Patents by Inventor Stephen Shaughnessy

Stephen Shaughnessy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Osteoporosis treatment with anti-IL-11 antibody
    Patent number: 6998123
    Abstract: There is disclosed a process of treating or alleviating the symptoms of pathological conditions in which bone density is decreased, which comprises inhibiting, in a mammalian patient suffering from such a condition, the formation in vivo of a tertiary complex of IL-11, its cell surface membrane receptor and the cell surface glycoprotein gp130. Examples of such substances are recombinant soluble IL-11 receptor mutants modified, as compared with native IL-11 receptor, at their gp130 binding site, and peptides which can interact with IL-11. The process of the invention not only inhibits bone resorption and hence bone loss, but also increases the process of bone formation to increase bone density.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: February 14, 2006
    Inventors: Stephen Shaughnessy, Richard Carl Austin
  • Osteoporosis treatment
    Patent number: 6846907
    Abstract: There is disclosed a process of treating or alleviating the symptoms of pathological conditions in which bone density is decreased, which comprises inhibiting, in a mammalian patient suffering from such a condition, the formation in vivo of a tertiary complex of IL-11, its cell surface membrane receptor and the cell surface glycoprotein gp130. Examples of such substances are recombinant soluble IL-11 receptor mutants modified, as compared with native IL-11 receptor, at their gp130 binding site, and peptides which can interact with IL-11. The process of the invention not only inhibits bone resorption and hence bone loss, but also increases the process of bone formation to increase bone density.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: January 25, 2005
    Assignees: Hamilton Civic Hospitals Research Centre, MDS Ocata, Inc.
    Inventors: Stephen Shaughnessy, Richard Carl Austin
  • Osteoporosis treatment
    Publication number: 20040142871
    Abstract: There is disclosed a process of treating or alleviating the symptoms of pathological conditions in which bone density is decreased, which comprises inhibiting, in a mammalian patient suffering from such a condition, the formation in vivo of a tertiary complex of IL-11, its cell surface membrane receptor and the cell surface glycoprotein gp130. Examples of such substances are recombinant soluble IL-11 receptor mutants modified, as compared with native IL-11 receptor, at their gp130 binding site, and peptides which can interact with IL-11. The process of the invention not only inhibits bone resorption and hence bone loss, but also increases the process of bone formation to increase bone density.
    Type: Application
    Filed: February 17, 2004
    Publication date: July 22, 2004
    Inventors: Stephen Shaughnessy, Richard Carl Austin