 2007
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker
  • Biphenylcarboxylic amide derivatives as p38-kinase inhibitors
    Patent number: 7151118
    Abstract: Compounds of formula (I): or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: December 19, 2006
    Assignee: Glaxo Group Limited
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Lainé, Ann Louise Walker
  • Biphenyl-derivatives as p38-kinase inhibitors
    Publication number: 20040249161
    Abstract: Compounds of formula (I), or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
    Type: Application
    Filed: April 15, 2004
    Publication date: December 9, 2004
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerill, Stephen Sean Flack, Dramane Ibrahim Laine, Ann Louise Walker
  • 5-acylamino-1,1'-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors
    Publication number: 20040242868
    Abstract: Compounds of formula (I): 1
    Type: Application
    Filed: April 15, 2004
    Publication date: December 2, 2004
    Inventors: Richard Martyn Angell, Nicola Mary Aston, Paul Bamborough, Mark James Bamford, George Stuart Cockerhill, Stephen Sean Flack, Dramane Ibrahim Laine, Suzanne Joy Merrick, Kathryn Jane Smith, Ann Louise Walker