Patents by Inventor Stephen Smerdon

Stephen Smerdon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for cancer treatment relating to BRCA1 BRCT domain recognition of phosphorylated BACH1
    Publication number: 20060052951
    Abstract: The present invention relates to compounds (e.g., peptidomimetics and non-peptides) that treat, prevent, or stabilize cellular proliferative disorders and methods of treating, preventing, or stabilizing such disorders. The invention also provides three-dimensional structures of a BRCT domain-BACH1 phosphopeptide complex.
    Type: Application
    Filed: May 9, 2005
    Publication date: March 9, 2006
    Inventors: Michael Yaffe, Julie Clapperton, Isaac Manke, Drew Lowery, Stephen Smerdon
  • Products and processes for modulating peptide-peptide binding domain interactions
    Publication number: 20050196808
    Abstract: The present invention relates to therapeutic compounds and methods of use of these therapeutic compounds for treating cellular proliferative disorders. The invention also provides three-dimensional structures of a Polo-like kinase and methods for designing or selecting small molecule inhibitors using these structures, and the therapeutic use of such compounds. The invention also includes a method for identifying novel phosphopeptide-binding domains.
    Type: Application
    Filed: November 14, 2003
    Publication date: September 8, 2005
    Inventors: Michael Yaffe, Andrew Elia, Peter Rellos, Lewis Cantley, Stephen Smerdon, Isaac Manke